Predictive Value of Dynamic Contrast Enhancement MRI on a Cerebral Tumor Response to Gamma Knife Treatment

NCT ID: NCT00156585

Last Updated: 2015-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

31 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-08-31

Study Completion Date

2008-04-30

Brief Summary

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Hypothesis: the pattern of MRI contrast enhancement after gadolinium injection is different in tumors that respond well to gamma knife.

We are going to acquire sequential T1-weighted images of brain lesions before, during and after injection of Gd-DTPA. This will be repeated before and after a treatment with gamma knife. We will then analyse our results to see if there are common enhancement characteristics between lesions that will respond well to the radiosurgery treatment. Response will be clinically assessed by tumor volume as determined by MRI approximately 4 to 6 months after treatment.

Detailed Description

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Conditions

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Cerebral Metastases

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Exclusion Criteria

* Pancranial radiotherapy
* Residual postop lesion
* Gliomas
* Patients \< 18 years old
* Anterior allergic reaction to gadolinium
* Claustrophobia.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Martin Lepage

OTHER

Sponsor Role lead

Responsible Party

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Martin Lepage

MD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jean Chenard, MD

Role: PRINCIPAL_INVESTIGATOR

Université de Sherbrooke

Locations

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Faculté de médecine, Université de Sherbrooke

Sherbrooke, Quebec, Canada

Site Status

Countries

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Canada

Other Identifiers

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05-063

Identifier Type: -

Identifier Source: org_study_id

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