Magnetic Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia
NCT ID: NCT00186771
Last Updated: 2011-07-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
PHASE4
10 participants
INTERVENTIONAL
2004-11-30
2015-01-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Transcranial Magnetic Stimulation (TMS) can significantly reduce symptoms of schizophrenia. TMS is capable of inducing changes in the electrical activities of the brain in humans.
The purpose of this trial is to study the use of TMS to decrease auditory hallucinations in schizophrenia.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Repetitive Transcranial Magnetic Stimulation for Refractory Auditory Hallucinations in Schizophrenia
NCT01386918
rTMS Treatment for Positive and Negative Symptoms of Schizophrenia
NCT03413527
Transcranial Magnetic Stimulation (TMS) for Treatment of Auditory Hallucinations
NCT00763841
Transcranial Magnetic Stimulation for the Treatment of Auditory Hallucinations in Schizophrenia
NCT01595503
Transcranial Magnetic Stimulation (TMS) in Schizophrenia
NCT00564096
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
FMRI will highlight areas of activation with auditory hallucinations distinct from the area identified by Hoffman's scalp based method.
Cortical inhibition as measured by paired pulse TMS will be increased after true TMS but not sham TMS.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
True Transcranial Magnetic Stimulation
True treatment with TMS over the temporoparietal cortex.
Paired Pulse
True treatment with rTMS over the temporoparietal cortex.
Sham Transcranial Magnetic Stimulation
Sham treatment with rTMS over the temporoparietal cortex.
Paired Pulse
Sham treatment with rTMS over the temporoparietal cortex.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Paired Pulse
True treatment with rTMS over the temporoparietal cortex.
Paired Pulse
Sham treatment with rTMS over the temporoparietal cortex.
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Auditory hallucinations occuring more than 5 times per day
* Adequate (6 weeks) trial of antipsychotic medication
* Including at least 1 atypical antipsychotic medication
* Medication stable for 4 weeks prior to commencement of the study
* Competent to consent
Exclusion Criteria
* recent head injury
* Acute suicidality
* Alcohol or substance abuse
* Implanted pacemaker or metal in head or neck
* Pregnancy
18 Years
65 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
St. Joseph's Healthcare Hamilton
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
McMAster University
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Gary Hasey, MD
Role: PRINCIPAL_INVESTIGATOR
St. Joseph's Health Care London
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
St. Joseph's Healthcare, rTMS Laboratory, 100 West Fifth Street
Hamilton, Ontario, Canada
St. Joseph's Healthcare, rTMS Laboratory, 100 West Fifth Street
Hamilton, Ontario, Canada
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
TMS-2363
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.