Mechanism of Thrombocytopenia in Infants

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-06-30

Study Completion Date

2008-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This research project is studying the causes for low platelet levels in preterm infants. Platelets are a component of blood that helps with clotting. The purpose of this study is to determine whether the cause for low platelet levels is the same in infants who are born to mothers with preeclampsia and infants who are small for gestational age.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Platelet Count Trends in Pre-eclamptic Parturients

NCT00787241

Obstetric Labor Complications Preeclampsia Thrombocytopenia

COMPLETED

Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn

NCT01648855

Preterm Birth Intra-uterine Growth Restriction Maternal Preeclampsia +1 more

COMPLETED

Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development

NCT02639676

Preeclampsia

COMPLETED

Endothelial Progenitor Cells in Umbilical Cord Blood in Preeclampsia and IUGR

NCT00634855

Preeclampsia IUGR

TERMINATED

Left Ventricular and Endothelial Function in Preeclampsia

NCT00201500

Preeclampsia

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Thrombocytopenia is a common entity in infants who are born to mothers with preeclampsia and in infants who are small for gestational age. There have been several theories to the mechanism underlying thrombocytopenia in these groups of patients. One mechanism suggests that thrombocytopenia in these populations may be secondary to underproduction of platelets. Other studies have implied that low platelet levels may be due to endothelial activation causing platelet consumption. This study is being performed to help determine the mechanism causing thrombocytopenia in infants born to mothers with preeclampsia and comparing it to the mechanism of thrombocytopenia in infants who are small for gestational age.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Thrombocytopenia Small for Gestational Age (SGA) Preeclampsia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

SGA infants

Infants who are thought to be small for gestational age (SGA)

Cord blood

Intervention Type PROCEDURE

Cord blood will be obtained at the time of delivery.

Pre-eclampsia exposed

Infants who are born to mothers who had pre-eclampsia

Cord blood

Intervention Type PROCEDURE

Cord blood will be obtained at the time of delivery.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cord blood

Cord blood will be obtained at the time of delivery.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Infants who are less than 34 weeks gestation
* Infants born to mothers with preeclampsia
* Infants who are born small for gestational age whose mother did not have preeclampsia