Disease Modifying Genes in Severe Asthma

NCT ID: NCT00212537

Last Updated: 2022-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

941 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-04-08

Study Completion Date

2019-07-23

Brief Summary

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Gene and protein bank to study disease modifying and susceptibility genes and proteins in urban patients with asthma.

Detailed Description

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Conditions

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Asthma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* Ages 18 and above

Exclusion Criteria

* Greater than 10 pack year tobacco history
* Lung diseases other than asthma
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joan Reibman, MD

Role: PRINCIPAL_INVESTIGATOR

NYU School of Medicine

Locations

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NYU School of Medicine

New York, New York, United States

Site Status

Countries

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United States

References

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Patrawalla P, Kazeros A, Rogers L, Shao Y, Liu M, Fernandez-Beros ME, Shang S, Reibman J. Application of the asthma phenotype algorithm from the Severe Asthma Research Program to an urban population. PLoS One. 2012;7(9):e44540. doi: 10.1371/journal.pone.0044540. Epub 2012 Sep 13.

Reference Type DERIVED
PMID: 23028556 (View on PubMed)

Liu M, Rogers L, Cheng Q, Shao Y, Fernandez-Beros ME, Hirschhorn JN, Lyon HN, Gajdos ZK, Vedantam S, Gregersen P, Seldin MF, Bleck B, Ramasamy A, Hartikainen AL, Jarvelin MR, Kuokkanen M, Laitinen T, Eriksson J, Lehtimaki T, Raitakari OT, Reibman J. Genetic variants of TSLP and asthma in an admixed urban population. PLoS One. 2011;6(9):e25099. doi: 10.1371/journal.pone.0025099. Epub 2011 Sep 22.

Reference Type DERIVED
PMID: 21966427 (View on PubMed)

Reibman J, Marmor M, Filner J, Fernandez-Beros ME, Rogers L, Perez-Perez GI, Blaser MJ. Asthma is inversely associated with Helicobacter pylori status in an urban population. PLoS One. 2008;3(12):e4060. doi: 10.1371/journal.pone.0004060. Epub 2008 Dec 29.

Reference Type DERIVED
PMID: 19112508 (View on PubMed)

Other Identifiers

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H9698

Identifier Type: -

Identifier Source: org_study_id

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