Effectiveness of a Normalization of Eating Intervention Program for Treating Women With Eating Disorders

NCT ID: NCT00272545

Last Updated: 2013-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

280 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Study Completion Date

2009-02-28

Brief Summary

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This study will evaluate the effectiveness of a new approach to a normalization of eating program, based on principles of cognitive-behavioral therapy, in treating women with anorexia nervosa or bulimia nervosa.

Detailed Description

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Eating disorders are real, treatable medical illnesses. They are often characterized by disturbances in eating behavior, such as drastic reduction of food intake or extreme overeating, as well as feelings of distress or extreme concern about body shape or weight. The two main types of eating disorders are anorexia nervosa and bulimia nervosa. A third type, binge-eating disorder, is pending approval as a formal psychiatric diagnosis. Eating disorders frequently develop during adolescence or early adulthood, and they occur more often in females than in males. Studies have shown cognitive behavioral therapy (CBT) to be the most effective approach to treating eating disorders. However, the applicability of these findings to clinical settings and intensive outpatient therapy programs (IOPs) remains unknown. This study will evaluate the effectiveness of a new approach to a normalization of eating (NOE) program, based on principles of CBT, in treating women with anorexia nervosa or bulimia nervosa.

Participants in this open-label study will be assigned to receive either treatment-as-usual (TAU) or NOE. Participants admitted to the study in the first 8 months of the trial will receive TAU. Those admitted after the first 8 months will take part in the NOE program. Participants may begin receiving treatment as soon as they enter the study and will continue receiving their assigned treatments for 6 weeks. All participants in the NOE group will be required to report to the study site three evenings a week. They will receive individual therapy, as well as take part in group and family therapy sessions. In addition, they will be supervised while eating a meal. Body weight, results of the Eating Disorders Examination and the Structured Clinical Interview for DSM-IV Axis I disorders, and self-report measures will be assessed post-treatment and at the Month 6 follow-up visit.

Note: Participants are recruited from the Renfrew Center's outpatient programs located in the Philadelphia area. Individuals outside of Renfrew cannot volunteer for this study. For more information about the Renfrew Center's inpatient or outpatient treatment programs, please call 1-800-RENFREW.

Conditions

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Eating Disorders

Keywords

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Anorexia Nervosa Bulimia Nervosa Cognitive Behavioral Therapy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Participants will receive the normalization of eating program

Group Type EXPERIMENTAL

Normalization of Eating (NOE)

Intervention Type BEHAVIORAL

The NOE is a 6-week program based on principles of CBT. Participants will receive individual therapy, as well as take part in group and family therapy sessions. In addition, participants will be supervised while eating meals.

2

Participants will receive treatment as usual

Group Type ACTIVE_COMPARATOR

Treatment As Usual (TAU)

Intervention Type BEHAVIORAL

Treatment as usual will include standard care for a person with an eating disorder.

Interventions

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Normalization of Eating (NOE)

The NOE is a 6-week program based on principles of CBT. Participants will receive individual therapy, as well as take part in group and family therapy sessions. In addition, participants will be supervised while eating meals.

Intervention Type BEHAVIORAL

Treatment As Usual (TAU)

Treatment as usual will include standard care for a person with an eating disorder.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of an eating disorder or eating disorder not otherwise specified (except for binge eating disorder), as defined by the Diagnostic and Statistical Manual of the American Psychiatric Association
* Agrees to remain in IOP treatment for at least 3 weeks
* Seeking treatment in one of the Renfrew Center's outpatient programs located in the Philadelphia area

Exclusion Criteria

* Diagnosis of eating disorder not otherwise specified, including binge eating disorder
* Diagnosis of a psychotic disorder
* Transferred to inpatient treatment during the IOP stay because of worsening health
Minimum Eligible Age

15 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

Drexel University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael R. Lowe, PhD

Role: PRINCIPAL_INVESTIGATOR

Drexel University

Locations

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The Renfrew Center of Radnor

Radnor, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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R34MH071691

Identifier Type: NIH

Identifier Source: secondary_id

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DATR A2-AIR

Identifier Type: -

Identifier Source: secondary_id

R34MH071691

Identifier Type: NIH

Identifier Source: org_study_id

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