Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up

NCT ID: NCT00563485

Last Updated: 2011-06-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-10-31

Study Completion Date

2006-11-30

Brief Summary

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The purpose of the study is to compare two alpha blockers, terazosin and doxazosin GITS, in achieving a successful TWOC after AUR due to BPH, among Chinese males in Hong Kong, and in delaying or avoiding a TURP.

Detailed Description

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Conditions

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Prostatic Hyperplasia Urinary Retention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Doxazosin GITS (Cardura XL)

Intervention Type DRUG

Terazosin (Hytrin)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Aged 50 or above
* Admitted for AUR due to BPH with PVR of 500 ml or more

Exclusion Criteria

* Previous history of TURP
* Use of alpha blockers within recent 8 months
* Renal impairment (serum creatinine \>140 umol/l)
* Poor premorbid state
Minimum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Hospital Authority, Hong Kong

OTHER_GOV

Sponsor Role lead

Principal Investigators

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Chi Wai Cheng, Dr

Role: PRINCIPAL_INVESTIGATOR

Department of Surgery, Division of Urology, North District Hospital/ The Chinese University of Hong Kong

Locations

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Prince of Wales Hospital

Hong Kong, , China

Site Status

Countries

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China

Other Identifiers

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HARECCTR0500049

Identifier Type: -

Identifier Source: secondary_id

CRE-2005.313-T

Identifier Type: -

Identifier Source: org_study_id

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