Safety and Efficacy Study of an Interactive Wound Dressing (KC002) for the Treatment of Diabetic Foot Ulcers

NCT ID: NCT00330265

Last Updated: 2008-08-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Study Completion Date

2009-09-30

Brief Summary

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The objective of this study is to determine the safety and effectiveness of a device (the KC-002 interactive wound dressing) in the promotion of healing in diabetic foot ulcers as compared with a conventional wound therapy regimen for subjects with Type 1 or Type 2 diabetes mellitus.

This is a prospective, randomized, multi-center, unmasked, controlled study. All patients will receive care for the diabetic foot ulcer during the study.

Participation in the study is for 24 weeks.

Detailed Description

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Conditions

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Foot Ulcer Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

KC-002

Group Type EXPERIMENTAL

KC-002

Intervention Type DEVICE

Determine the safety and effectiveness of a device (the KC-002 interactive wound dressing) in the promotion of healing in diabetic foot ulcers as compared with a conventional wound therapy regimen for subjects with Type 1 or Type 2 diabetes mellitus.

2

Conventional Wound Therapy

Group Type OTHER

Conventional Wound Therapy

Intervention Type OTHER

Normal Saline Dressings

Interventions

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KC-002

Determine the safety and effectiveness of a device (the KC-002 interactive wound dressing) in the promotion of healing in diabetic foot ulcers as compared with a conventional wound therapy regimen for subjects with Type 1 or Type 2 diabetes mellitus.

Intervention Type DEVICE

Conventional Wound Therapy

Normal Saline Dressings

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Participants included in the study must:

* Have Type 1 or Type 2 diabetes mellitus
* Have a diabetic foot ulcer on the bottom of the foot or heal which has been present for three (3) weeks but less than two (2) years and is sufficient size to qualify for the study
* Be able to visit the study doctor regularly for 24 weeks

Exclusion Criteria

Participants may not be included if:

* The diabetic foot ulcer is infected
* They have poor circulation in their study foot
* Cannot or will not wear a special boot to take pressure off the study ulcer
* They have certain other diseases or laboratory values which are not within a specified range
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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KeraCure

INDUSTRY

Sponsor Role lead

Responsible Party

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KeraCure

Locations

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Institute for Advanced Wound Care at Baptist Medical Center South

Montgomery, Alabama, United States

Site Status RECRUITING

HOPE Research Institute

Phoenix, Arizona, United States

Site Status RECRUITING

Southern Arizona VA Health Care System

Tucson, Arizona, United States

Site Status RECRUITING

Roy Kroeker, DPM

Fresno, California, United States

Site Status RECRUITING

Felix Sigal, DPM

Los Angeles, California, United States

Site Status RECRUITING

Bay Area Foot Care

San Francisco, California, United States

Site Status RECRUITING

North American Center for Limb Preservation

New Haven, Connecticut, United States

Site Status RECRUITING

Georgetown University / Wound Healing Center

Washington D.C., District of Columbia, United States

Site Status RECRUITING

Doctor's Research Network

South Miami, Florida, United States

Site Status RECRUITING

Medical Associates

Clinton, Iowa, United States

Site Status RECRUITING

Sinai Hospital of Baltimore

Baltimore, Maryland, United States

Site Status RECRUITING

Preston Family Building

Boston, Massachusetts, United States

Site Status RECRUITING

Foot Healthcare Associates, PC

Livonia, Michigan, United States

Site Status RECRUITING

St. Vincent Health Center Wound Clinic

Erie, Pennsylvania, United States

Site Status RECRUITING

Pivotal Clinical Research

Souderton, Pennsylvania, United States

Site Status RECRUITING

Warren General Hospital Wound Clinic

Warren, Pennsylvania, United States

Site Status RECRUITING

Martin Foot and Ankle

York, Pennsylvania, United States

Site Status RECRUITING

San Antonio Podiatry Associates, PC

San Antonio, Texas, United States

Site Status RECRUITING

Pharmaceutical Research Organization

Bountiful, Utah, United States

Site Status RECRUITING

Dixie Regional Medical Center's Wound Clinic

St. George, Utah, United States

Site Status RECRUITING

Central Washington Podiatry Service

Yakima, Washington, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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M Meek

Role: CONTACT

Phone: 866-537-2287

Email: [email protected]

Facility Contacts

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Other Identifiers

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NCT 20051320

Identifier Type: -

Identifier Source: org_study_id