Exercise Program or Health Education Program in Reducing Fatigue and Pain in Breast Cancer Survivors

NCT ID: NCT00336089

Last Updated: 2013-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Brief Summary

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RATIONALE: An exercise program or health education program may help relieve fatigue and pain and improve the quality of life in women who are breast cancer survivors. It is not yet known whether an exercise program is more effective than a health education program or no program in reducing fatigue and pain in women who are breast cancer survivors.

PURPOSE: This randomized clinical trial is studying an exercise program to see how well it works in reducing fatigue and pain compared to a health education program or no program in women who are breast cancer survivors.

Detailed Description

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OBJECTIVES:

* Determine whether a moderate-intensity exercise program comprising cardiorespiratory and resistance training of the legs, back, abdominal, trunk, and arm musculature vs a control group attenuates fatigue and pain in breast cancer survivors.
* Determine whether this exercise program will significantly improve the quality of life of these patients.
* Determine whether this exercise program can significantly reduce the number of days of absenteeism from work in these patients.
* Determine whether this exercise program can significantly attenuate mood disturbances in these patients.

OUTLINE: This is a randomized, controlled, pilot study. Patients are randomized to 1 of 2 treatment arms.

* Arm I (exercise program): Patients participate in an exercise program comprising cardiorespiratory (walking on a treadmill) and resistance training for 1 hour, 3 times weekly for 12 weeks.
* Arm II (control): Patients undergo no intervention. In both arms, patients complete questionnaires regarding general health, mood, work attendance, and physical activity before the start of study treatment and then every 3 weeks for 12 weeks. Patients also complete a 7-day physical activity diary and sleep diary every 3 weeks.

PROJECTED ACCRUAL: A total of 54 patients will be accrued for this study.

Conditions

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Breast Cancer Cancer Survivor Fatigue Pain

Keywords

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fatigue pain cancer survivor breast cancer in situ inflammatory breast cancer stage IA breast cancer stage IB breast cancer stage II breast cancer stage IIIA breast cancer stage IIIB breast cancer stage IIIC breast cancer stage IV breast cancer recurrent breast cancer

Study Design

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Allocation Method

RANDOMIZED

Interventions

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exercise intervention

Intervention Type BEHAVIORAL

educational intervention

Intervention Type OTHER

complementary or alternative medicine procedure

Intervention Type PROCEDURE

fatigue assessment and management

Intervention Type PROCEDURE

management of therapy complications

Intervention Type PROCEDURE

pain therapy

Intervention Type PROCEDURE

quality-of-life assessment

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

DISEASE CHARACTERISTICS:

* Breast cancer survivor
* Received adjuvant chemotherapy or radiotherapy for breast cancer only

* Must have completed treatment 2-6 months ago
* Hormone receptor status not specified

PATIENT CHARACTERISTICS:

* Female
* Menopausal status not specified
* Hemoglobin ≥ 11 g/dL
* Able to read English
* No high-risk for cardiovascular problems during exercise, including any of the following:

* Unstable heart disease
* Unstable angina
* Chronic respiratory disease
* Dizziness
* Uncontrolled hypertension
* No severe respiratory disease requiring oxygen therapy
* No history of anorexia (body mass index \[BMI\] \< 18.5) or severe obesity (BMI \> 35)
* No history of multiple cancers
* No shortness of breath or hypotension
* No sudden swelling of the ankles, hands or face
* No palpitations or arrhythmias
* No persistent and intolerable pain
* No major acute illness (e.g., fever or respiratory infection)

PRIOR CONCURRENT THERAPY:

* See Disease Characteristics
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Clayton State University

OTHER

Sponsor Role lead

Principal Investigators

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Melanie Poudevigne, PhD

Role: STUDY_CHAIR

Clayton State University

Locations

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Saint Joseph's Hospital of Atlanta

Atlanta, Georgia, United States

Site Status RECRUITING

Clayton State University

Morrow, Georgia, United States

Site Status RECRUITING

Countries

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United States

Facility Contacts

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Clinical Trials Office - Saint Joseph's Hospital of Atlanta

Role: primary

Melanie Poudevigne, PhD

Role: primary

Other Identifiers

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CSU-GCC-161

Identifier Type: -

Identifier Source: secondary_id

CDR0000466676

Identifier Type: -

Identifier Source: org_study_id