Tracheal Mechanics During Bronchoscopy

NCT ID: NCT00536315

Last Updated: 2017-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

145 participants

Study Classification

OBSERVATIONAL

Study Start Date

1999-03-01

Study Completion Date

2009-06-30

Brief Summary

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The main purpose of this study is use a new type of measurement to help decide what kind of therapy would help people with a collapsing windpipe or tracheomalacia.

Detailed Description

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This study is to obtain new information about the pressures required to collapse the trachea in patients with and without obstructive pulmonary disease and to describe the relationship between pressures and airflow obstruction. This information will provide normative data not currently available and would establish whether tracheal collapse is due to tracheomalacia. The data may lead to better ways of predicting if a patient would benefit from procedures to prevent tracheal collapse.

Conditions

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Tracheomalacia Tracheobronchomalacia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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COPD

Patients with cough and/or shortness of breath who may have windpipe collapse.

No interventions assigned to this group

Healthy adults

Subjects without symptoms for comparison.

No interventions assigned to this group

Tracheomalacia

Patients with cough and/or shortness of breath who may have windpipe collapse.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Suspicion of tracheal collapse undergoing bronchoscopy
* Healthy control subject undergoing bronchoscopy for another purpose.

Exclusion Criteria

* Esophageal pathology
* Tracheostomy
* inability to follow commands
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beth Israel Deaconess Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Stephen Loring

Professor of Anaesthesia

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stephen H Loring, M.D.

Role: PRINCIPAL_INVESTIGATOR

Beth Israel Deaconess Medical Center

Locations

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Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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Loring SH, O'donnell CR, Feller-Kopman DJ, Ernst A. Central airway mechanics and flow limitation in acquired tracheobronchomalacia. Chest. 2007 Apr;131(4):1118-24. doi: 10.1378/chest.06-2556.

Reference Type RESULT
PMID: 17426218 (View on PubMed)

Other Identifiers

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2001P001418

Identifier Type: -

Identifier Source: org_study_id

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