Improving the Frequency of Colonoscopy in Patients With a Previous Colorectal Polyp

NCT ID: NCT00397969

Last Updated: 2013-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

800 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-02-28

Study Completion Date

2008-06-30

Brief Summary

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RATIONALE: Receiving a reminder letter from their doctor may increase the frequency of colonoscopy in patients who have had a colorectal polyp removed.

PURPOSE: This randomized clinical trial is studying how well a reminder letter from their doctor improves the frequency of colonoscopy in patients who have had a colorectal polyp removed.

Detailed Description

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OBJECTIVES:

* Determine whether rates of surveillance colonoscopy can be substantially increased by linking computerized data on endoscopic screening procedures to computerized pathology data to identify patients with prior adenomatous polyps who are due for repeat colonoscopy.
* Evaluate whether the impact of the intervention varies by patient characteristics, including age, sex, or site of primary care.

OUTLINE: This is a randomized, controlled, crossover study. Patients are stratified according to age (≤ 65 years of age vs \> 65 years of age), gender, time elapsed since last colonoscopy, and primary care physician's (PCP) membership in Harvard Vanguard Medical Associates (yes vs no). Patients are randomized to 1 of 2 arms.

* Arm I: PCPs are mailed response forms (regarding the disposition of their eligible patients \[e.g. patient letter mailed, patient called, scheduled for colonoscopy, colonoscopy completed elsewhere, patient refused procedure, clinical contraindication, patient deceased\]) and letters reminding them that their patients are due for a follow-up colonoscopy. PCPs who do not return response forms within 4 weeks are sent a second set of reminders and patient letters.
* Arm II: Six months after the beginning of the study, PCPs are mailed response forms and patient letters once. A second set of reminders and patient letters are not sent.

PROJECTED ACCRUAL: A total of 800 patients will be accrued for this study.

Conditions

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Colorectal Cancer Precancerous Condition

Keywords

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colon cancer rectal cancer precancerous condition

Study Design

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Allocation Method

RANDOMIZED

Interventions

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counseling intervention

Intervention Type OTHER

screening colonoscopy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

DISEASE CHARACTERISTICS:

* Prior diagnosis of adenomatous polyp
* Underwent prior colonoscopy with polypectomy at Brigham and Women's Hospital

* Due for repeat colonoscopy according to current national guidelines of the American Gastroenterology Association (no colonoscopy within the past 5 years)

PATIENT CHARACTERISTICS:

* Not specified

PRIOR CONCURRENT THERAPY:

* See Disease Characteristics
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Harvard Medical School (HMS and HSDM)

OTHER

Sponsor Role lead

Principal Investigators

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John Ayanian, MD, MPP

Role: STUDY_CHAIR

Harvard Medical School (HMS and HSDM)

Locations

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Dana-Farber/Brigham and Women's Cancer Center

Boston, Massachusetts, United States

Site Status

Harvard Medical School

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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Ayanian JZ, Sequist TD, Zaslavsky AM, Johannes RS. Physician reminders to promote surveillance colonoscopy for colorectal adenomas: a randomized controlled trial. J Gen Intern Med. 2008 Jun;23(6):762-7. doi: 10.1007/s11606-008-0576-2. Epub 2008 Apr 2.

Reference Type DERIVED
PMID: 18386103 (View on PubMed)

Other Identifiers

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HMS-M11837-103

Identifier Type: -

Identifier Source: secondary_id

BWH-2005-P-000371/3

Identifier Type: -

Identifier Source: secondary_id

HPHC-1705

Identifier Type: -

Identifier Source: secondary_id

CDR0000492752

Identifier Type: -

Identifier Source: org_study_id