Psychodynamic Therapy For Co-occurring Borderline Personality Disorder and Alcohol Use Disorder

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-06-30

Study Completion Date

2010-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to determine the feasibility and effectiveness of a modified form of psychodynamic psychotherapy for persons suffering from co-occurring borderline personality disorder and an alcohol use disorder.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Modifying Group Therapy for Bipolar Substance Abusers - 1

NCT00227838

Bipolar Disorder Substance Dependence

COMPLETED NA

Group Therapy for Women Prisoners With Comorbid Substance Use and Depression

NCT00606996

Substance Abuse Substance Dependence Depressive Disorder

COMPLETED NA

Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD)

NCT01365247

Stress Disorders, Post-Traumatic Substance-Related Disorders

COMPLETED NA

Treatment Settings for Those With an Alcohol Problem

NCT02986776

Alcohol Abuse Alcohol-dependence

COMPLETED NA

Therapeutic Alliances in Alcoholism Treatment

NCT01689103

Alcohol Use Disorders

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Borderline Personality Disorder (BPD) is a condition that can cause significant distress and increased risk of death. Many persons with BPD also have an alcohol use disorder (AUD) and there is evidence that this can worsen the outcome and course of both disorders.

A manual-based form of psychodynamic therapy (PT), labeled dynamic deconstructive psychotherapy, has been developed for particularly challenging patients with BPD, especially those with co-occurring substance use disorders. It aims to remediate specific neurocognitive capacities that are responsible for processing of emotional experiences, and so diminishes symptoms of BPD and promotes the development of a coherent and differentiated self-structure. PT has been shown to be helpful for BPD, but has not been tested for people who have BPD with co-occurring substance use disorders.

The proposed study is a randomized controlled trial of PT for persons with BPD and co-occurring AUD that will generate some initial data that can be used to determine the need and feasibility for further outcome studies. Participants are randomized to either a study group receiving weekly PT or to a control group receiving usual care. Enrollment is 15 participants in each group. The study group will receive 12-18 months of PT, with naturalistic follow-up. Outcome measures are administered by a research assistant at enrollment, 3 months, 6 months, 9 months, 12 months, and 30 months.

The investigators anticipate that the PT group will show trends towards better retention in treatment and greater reduction in parasuicides, alcohol misuse, and institutional care. If so, this would have important and positive implications for the large group of patients who suffer from BPD and co-occurring AUD.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Borderline Personality Disorder Alcohol Use Disorder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

dynamic deconstructive psychotherapy

weekly individual psychotherapy of 50 minute duration lasting 12-18 months

Group Type EXPERIMENTAL

Psychodynamic Therapy

Intervention Type BEHAVIORAL

Dynamic deconstructive psychotherapy is a time-limited (12-18 month) manual-based form of psychodynamic therapy that aims to remediate specific neurocognitive capacities responsible for processing of emotional experiences.

optimized community care

eclectic weekly individual and group psychotherapy, as well as drug and alcohol rehabilitation

Group Type ACTIVE_COMPARATOR

Optimized Community Care

Intervention Type BEHAVIORAL

individual and group psychotherapy in a private practice, clinic, and/or rehab setting, with an eclectic orientation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.