Assessment of Potential Interactions Between Cocaine and Tolcapone - 1

NCT ID: NCT00033059

Last Updated: 2017-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2001-07-31

Study Completion Date

2002-03-31

Brief Summary

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The purpose of this study is to assess the potential interactions between intravenous (IV) cocaine and tolcapone.

Detailed Description

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Double-blind, inpatient study by screening responses to cocaine infusions of 20 and 40 mg i.v. subjects into 1 of 2 treatment groups to assess potential interactions between i.v. cocaine infusion and treatment with tolcapone.

Conditions

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Cocaine-Related Disorders

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Tolcapone

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Volunteers dependent on cocaine and are non-treatment seeking; between 18-45 yrs of age; DSM-4 criteria for cocaine abuse or dependence

Exclusion Criteria

Additional criteria available during screening at the site
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role lead

Principal Investigators

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Thomas Newton, M.D.

Role: PRINCIPAL_INVESTIGATOR

National Institute on Drug Abuse (NIDA)

Locations

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UCLA Integrated Substance Abuse Program

Los Angeles, California, United States

Site Status

Countries

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United States

Other Identifiers

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NIDA-CTO-0003-1

Identifier Type: -

Identifier Source: org_study_id

NCT00024765

Identifier Type: -

Identifier Source: nct_alias

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