Non-Invasive Electrical Stimulation of the Human Brain

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

175 participants

Study Classification

OBSERVATIONAL

Study Start Date

1986-02-28

Study Completion Date

2001-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is designed to allow researchers to use transelectrical stimulation to explore the function of the human nervous system and improve diagnosis of neurological disorders.

Transcranial electrical stimulation is a non-invasive technique that can be used to stimulate brain activity and gather information about brain function. Electrical stimulation involves placing electrodes on the scalp or skin and passing an electrical current between them. When this is done, an electrical field is created that activates areas of the brain that control muscles. Muscle activity as a result of the stimulation can be recorded and analyzed.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effects of tDCS Over the Cerebellum on Motor Function

NCT00413842

Healthy

COMPLETED

Remotely Supervised tDCS for Slowing ALS Disease Progression

NCT04866771

Amyotrophic Lateral Sclerosis (ALS)

COMPLETED NA

Transcutaneous Vagal Nerve Stimulation: Influence on miRNA, Inflammation, Cerebral Resting State and Gastric Motility

NCT02359188

Epilepsy

COMPLETED PHASE1/PHASE2

The Effect of Transcutaneous Electrical Nerve Stimulation (TENS) in Multiple Sclerosis

NCT01280539

Multiple Sclerosis

COMPLETED NA

Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve

NCT05664854

Vagus Nerve Diseases Epilepsy Vagus Nerve Autonomic Disorder

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This protocol application is written to permit us to use transcranial electrical stimulation, a safe and noninvasive method for activating the brain, spinal cord, or proximal nerves through the skin, in appropriate subjects. We will use this technique to explore the function of the human central and peripheral nervous system and to aid in the diagnosis of neurological disorders.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cerebrovascular Disorders Healthy Nervous System Diseases Spinal Cord Injuries

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Males and females, ages 18 and over.

Diverse racial groups.

Amputees and others with whom we will have no patient-care relationship may also be considered to be volunteers.

Patients will be recruited from those referred to the Human Motor Control Section, NINDS who have neurological syndromes that are of interest.

On rare occasions we may attempt to study children as young as 10 years with TES.

Individuals without indwelling cardiac lines and pacemakers.

Patients recruited for study would come from those referred to the EMG laboratory and to the Human Motor Control Clinic who would have distinct neurologic syndromes from well defined peripheral and central nervous system lesions including hemiplegia from stroke, trauma, tumor or focal demyelination (most commonly patients would have hemiplegia from stroke), peripheral nerve lesions, amputations, spinal cord injury.

Normal volunteers, including NIH employees, would be healthy adults without history of physical examination evidence of neurologic disease and individuals with different types of amputations involving upper and lower extremities.

Volunteers may also be participants in the electrophysiological protocol (84-N-0196).

No history of epilepsy.

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes