PK Study in 3- to 6- Month-Old Children (0476-268)(COMPLETED)

NCT ID: NCT00394069

Last Updated: 2024-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-07-31

Study Completion Date

2003-12-31

Brief Summary

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The purpose of this study is to look at the preliminary safety profile of an investigational drug in children 3 to 6 months of age with bronchiolitis.

Detailed Description

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Conditions

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Bronchiolitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Study Groups

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Montelukast sodium

Participants receive montelukast sodium for 14 days.

Group Type EXPERIMENTAL

MK-0476, montelukast sodium

Intervention Type DRUG

Duration of Treatment: 14 Days

Interventions

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MK-0476, montelukast sodium

Duration of Treatment: 14 Days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Active bronchiolitis or a history of bronchiolitis and asthma-like symptoms

Exclusion Criteria

* A history of any significant illness that will pose additional risk to the patient
Minimum Eligible Age

3 Months

Maximum Eligible Age

6 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Organon and Co

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Medical Monitor

Role: STUDY_DIRECTOR

Merck Sharp & Dohme LLC

References

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Knorr B, Maganti L, Ramakrishnan R, Tozzi CA, Migoya E, Kearns G. Pharmacokinetics and safety of montelukast in children aged 3 to 6 months. J Clin Pharmacol. 2006 Jun;46(6):620-7. doi: 10.1177/0091270006288324.

Reference Type BACKGROUND
PMID: 16707408 (View on PubMed)

Other Identifiers

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2006_545

Identifier Type: -

Identifier Source: secondary_id

0476-268

Identifier Type: -

Identifier Source: org_study_id

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