Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

NCT ID: NCT00267501

Last Updated: 2025-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-05-31

Study Completion Date

2050-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease Food Allergy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older.
* Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy OR family member, or normal control
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Children's Hospital Medical Center, Cincinnati

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Marc E. Rothenberg, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Cincinnati Children's Hospital Medical Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Bliss Magella

Role: CONTACT

513-636-7832

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Bliss Magella

Role: primary

513-636-7832

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

R01 DK075401

Identifier Type: -

Identifier Source: secondary_id

04-12-8 : 2008-0090

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

EoE Food Test Pilot Study
NCT07023380 NOT_YET_RECRUITING NA
Dupilumab Therapy for EGIDs
NCT07257835 RECRUITING
Eosinophilia Diagnosis
NCT02581514 UNKNOWN NA
Dupilumab in Eosinophilic Gastritis
NCT03678545 COMPLETED PHASE2