Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

1999-11-30

Brief Summary

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Treatment for brain cancer may include radiation therapy. Radiation therapy is the treatment of tumors with X-rays. This study is related to understanding the side effects of radiation treatment for brain tumors.

This study is being conducted by the University of Rochester Cancer Center to compare the extent of side effects of brain cancer treatment with changes in levels of blood proteins called cytokines.

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Detailed Description

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Conditions

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Brain Neoplasm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Radiation Therapy

standard of care for the cancer being treated

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Any patient who will be treated to the brain or spinal axis for a CNS tum Patients so treated will be stratified according to whether or not the hypo is included in the treatment fields.
* Patients receiving external beam radiation to the brain may also be rece chemotherapy or interferon-beta. (Add. #1, 11-9-95)
* Patients receiving high dose rate (stereotactic radiosurgery) are eligible.
* Patients must sign a study specific informed consent meeting all federal a guidelines.
* Patients of any age, including children, are eligible (Add. #3, 11/25/97).