PPI Sequencing Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-09-30

Study Completion Date

2007-05-31

Brief Summary

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The purpose of this study is to assess how patients with gastro-oesophageal reflux disease (heartburn) who are currently receiving treatment with a proton pump inhibitor but are still experiencing symptoms will benefit from a change in treatment.

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Detailed Description

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Conditions

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Gastro-Oesophageal Reflux Disease

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Esomeprazole

Intervention Type DRUG

Physical exam

Intervention Type PROCEDURE

Pregnancy test if applicable

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Persisting symptoms of GORD despite previous treatment with a full dose proton pump inhibitor
* Informed consent
* Over 18 years of age

Exclusion Criteria

* Current course of Proton Pump inhibitor treatment for more than 8 weeks prior to enrolment in the study;
* More than 1 other course of PPI treatment in the previous 12 month;
* Previous use of esomeprazole;
* Presence of alarm symptoms.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No