Effects Of Detrol LA On Memory And Cognition In Elderly Population

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-12-31

Study Completion Date

2007-06-30

Brief Summary

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The primary purpose of the trial is to show that tolterodine ER has no effect on memory and other cognitive abilities in an elderly population

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Detailed Description

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Conditions

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Memory Cognition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Tolterodine ER

Intervention Type DRUG

Oxybutynin ER

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male or female subjects with age of 65 - 75 years
* Having a score of greater than or equal to 26 on the Mini-Mental State Exam (MMSE)

Exclusion Criteria

* Current or history of bladder outlet obstruction. Previous history of acute urinary retention requiring catheterization, or severe voiding difficulties in the judgment of the investigator, prior to randomization
* Significant hepatic or renal disease, defined as twice the upper limit of the reference ranges regarding serum concentrations of AST, ALT, ALP, urea nitrogen, or creatinine

Minimum Eligible Age

65 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes