Amisulpride in Schizophrenic Patients

NCT ID: NCT00331981

Last Updated: 2008-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

138 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-02-29

Brief Summary

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Primary purpose:

* To find out how effective is long term treatment with amisulpride on the positive and negative symptoms in schizophrenic patients
* To find out how safe is long term treatment with amisulpride in schizophrenic patients

Secondary purpose:

* To find out how effective is long term treatment with amisulpride on the quality of life in schizophrenic patients
* To find out how effective is long term treatment with amisulpride on the cognitive function in schizophrenic patients

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Amisulpride

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed as schizophrenia or schizophrenic disorder according to DSM-IV
* Patients who need new anti-psychotic drugs or need to change the medication due to aggravations of symptoms or recurrence

Exclusion Criteria

* Patients with positive symptoms in whom the disorder does not correspond to schizophrenic criteria. (e.g, schizoaffective disorder)
* Patients hypersensitive to the active ingredient or to other ingredients of the study drug
* Prolactin-dependant tumors, pituitary gland prolactinomas and breast cancer
* Pheochromocytoma or Parkinson's disease
* Pregnancy or breast feeding
* Current or recently withdrawn from drug abuse or alcoholism
* Chronic renal failure and other internal or surgical disease which physician decides will be worsened by trial medication or that will affect the metabolism or effects of the trial medication
* Patients with previous histories and clinical improvement was not seen in spite of treatment with 2 anti-psychotics for over 8 weeks
* Slow heart rate of \<55bpm, low blood potassium level, congenital prolongation of the QT interval
* Current treatment with a drug likely to cause markedly slow heart rate(\<55bpm), low blood potassium level, slowing of intercardiac condition or prolongation of the QT interval

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sanofi

INDUSTRY

Sponsor Role lead

Principal Investigators

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Won Sik Lee, MD, PhD

Role: STUDY_DIRECTOR

Sanofi

Locations

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Sanofi-Aventis

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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L_8968

Identifier Type: -

Identifier Source: org_study_id