Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2070 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-09-26

Study Completion Date

2026-09-30

Brief Summary

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The purpose of this study is to find out the genetic and biochemical makeup of your neuroblastic tumor, which influences its aggressiveness and the suitable therapy. These research studies include surface marker analysis, cytogenetics, cancer genes,genome sequencing, tumor growth-related genes and tumor growth in test tubes. Your blood, marrow, and hematopoietic stem cell samples will also be tested for tumors or leukemia cells, and your serum tested for anti-tumor antibodies.

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Detailed Description

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To collect tumor, marrow specimens prospectively to study the molecular-genetic makeup of individual neuroblastic tumor and its metastasis by blood and marrow, and to correlate these findings with clinical outcome, and to relate the signaling circuitry of neuroblastic tumors to that of embryonic neuroectodermal cells. .

Conditions

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Neuroblastoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Tumor and Marrow Markers

Intervention Type OTHER

Tumor and Marrow Markers

Interventions

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Tumor and Marrow Markers

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Neuroblastic tumors diagnosed in accordance with the International Neuroblastoma Staging System

OR

* Clinically suspected neuroblastic tumors.

* Patients who receive naxitamab as part of their standard of care