Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer

NCT ID: NCT00410618

Last Updated: 2018-07-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

42 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-04-30

Study Completion Date

2006-08-31

Brief Summary

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RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on brain function may help doctors plan cancer treatments.

PURPOSE: This clinical trial is looking at the neurological effects of chemotherapy and radiation therapy in patients with colon cancer.

Detailed Description

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OBJECTIVES:

Primary

* Identify the nature and long-term ramifications of CNS injury as a result of cancer treatment in patients with colon cancer.

Secondary

* Analyze differences in cognitive measures and MRI data in these patients.
* Correlate MRI measures with cognitive performance in these patients.

OUTLINE: Patients undergo cognitive performance assessment and MRI.

PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.

Conditions

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Cognitive/Functional Effects Colorectal Cancer Long-term Effects Secondary to Cancer Therapy in Adults

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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cognitive assessment

Intervention Type PROCEDURE

magnetic resonance imaging

Intervention Type PROCEDURE

management of therapy complications

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

DISEASE CHARACTERISTICS:

* Diagnosis of colon cancer
* Received chemotherapy and radiotherapy for colon cancer

PATIENT CHARACTERISTICS:

* Not specified

PRIOR CONCURRENT THERAPY:

* See Disease Characteristics
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

University of Arizona

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sheryl Reminger, MD

Role: STUDY_CHAIR

University of Arizona

Locations

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Arizona Cancer Center at University of Arizona Health Sciences Center

Tucson, Arizona, United States

Site Status

Countries

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United States

Other Identifiers

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P50CA095060

Identifier Type: NIH

Identifier Source: secondary_id

View Link

P30CA023074

Identifier Type: NIH

Identifier Source: secondary_id

View Link

UARIZ-BSC-02-13

Identifier Type: OTHER

Identifier Source: secondary_id

HSCB0213

Identifier Type: -

Identifier Source: org_study_id

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