Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD)

NCT ID: NCT00365300

Last Updated: 2010-05-04

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

129 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-09-30

Study Completion Date

2007-11-30

Brief Summary

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To assess the efficacy of pantoprazole for the treatment of infants with symptomatic Gastroesophageal Reflux Disease (GERD).

Detailed Description

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Conditions

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Gastroesophageal Reflux

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Pantoprazole

Group Type ACTIVE_COMPARATOR

pantoprazole

Intervention Type DRUG

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Interventions

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pantoprazole

Intervention Type DRUG

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* term or post term infants beyond the neonatal period of an age greater than 28 days but less than or equal to 11 months
* clinical diagnosis of GERD
* weight greater than 2.5 kg and less than or equal to 15 kg

Exclusion Criteria

* known history of upper GI anatomic disorders
* history of acute life-threatening medical conditions
* clinically significant medical conditions or laboratory abnormalities
Minimum Eligible Age

28 Days

Maximum Eligible Age

11 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wyeth is now a wholly owned subsidiary of Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Wyeth

Principal Investigators

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Medical Monitor

Role: STUDY_DIRECTOR

Wyeth is now a wholly owned subsidiary of Pfizer

Locations

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Mobile, Alabama, United States

Site Status

Phoenix, Arizona, United States

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Little Rock, Arkansas, United States

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Oakland, California, United States

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Orange, California, United States

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Washington D.C., District of Columbia, United States

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Miami, Florida, United States

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Orlando, Florida, United States

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Pensacola, Florida, United States

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Tampa, Florida, United States

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Augusta, Georgia, United States

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Peoria, Illinois, United States

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Bardstown, Kentucky, United States

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Louisville, Kentucky, United States

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Boston, Massachusetts, United States

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Flint, Michigan, United States

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Jackson, Mississippi, United States

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Omaha, Nebraska, United States

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Las Vegas, Nevada, United States

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Camden, New Jersey, United States

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Mays Landing, New Jersey, United States

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Morristown, New Jersey, United States

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Brooklyn, New York, United States

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Buffalo, New York, United States

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Valhalla, New York, United States

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Durham, North Carolina, United States

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Cincinnati, Ohio, United States

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Oklahoma City, Oklahoma, United States

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Bethlehem, Pennsylvania, United States

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Memphis, Tennessee, United States

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Temple, Texas, United States

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Salt Lake City, Utah, United States

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Burlington, Vermont, United States

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Norfolk, Virginia, United States

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Richmond, Virginia, United States

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Huntington, West Virginia, United States

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Morgantown, West Virginia, United States

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Madison, Wisconsin, United States

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Countries

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United States

Other Identifiers

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3001B3-329

Identifier Type: -

Identifier Source: org_study_id

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