Safety and Efficacy of Ciclesonide in Pediatric Patients (6 to 11 Years of Age) With Seasonal Allergic Rhinitis (BY9010/M1-417)

NCT ID: NCT00305487

Last Updated: 2016-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

660 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-31

Study Completion Date

2006-10-31

Brief Summary

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The aim of the study is to determine the efficacy and safety of ciclesonide nasal spray in children with seasonal allergic rhinitis. Ciclesonide will be administered intranasally at two dose levels once daily. The study consists of a baseline period (1 to 3 weeks) and a treatment period (2 weeks).

Detailed Description

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Conditions

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Hay Fever Seasonal Allergic Rhinitis

Keywords

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Hay Fever Seasonal Allergic Rhinitis Nasal spray Ciclesonide Allergic Rhinitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Ciclesonide nasal spray

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Written informed consent
* General good health other than seasonal allergic rhinitis
* Positive standard skin prick test

Exclusion Criteria

* Pregnancy, nursing, or plans to become pregnant or donate gametes for in vitro fertilization
* Participation in any investigational drug trial within the 30 days preceding the Screening Visit
* A known hypersensitivity to any corticosteroid or any of the ingredients in the study drug formulation
* Plans to travel outside the study area (the known pollen area for the investigative site) for 24 hours or more during the final 7 days of the baseline period
* Plans to travel outside the study area (the known pollen area for the investigative site) for more than 2 consecutive days OR more than 3 days total during the treatment period
* Use of any prohibited concomitant medications
* Non-vaccinated exposure to or active infection with chickenpox or measles within the 21 days preceding the Screening Visit
* Use of antiepileptic drugs for epilepsy within 30 days of the Screening Visit
* Study participation by more than one patient from the same household
Minimum Eligible Age

6 Years

Maximum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AstraZeneca

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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AstraZeneca AstraZeneca

Role: STUDY_DIRECTOR

AstraZeneca

Locations

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Altana Pharma/Nycomed

Birmingham, Alabama, United States

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Altana Pharma/Nycomed

Hot Springs, Arkansas, United States

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Altana Pharma/Nycomed

Costa Mesa, California, United States

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Altana Pharma/Nycomed

Huntington Beach, California, United States

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Altana Pharma/Nycomed

Long Beach, California, United States

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Altana Pharma/Nycomed

Los Alamitos, California, United States

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Altana Pharma/Nycomed

Mission Viejo, California, United States

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Altana Pharma/Nycomed

Orange, California, United States

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Altana Pharma/Nycomed

Roseville, California, United States

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Altana Pharma/Nycomed

San Diego, California, United States

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Altana Pharma/Nycomed

San Diego, California, United States

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Altana Pharma/Nycomed

San Jose, California, United States

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Altana Pharma/Nycomed

Stockton, California, United States

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Altana Pharma/Nycomed

Colorado Springs, Colorado, United States

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Altana Pharma/Nycomed

Denver, Colorado, United States

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Altana Pharma/Nycomed

Englewood, Colorado, United States

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Altana Pharma/Nycomed

Lakewood, CO, Colorado, United States

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Altana Pharma/Nycomed

Atlanta, Georgia, United States

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Altana Pharma/Nycomed

Gainesville, Georgia, United States

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Altana Pharma/Nycomed

Savannah, Georgia, United States

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Altana Pharma/Nycomed

Woodstock, GA, Georgia, United States

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Altana Pharma/Nycomed

Normal, Illinois, United States

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Altana Pharma/Nycomed

Indianapolis, Indiana, United States

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Altana Pharma/Nycomed

Overland Park, Kansas, United States

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Altana Pharma/Nycomed

Louisville, KY, Kentucky, United States

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Altana Pharma/Nycomed

Metairie, Louisiana, United States

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Altana Pharma/Nycomed

Shreveport, Louisiana, United States

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Altana Pharma/Nycomed

Bethesda, Maryland, United States

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Altana Pharma/Nycomed

North Dartmouth, Massachusetts, United States

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Altana Pharma/Nycomed

Minneapolis, Minnesota, United States

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Altana Pharma/Nycomed

Jefferson City, Missouri, United States

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Altana Pharma/Nycomed

Rolla, Missouri, United States

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Altana Pharma/Nycomed

St Louis, Missouri, United States

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Altana Pharma/Nycomed

Lincoln, NE, Nebraska, United States

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Altana Pharma/Nycomed

Papillion, Nebraska, United States

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Altana Pharma/Nycomed

Brick, New Jersey, United States

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Altana Pharma/Nycomed

Forked River, New Jersey, United States

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Altana Pharma/Nycomed

Red Bank, New Jersey, United States

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Altana Pharma/Nycomed

Skillman, New Jersey, United States

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Altana Pharma/Nycomed

Warren Township, New Jersey, United States

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Altana Pharma/Nycomed

Rochester, NY, New York, United States

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Altana Pharma/Nycomed

Rockville Centre, New York, United States

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Altana Pharma/Nycomed

Raleigh, North Carolina, United States

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Altana Pharma/Nycomed

Cincinnati, Ohio, United States

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Altana Pharma/Nycomed

Cincinnati, OH, Ohio, United States

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Altana Pharma/Nycomed

Ashland, Oregon, United States

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Altana Pharma/Nycomed

Lake Oswego, Oregon, United States

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Altana Pharma/Nycomed

Medford, OR, Oregon, United States

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Altana Pharma/Nycomed

Portland, Oregon, United States

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Altana Pharma/Nycomed

Blue Bell, Pennsylvania, United States

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Altana Pharma/Nycomed

Eerie, Pennsylvania, United States

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Altana Pharma/Nycomed

Pittsburgh, Pennsylvania, United States

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Altana Pharma/Nycomed

Pittsburgh, Pennsylvania, United States

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Altana Pharma/Nycomed

Upland, Pennsylvania, United States

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Altana Pharma/Nycomed

Charleston, South Carolina, United States

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Altana Pharma/Nycomed

Charleston, SC, South Carolina, United States

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Altana Pharma/Nycomed

Germantown, Tennessee, United States

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Altana Pharma/Nycomed

Jackson, Tennessee, United States

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Altana Pharma/Nycomed

Austin, Texas, United States

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Altana Pharma/Nycomed

Austin, Texas, United States

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Altana Pharma/Nycomed

Dallas, Texas, United States

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Altana Pharma/Nycomed

El Paso, Texas, United States

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Altana Pharma/Nycomed

Kerrville, Texas, United States

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Altana Pharma/Nycomed

New Braunfels, Texas, United States

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Altana Pharma/Nycomed

San Antonio, Texas, United States

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Altana Pharma/Nycomed

Salt Lake City, Utah, United States

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Altana Pharma/Nycomed

South Burlington, Vermont, United States

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Altana Pharma/Nycomed

Burke, Virginia, United States

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Altana Pharma/Nycomed

Charlottesville, Virginia, United States

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Altana Pharma/Nycomed

Richmond, Virginia, United States

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Altana Pharma/Nycomed

Milwaukee, Wisconsin, United States

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Countries

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United States

Related Links

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Other Identifiers

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BY9010/M1-417

Identifier Type: -

Identifier Source: org_study_id