To Compare Fibrin Glue and Suture in Primary Pterygium Excision With Amniotic Membrane Transplantation
NCT ID: NCT00457223
Last Updated: 2008-02-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2/PHASE3
32 participants
INTERVENTIONAL
2007-04-30
2007-08-31
Brief Summary
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Detailed Description
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Up to our knowledge,there is no report of fibrin glue in pterygium excision with amniotic membrane transplantation(AMT). There is conventional technique to use AMT in King Chulalongkorn Memorial Hospital because some benefits over conjunctival auto-graft e.g.
* Preserve healthy superior conjunctiva for future glaucoma filtering surgery
* Can use in big or 2-headed pterygium
* Not contract as conjunctival graft esp. in case of fibrin glue
* Potential easier to use with fibrin glue
* Available from Thai Red Cross Eye Bank Comparison(s): amniotic membrane transplantation using fibrin glue compare to suture after pterygium excision.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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1Fibrin glue
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®)
Amniotic membrane transplantation using fibrin glue
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) in 16 eyes of 16 patients of FG group and continuous suture with nylon 10-0 in 16 eyes of 16 patients of SU group.
2 Suture
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using continuous suture with nylon 10-0
Amniotic membrane transplantation using fibrin glue
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) in 16 eyes of 16 patients of FG group and continuous suture with nylon 10-0 in 16 eyes of 16 patients of SU group.
Interventions
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Amniotic membrane transplantation using fibrin glue
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) in 16 eyes of 16 patients of FG group and continuous suture with nylon 10-0 in 16 eyes of 16 patients of SU group.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Recurrent pterygium
* Pseudopterygium
* Uncontrolled systemic disease.
* Known allergy to any of the study agents or preservatives used in the formulations.
18 Years
80 Years
ALL
No
Sponsors
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Chulalongkorn University
OTHER
Responsible Party
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Chulalongkorn University, Faculty of Medicine
Principal Investigators
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Ngamjit Kasetsuwan, MD
Role: STUDY_CHAIR
Ophthalmology Department, Faculty of Medicine, Chulalongkorn University
Locations
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Department of Ophthalmology, King Chulalongkorn Memorial hospital
Bangkok, , Thailand
Countries
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Other Identifiers
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401/49
Identifier Type: -
Identifier Source: org_study_id
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