The Usefulness of HyperQ Recordings for the Early Diagnosis of Acute Coronary Syndrome in Patients Presenting With Chest Pain

NCT ID: NCT00339105

Last Updated: 2007-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-06-30

Study Completion Date

2007-01-31

Brief Summary

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The purpose of the study is to assess the usefulness of high Frequency mid-QRS analysis in identifying the ischemic origin of patients presenting to the Emergency Room (ER)with Chest pain.

Detailed Description

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Introduction:

Chest pain is the leading cause of urgent admission to the Emergency Department (ED) in western countries.Acute Coronary Syndrome(ACS) continues to be among the most difficult to predict or diagnose. Misdiagnoses may lead to discharge of patients with ACS, who should have been admitted as well as costly unnecessary hospitalizations of patients who do not have ACS.

Objectives:

To evaluate the usefulness of High Frequency mid-QRS analysis in identifying the ischemic patients out of all patients presenting to the Emergency Room (ER) with chest pain.

Comparisons:

A continuous High Frequency Mid-QRS recording will be performed using the HyperQ System (BSP Ltd.) and compared to clinical, electrophysiologic and laboratory results. The golden standards used to compare the methods will be either CT-Angio, Echocardiography or Cardiac SPECT. A follow-up inquiry will be performed after 3 months and Coronary Angiography results will be sought and compared as well.

Conditions

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Acute Coronary Syndrome

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age ≥18 years
* Patients with chest pain, with possible ACS.
* Patients admitted to the 'chest pain unit'
* Chest pain appeared within 24 hours prior to admission to the 'chest pain unit'
* No history of trauma or any other evident medical cause of chest pain
* Signed an Informed Consent

Exclusion Criteria

* Implanted pacemaker or defibrillator
* History of trauma or other evident medical cause of chest pain
* Patients admitted to Intensive Cardiac Care Unit or intermediate Cardiac Care Unit
* Patients discharged from the ER
* Patients with Bundle-Branch-Block or other intra-ventricular delay of more than 120 mSec
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sheba Medical Center

OTHER_GOV

Sponsor Role lead

Principal Investigators

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Shlomi Matetzky, MD

Role: PRINCIPAL_INVESTIGATOR

Head of Chest Pain Unit, ER, Sheba Medical Center

Locations

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The Chest Pain Unit, ER, Sheba Medical Center, Tel-Hashomer

Ramat Gan, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Shlomi Matetzky, MD

Role: CONTACT

+972-52-6667122

References

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Abboud S, Zlochiver S. High-frequency QRS electrocardiogram for diagnosing and monitoring ischemic heart disease. J Electrocardiol. 2006 Jan;39(1):82-6. doi: 10.1016/j.jelectrocard.2005.09.007. No abstract available.

Reference Type BACKGROUND
PMID: 16387057 (View on PubMed)

Related Links

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http://www.bsp.co.il

BSP Ltd. is the company that developed the HyperQ system

Other Identifiers

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SHEBA-06-4114-SM-CTIL

Identifier Type: -

Identifier Source: org_study_id

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