Mindfulness Meditation in Bone Marrow Transplantation

NCT ID: NCT00165282

Last Updated: 2013-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

241 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-04-30

Study Completion Date

2011-06-30

Brief Summary

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The main purpose of this study is to examine techniques to help patients cope better with the stem cell/bone marrow transplant procedure.

Detailed Description

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Patients will be assigned to one of three study groups:

1. receives the normal standard care;
2. meets with an oncology nurse educator, in addition to the regular nurses on the transplant team. The nurse educator will provide information and answers to patient's questions about the stem cell/bone marrow transplant experience; or
3. is taught mindfulness meditation by a nurse who is trained to be a mindfulness instructor and by an audio CD.

Mindfulness meditation is a technique that may help in coping with the stress and difficulties associated with cancer and undergoing a stem cell/bone marrow transplant. It involves learning to be in the present moment by paying attention to your breathing, sights, and sounds, and to sensations you may be experiencing, or thoughts and feelings you may be having.

Mindfulness meditation has been shown to be helpful to patients in the clinic who have cancer and other medical conditions.

Patients, regardless of random group assignment, will complete a questionnaire 8 different times, from before they are admitted to the hospital until 6 months after discharge.

Patients will also provide two urine samples while in the hospital to measure the levels of stress hormones present in the urine.

Conditions

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Hematologic Malignancy Bone Marrow Transplantation Stem Cell Transplantation

Keywords

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Meditation Mindfulness meditation Bone Marrow Transplant Stem Cell Transplant

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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Usual Care

Normal standard of care

Group Type NO_INTERVENTION

No interventions assigned to this group

Nurse education

Meets with oncology nurse

Group Type ACTIVE_COMPARATOR

Nurse education

Intervention Type BEHAVIORAL

Meets with oncology nurse to have questions answered about medical treatments and side effects

Mindfulness training

Taught Mindfulness meditation

Group Type EXPERIMENTAL

Mindfulness training

Intervention Type BEHAVIORAL

Taught mindfulness meditation by mindfulness instructor (trained health care professional/RN) and audio c/d

Interventions

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Mindfulness training

Taught mindfulness meditation by mindfulness instructor (trained health care professional/RN) and audio c/d

Intervention Type BEHAVIORAL

Nurse education

Meets with oncology nurse to have questions answered about medical treatments and side effects

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Autologous stem cell transplantation for hematologic malignancy
* First transplant
* 21 years of age or older
* Speaks and understands English

Exclusion Criteria

* Planned tandem (more than one) transplant
* Taking corticosteroids on a regular basis for a chronic condition
* Prior formal mindfulness meditation training
* Significant cognitive impairment and/or confirmed psychosis or thought disorder
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dana-Farber Cancer Institute

OTHER

Sponsor Role collaborator

University of Massachusetts, Worcester

OTHER

Sponsor Role collaborator

Emory University

OTHER

Sponsor Role lead

Responsible Party

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Susan Bauer-Wu, PhD, RN, FAAN

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Susan Bauer-Wu, PhD

Role: PRINCIPAL_INVESTIGATOR

Emory University

Locations

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Emory University

Atlanta, Georgia, United States

Site Status

Dana-Farber Cancer Institute

Boston, Massachusetts, United States

Site Status

University of Massachusetts Medical School

Worcester, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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IRB00005285

Identifier Type: -

Identifier Source: org_study_id