Safety and Efficacy of SH T00660AA in Treatment of Endometriosis

NCT ID: NCT00225186

Last Updated: 2014-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

168 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-07-31

Study Completion Date

2008-03-31

Brief Summary

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The purpose of this study is to demonstrate safety and efficacy of SH T00660AA for the treatment of endometriosis

Detailed Description

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The study has previously been posted by Schering AG, Germany. Schering AG, Germany has been renamed to Bayer Schering Pharma AG, Germany.Bayer Schering Pharma AG, Germany is the sponsor of the trial.

Conditions

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Endometriosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Visanne (SH T00660AA , BAY86-5258)

Intervention Type DRUG

Daily long-term drug treatment (12 months), and post-treatment observation (6 months) in a subgroup of patients

Interventions

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Visanne (SH T00660AA , BAY86-5258)

Daily long-term drug treatment (12 months), and post-treatment observation (6 months) in a subgroup of patients

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Female patients with endometriosis-associated pelvic pain

Exclusion Criteria

* Pregnant or lactating women
* History or suspicion of hormone dependent tumor
* Therapy resistant endometriosis or need for primary surgical treatment
* Any other conditions which forbid the participation
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Heidelberg, Baden-Wurttemberg, Germany

Site Status

Tübingen, Baden-Wurttemberg, Germany

Site Status

Krumbach, Bavaria, Germany

Site Status

München, Bavaria, Germany

Site Status

Nuremberg, Bavaria, Germany

Site Status

Giessen, Hesse, Germany

Site Status

Mühlheim am Main, Hesse, Germany

Site Status

Aachen, North Rhine-Westphalia, Germany

Site Status

Gevelsberg, North Rhine-Westphalia, Germany

Site Status

Münster, North Rhine-Westphalia, Germany

Site Status

Dippoldiswalde, Saxony, Germany

Site Status

Leipzig, Saxony, Germany

Site Status

Marienberg, Saxony, Germany

Site Status

Weißig, Saxony, Germany

Site Status

Kalbe, Saxony-Anhalt, Germany

Site Status

Lübeck, Schleswig-Holstein, Germany

Site Status

Greifswald, , Germany

Site Status

Brescia, , Italy

Site Status

Cagliari, , Italy

Site Status

Napoli, , Italy

Site Status

Roma, , Italy

Site Status

Torino, , Italy

Site Status

Chernivtsi, , Ukraine

Site Status

Kiev, , Ukraine

Site Status

Kiev, , Ukraine

Site Status

Kiev, , Ukraine

Site Status

Kiev, , Ukraine

Site Status

Vinnitsa, , Ukraine

Site Status

Countries

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Germany Italy Ukraine

References

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Strowitzki T, Faustmann T, Gerlinger C, Seitz C. Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 2010 Aug;151(2):193-8. doi: 10.1016/j.ejogrb.2010.04.002. Epub 2010 May 5.

Reference Type RESULT
PMID: 20444534 (View on PubMed)

Kohler G, Faustmann TA, Gerlinger C, Seitz C, Mueck AO. A dose-ranging study to determine the efficacy and safety of 1, 2, and 4mg of dienogest daily for endometriosis. Int J Gynaecol Obstet. 2010 Jan;108(1):21-5. doi: 10.1016/j.ijgo.2009.08.020.

Reference Type RESULT
PMID: 19819448 (View on PubMed)

Gerlinger C, Schumacher U, Faustmann T, Colligs A, Schmitz H, Seitz C. Defining a minimal clinically important difference for endometriosis-associated pelvic pain measured on a visual analog scale: analyses of two placebo-controlled, randomized trials. Health Qual Life Outcomes. 2010 Nov 24;8:138. doi: 10.1186/1477-7525-8-138.

Reference Type RESULT
PMID: 21106059 (View on PubMed)

Petraglia F, Hornung D, Seitz C, Faustmann T, Gerlinger C, Luisi S, Lazzeri L, Strowitzki T. Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment. Arch Gynecol Obstet. 2012 Jan;285(1):167-73. doi: 10.1007/s00404-011-1941-7. Epub 2011 Jun 17.

Reference Type RESULT
PMID: 21681516 (View on PubMed)

Other Identifiers

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307059

Identifier Type: OTHER

Identifier Source: secondary_id

91234

Identifier Type: -

Identifier Source: org_study_id

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