Study Results
Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.
View full resultsBasic Information
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COMPLETED
NA
341 participants
INTERVENTIONAL
2005-11-30
2008-09-30
Brief Summary
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Detailed Description
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Methods:
During Phase I, baseline prevalence and natural history of OH will be determined by: enrolling consecutive appropriate subjects (able to stand, not end of life care) from a rehabilitation and nursing home unit and measuring OH 3 times weekly over their inpatient stay. In addition, chart review of diagnoses, medications, functional status, nutrition, and adverse events will be evaluated and correlated with clinical status. During Phase II, the investigators will implement a standardized, interdisciplinary (MD/RN/PT/Dietician) treatment plan for patients with OH. This will include chart review of diagnoses, medications, functional status, nutrition, adverse events, and correlation with clinical status. The goals of the interventions are to identify and treat the underlying causes of OH in rehabilitation patients. Based upon the comprehensive assessment, intervention participants will receive a standardized, interdisciplinary treatment regime.
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Treatment Phase 1
Stepped intervention consisting of treatment phase 1, 2 and 3. Subjects whose orthostatic hypotension is resolved after treatment phase 1 will not receive new treatments (phase 2 and 3)
Treatment Phase 1
* Patient Education
* Physical Therapy Exercises
* Increased Salt Intake
* Elevation of head of bed with 2-4 inch wedge
* Medication Review by MD, Pharma
Treatment Phase 2
Subjects receive Treatment Phase 2 if they are still orthostatic after receiving Treatment Phase 1.
* Fludrocortisone
* Salt tablet
Treatment Phase 3
Subjects still experiencing orthostatic hypotension after receiving Treatment Phases 1 and 2 move on to Treatment Phase 3. Individualized treatment is based on subspecialty or orthostatic hypotension consultation at the medical center. Subjects are followed for the duration of their hospital stay, on average 4 weeks.
Interventions
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Treatment Phase 1
* Patient Education
* Physical Therapy Exercises
* Increased Salt Intake
* Elevation of head of bed with 2-4 inch wedge
* Medication Review by MD, Pharma
Treatment Phase 2
Subjects receive Treatment Phase 2 if they are still orthostatic after receiving Treatment Phase 1.
* Fludrocortisone
* Salt tablet
Treatment Phase 3
Subjects still experiencing orthostatic hypotension after receiving Treatment Phases 1 and 2 move on to Treatment Phase 3. Individualized treatment is based on subspecialty or orthostatic hypotension consultation at the medical center. Subjects are followed for the duration of their hospital stay, on average 4 weeks.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Hospice admission
* Respite admission
18 Years
ALL
No
Sponsors
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VA Office of Research and Development
FED
Responsible Party
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Locations
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VA Portland Health Care System, Portland, OR
Portland, Oregon, United States
Countries
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Other Identifiers
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E3616-R
Identifier Type: -
Identifier Source: org_study_id
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