Factor V Leiden Mutation and Implantation Failure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

399 participants

Study Classification

OBSERVATIONAL

Study Start Date

2001-09-30

Study Completion Date

2005-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine whether inherited thrombophilias (tendency toward blood clotting) increase the risk of failure of the embryo to implant in IVF. The specific condition to be studied is the presence or absence of the Leiden mutation of the Factor V gene.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Determination of Performance Characteristics of the MassPLEX Factor II/V Leiden Test

NCT01835483

Factor V Leiden Factor II Thrombosis

COMPLETED

Cooperative Study of Factor VIII Inhibitors

NCT00000582

Blood Coagulation Disorders Hematologic Diseases Hemophilia A +1 more

COMPLETED PHASE3

Genetic Susceptibility to Factor VIII Inhibitors

NCT00344435

Hemophilia

COMPLETED

Mutation p.Ile112Thr : Discrepancy Between Factor IX Level and Bleeding Phenotype

NCT03946384

Hemophilia B

UNKNOWN

Severe Pregnancy Complications Are Associated With Elevated Factor VIII Plasma Activity

NCT00573118

Pregnancy Complications Preeclampsia Placental Abruption +2 more

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Infertility

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Test for Factor V Leiden gene mutation

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Women undergoing in-vitro fertilization with successful ovarian hyperstimulation, oocyte retrieval, and fertilization
* Transfer of at least 2 fresh embryos of Grade 2 (preembryo with blastomeres of equal size and \<=10% cytoplasmic fragmentation) or better

Exclusion Criteria

* Infertility due to uterine anatomic defect
* Current use of anticoagulant medication, such as heparin or aspirin
* Known presence of any other condition associated with increased risk of thrombosis

Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No