Kinetics of B Cell Response in Infants Menjugate Vaccination

NCT ID: NCT00310700

Last Updated: 2014-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-05-31

Study Completion Date

2005-11-30

Brief Summary

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Kinetics of B cell response in infants Menjugate vaccination

Detailed Description

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Conditions

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Prevention of Meningococcal Infection

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Interventions

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Meningococcal C conjugate vaccine

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* healthy infants

Exclusion Criteria

* previously ascertained or suspected disease caused by N. meningitidis
* previous household contact with an individual with a positive culture of N. meningitidis serogroup C
Minimum Eligible Age

8 Weeks

Maximum Eligible Age

11 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Novartis Vaccines

INDUSTRY

Sponsor Role collaborator

Novartis

INDUSTRY

Sponsor Role lead

Principal Investigators

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Novartis Vaccines - Information Services

Role: PRINCIPAL_INVESTIGATOR

Novartis Vaccines & Diagnostics

Locations

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Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital

Oxford, Oxon, United Kingdom

Site Status

Countries

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United Kingdom

References

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Kelly DF, Snape MD, Perrett KP, Clutterbuck EA, Lewis S, Blanchard Rohner G, Jones M, Yu LM, Pollard AJ. Plasma and memory B-cell kinetics in infants following a primary schedule of CRM 197-conjugated serogroup C meningococcal polysaccharide vaccine. Immunology. 2009 May;127(1):134-43. doi: 10.1111/j.1365-2567.2008.02934.x.

Reference Type BACKGROUND
PMID: 19175802 (View on PubMed)

Other Identifiers

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Impact N° 1457

Identifier Type: -

Identifier Source: secondary_id

2004-004962-33

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

M14P5

Identifier Type: -

Identifier Source: org_study_id

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