Assessment and Rehabilitation of Cognitive Impairments in Pediatric Survivors of Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

72 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-08-31

Study Completion Date

2012-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This research involves assessment of cognitive outcome in childhood cancer as well as evaluation of a cognitive rehabilitation program for improving learning and problem solving difficulties in children with cancer.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Understanding the Late Effects of Surviving a Pediatric Brain Tumor

NCT03208387

Brain Tumor Pediatric Brain Tumor Pediatric Cancer

ACTIVE_NOT_RECRUITING

Efficacy of Cognitive and Physical Trainings in Pediatric Cancer Survivors

NCT02749877

Pediatric Cancer

COMPLETED NA

Development of the Pediatric Neurocognitive Functioning Questionnaire

NCT03213431

Neurocognitive Disorders

COMPLETED

Neuroplasticity-Based Cognitive Remediation for Pediatric Brain Tumor Survivors

NCT02129712

Brain Tumor

COMPLETED NA

Working Memory Performance Among Childhood Brain Tumor Survivors

NCT00693914

Brain Tumors

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The purpose of this study is to help determine specific cognitive-behavioral and neurobiologic impairments associated with chemotherapy treatments in children with cancer and to assess the efficacy of a cognitive intervention program for improving cognitive impairments in these children.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Neoplasms

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Cancer patients

Children with cancer aged 8 to 16 years

No interventions assigned to this group

Control (non-cancer)

Normal children aged 8 to 16 years, age- and gender-matched to the cancer cohort

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Everyone:

* At least 9 years of age and less than 17 years

Patients

* Diagnosis of brain tumor or acute lymphocytic leukemia (ALL)
* Completed all anti-cancer treatment(s) including chemotherapy, radiation and/or surgery

Control group

* Typical for age

EXCLUSION

Everyone:

* Non-English speaking (translated cognitive testing and MRI assessments unavailable)
* MRI contraindication, including but not limited to orthodontia, metal implants, and/or pacemaker
* Major sensory deficit disorders, including but not limited to blindness or deafness

Patients

* Shunt placement
* Received bone marrow transplant
* History of neurologic, psychiatric, developmental or major medical condition (eg, diabetes) NOT related to cancer
* Participation in any concurrent cognitive rehabilitation study

Control group

* History of neurologic, psychiatric, developmental or major medical condition (eg, diabetes)

Minimum Eligible Age

9 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes