The Impact of Right Ventricular Pacing on Tricuspid Regurgitation

NCT ID: NCT00419354

Last Updated: 2009-04-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-03-31

Study Completion Date

2010-03-31

Brief Summary

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"1" To examine whether right ventricular pacing has an impact on tricuspid regurgitation grade that is related to pacing rather than to valve closure interference by the electrode.

Detailed Description

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"1" Traditionally, tricuspid regurgitation in the presence of pacemaker is attributed to the physical interference of the valve closure by the electrode.

"2" Right ventricular pacing may be associated with dyssynchrony in contraction of the right ventricular wall (i.e. septum and free wall.

"3" The tricuspid sub-valvar apparatus is anchored to the septum and free wall, thus may be sensitive to dyssynchrony in those wals contraction.

"4" The study hypothesis is that the dyssynchrony in right ventricular contraction, induced by pacing, may increase tricuspid regurgitation grade and that this is a mechanism is independent of the mechanical effect of the electrode on the valve closure.

Conditions

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Tricuspid Regurgitation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age \>18 years
* Permanent pacemaker

Exclusion Criteria

* Epicardial pacing
* Left ventricular dysfunction
* Organic tricuspid regurgitation
* Bi-ventricular pacemaker
* Atrial fibrillation
* Complete pacemaker dependence
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rabin Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Rabin Medical Center

Principal Investigators

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Mordehay Vaturi, MD

Role: PRINCIPAL_INVESTIGATOR

Department of Cardiology, Rabin Medical Center

Locations

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Rabin Medical Center

Petah Tikva, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Mordehay Vaturi, MD

Role: CONTACT

97239376176

Facility Contacts

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Mordehay Vaturi, MD

Role: primary

97239376176

Other Identifiers

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4134

Identifier Type: -

Identifier Source: org_study_id

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