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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07006727 | RECRUITING | PHASE1
116 Participants

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-16
Completion: 2031-06-17
Conditions
Small Cell Lung Carcinoma Large Cell Neuroendocrine Carcinoma of the Lung Neuroendocrine Prostate Cancer Gastroenteropancreatic Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
NCT07001748 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
148 Participants

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-08-19
Completion: 2030-05-30
Conditions
Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Peritoneal Carcinomatosis
Interventions
DRUG PROCEDURE
No Results Yet
NCT07000760 | RECRUITING | PHASE4
240 Participants

Intraoperative Ultrasonic Atomization of Lidocaine and Postoperative Pulmonary Complications

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-06
Completion: 2025-12-06
Conditions
Postoperative Pulmonary Complications (PPCs)
Interventions
DRUG
No Results Yet
NCT06996548 | COMPLETED
120 Participants

Sarcopenia and Paclitaxel-Induced Neuropathy in Early Stage Breast Cancer (Neuro-Sarc)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-11-01
Completion: 2025-05-06
Conditions
Sarcopenia Paclitaxel Induced Neuropathy Breast Carcinoma
No Results Yet
NCT06993480 | RECRUITING | PHASE2
30 Participants

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-18
Completion: 2026-06-30
Conditions
Chronic Hepatitis B
Interventions
DRUG
No Results Yet
NCT06992661 | RECRUITING | PHASE1
84 Participants

A Study of the Pharmacokinetics and Safety of Single-dose Inhaled ICF004 in Healthy Volunteers and Patients With Interstitial Lung Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-20
Completion: 2026-07-01
Conditions
Interstitial Lung Disease (ILD) Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06985953 | RECRUITING | NA
30 Participants

Evaluating the Communication Between Patients and Providers in Cancer Clinics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-31
Completion: 2027-01-31
Conditions
Cancer
Interventions
OTHER
No Results Yet
NCT06984796 | NOT_YET_RECRUITING | NA
72 Participants

Photobiomodulation on Pain Perception During the Insertion of the T 380 Copper Intrauterine Device (IUD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-30
Completion: 2026-11-30
Conditions
Pain
Interventions
DEVICE OTHER
No Results Yet
NCT06975657 | NOT_YET_RECRUITING | NA
60 Participants

Well-being Skills for Reentry

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-01
Completion: 2027-11-30
Conditions
Formerly Incarcerated Adults
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT06974630 | COMPLETED | NA
40 Participants

Cervical Erector Spinae Plane Block vs Cervical Plexus Block in Controlling Acute Postoperative Pain After Thyroidectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-15
Completion: 2025-11-30
Conditions
Cervical Erector Spinae Plane Block Cervical Plexus Block Postoperative Pain Thyroidectomy
Interventions
OTHER
No Results Yet
NCT06973447 | COMPLETED | NA
30 Participants

Combined ASSNB and ICBPB vs CCBPB in Shoulder Arthroscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-01-30
Completion: 2025-09-30
Conditions
Postoperative Pain Shoulder Arthroscopy
Interventions
PROCEDURE
No Results Yet
NCT06966258 | RECRUITING | NA
90 Participants

Inspire HER: Inspiring the Heart and Emotions for Radical Health

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-11-15
Completion: 2029-01-31
Conditions
Kidney Disease Obesity Smoking Cardiovascular-kidney-metabolic Syndrome Cardiovascular Diseases Hypertension Diabetes Hyperlipidemia
Interventions
BEHAVIORAL
No Results Yet
NCT06963827 | RECRUITING | PHASE3
347 Participants

A Study of Mezagitamab in Adults With Primary IgA Nephropathy Kidney Condition

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-15
Completion: 2028-09-07
Conditions
Kidney Disease
Interventions
DRUG
No Results Yet
NCT06961344 | ENROLLING_BY_INVITATION | PHASE2
44 Participants

An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-08-18
Completion: 2028-07-31
Conditions
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Interventions
DRUG
No Results Yet
NCT06950385 | RECRUITING | PHASE3
168 Participants

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-18
Completion: 2030-07-31
Conditions
Familial Adenomatous Polyposis (FAP)
Interventions
DRUG
No Results Yet
NCT06948578 | COMPLETED | NA
34 Participants

Thread-Embedding Acupuncture for Functional and QoL Improvement in COPD Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-01
Completion: 2025-11-30
Conditions
Chronic Pulmonary Obstruction
Interventions
DEVICE
No Results Yet
NCT06921473 | COMPLETED | PHASE4
102 Participants

Effect of Ephedrine vs. Norepinephrine on Prevention of Fetal Acidosis During Cesarean Section Under Spinal Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-01
Completion: 2025-12-12
Conditions
Cesarean Delivery Affecting Newborn Acidosis Maternal Hypotension Spinal Aneshtesia
Interventions
DRUG
No Results Yet
NCT06908499 | NOT_YET_RECRUITING
840 Participants

The DECISION-CTO Extended 10 Y Follow-up

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2026-04-01
Completion: 2026-04-30
Conditions
Coronary Artery Disease
No Results Yet
NCT06899230 | ACTIVE_NOT_RECRUITING | PHASE1
72 Participants

Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of iQ-007

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-04-08
Completion: 2026-01-29
Conditions
Drug Resistant Epilepsy Focal Seizure
Interventions
DRUG
No Results Yet
NCT06889389 | RECRUITING | NA
81 Participants

Effects of Education and Exercise on Pain, Psychosocial Factors, and Upper Limb Function in Non-specific Neck Pain.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-03-28
Completion: 2026-10-30
Conditions
Neck Pain Patient Education Exercise Therapy Fear Pain
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06882135 | RECRUITING | PHASE1
76 Participants

HW071021 Monotherapy in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-28
Completion: 2026-09-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06881823 | WITHDRAWN | PHASE1/PHASE2
0 Participants

Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-06-29
Completion: 2030-03-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06874894 | ENROLLING_BY_INVITATION
1021 Participants

Thromboembolic And Bleeding Risks During anticoaGulant trEatment in Asian paTients With Atrial Fibrillation (TARGET-AF)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2022-05-25
Completion: 2026-08-30
Conditions
Fibrillation, Atrial
No Results Yet
NCT06865027 | ENROLLING_BY_INVITATION | NA
46 Participants

The Effect of Arterial Carbon Dioxide Levels on Cerebral Blood Flow and Cerebral Autoregulation in the Steep Trendelenburg Position During Robot-assisted Prostatectomy, and Its Effect on Postoperative Cognition

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-24
Completion: 2026-06-30
Conditions
Cognitive Function Intracranial Pressure Circulation System Cerebral Perfusion Pressure
Interventions
OTHER
No Results Yet
NCT06864169 | RECRUITING | PHASE2
160 Participants

A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-04-01
Completion: 2026-07-06
Conditions
Gastrointestinal Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06844630 | COMPLETED | NA
60 Participants

Interscalene vs Infraspinatus-teres Minor (ITM) Interfascial Block in Shoulder Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-03-01
Completion: 2025-06-30
Conditions
Shoulder Pain Pain, Postoperative Surgical Procedure, Unspecified
Interventions
OTHER
No Results Yet
NCT06841536 | ACTIVE_NOT_RECRUITING | NA
120 Participants

Combined Effects of Statins and Exercise on Training Sensitive Health Markers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-01
Completion: 2025-12-16
Conditions
Dyslipidemias
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT06834100 | RECRUITING | PHASE3
240 Participants

Assessment of Immunogenicity, Reactogenicity and Safety of the Drug GNG-DE in Comparison With the Reference Drug

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-02-12
Completion: 2025-12-31
Conditions
Infections Meningococcal
Interventions
DRUG
No Results Yet
NCT06820099 | RECRUITING | PHASE2
225 Participants

Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-04-10
Completion: 2026-12-31
Conditions
Adults With Heart Failure, Mild Decrease in Ejection Fraction/Preserved Ejection Fraction, and Obesity
Interventions
DRUG
No Results Yet
NCT06819865 | NOT_YET_RECRUITING
30 Participants

A Real-World Study of EkoSonic Endovascular System in Chinese Populations With Acute Pulmonary Embolism

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2026-02-28
Completion: 2027-03-30
Conditions
Acute Pulmonary Embolism
Interventions
DEVICE
No Results Yet
NCT06816485 | RECRUITING | NA
93 Participants

INFLATE Study: Investigation of the Safety and Performance of a Novel PTV Balloon in Patients Undergoing TAVI for Severe Aortic Stenosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-15
Completion: 2026-08-31
Conditions
Aortic Diseases
Interventions
DEVICE
No Results Yet
NCT06811285 | COMPLETED | NA
97 Participants

Kinesio Taping and Foot Massage for Post-Cesarean Recovery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-12-02
Completion: 2025-04-18
Conditions
Pain Fatigue Mood (Psychological Function) Postpartum Women
Interventions
OTHER
No Results Yet
NCT06810310 | RECRUITING | PHASE2
24 Participants

Psilocybin on Brain Mechanisms of Motivation in OUD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-22
Completion: 2026-05-01
Conditions
Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT06808217 | RECRUITING
500 Participants

A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System When Used With the FARAWAVE NAV Ablation Catheter in the Treatment of Atrial Fibrillation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-30
Completion: 2026-08-01
Conditions
Atrial Fibrillation Pulsed Field Ablation FARAPULSE
Interventions
DEVICE
No Results Yet
NCT06801236 | RECRUITING | PHASE1
67 Participants

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-12
Completion: 2028-03-01
Conditions
Prostate Cancer (Adenocarcinoma) mCRPC (Metastatic Castration-resistant Prostate Cancer)
Interventions
DRUG
No Results Yet
NCT06796894 | RECRUITING
60 Participants

Symptoms, Respiratory Dysfunction and Frailty Level in Allergic and Eosonophilic Asthmatics

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-01
Completion: 2026-10-30
Conditions
Asthma Respiratory Disease Fragility
No Results Yet
NCT06793670 | RECRUITING | PHASE4
1500 Participants

Landiolol in Mitral Valve Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-28
Completion: 2027-06-30
Conditions
Cardiac Failure Low Cardiac Output Syndrome
Interventions
DRUG
No Results Yet
NCT06784531 | ACTIVE_NOT_RECRUITING | NA
30 Participants

The Influence of Race and MitoQ Supplementation on Skin Blood Flow in the Cold

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-09-16
Completion: 2025-10-28
Conditions
Cold Exposure
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06784349 | ACTIVE_NOT_RECRUITING | PHASE1
32 Participants

ALN-APOC3 in Adult Participants With Dyslipidemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-27
Completion: 2026-02-25
Conditions
Dyslipidemia
Interventions
DRUG
No Results Yet
NCT06764615 | RECRUITING | PHASE2
183 Participants

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-28
Completion: 2029-12-30
Conditions
Crohn's Disease Ulcerative Colitis
Interventions
DRUG
No Results Yet
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