Clinical Trials Updated in 2025

NCT06975657 | NOT_YET_RECRUITING | NA

60 Participants

Well-being Skills for Reentry

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2026-01-01

Completion: 2027-11-30

Conditions

Formerly Incarcerated Adults

Interventions

BEHAVIORAL DEVICE

No Results Yet

NCT06974630 | COMPLETED | NA

40 Participants

Cervical Erector Spinae Plane Block vs Cervical Plexus Block in Controlling Acute Postoperative Pain After Thyroidectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-05-15

Completion: 2025-11-30

Conditions

Cervical Erector Spinae Plane Block Cervical Plexus Block Postoperative Pain Thyroidectomy

Interventions

OTHER

No Results Yet

NCT06973447 | COMPLETED | NA

30 Participants

Combined ASSNB and ICBPB vs CCBPB in Shoulder Arthroscopy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2024-01-30

Completion: 2025-09-30

Conditions

Postoperative Pain Shoulder Arthroscopy

Interventions

PROCEDURE

No Results Yet

NCT06966258 | RECRUITING | NA

90 Participants

Inspire HER: Inspiring the Heart and Emotions for Radical Health

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-11-15

Completion: 2029-01-31

Conditions

Kidney Disease Obesity Smoking Cardiovascular-kidney-metabolic Syndrome Cardiovascular Diseases Hypertension Diabetes Hyperlipidemia

Interventions

BEHAVIORAL

No Results Yet

NCT06963827 | RECRUITING | PHASE3

347 Participants

A Study of Mezagitamab in Adults With Primary IgA Nephropathy Kidney Condition

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-07-15

Completion: 2028-09-07

Conditions

Kidney Disease

Interventions

DRUG

No Results Yet

NCT06961344 | ENROLLING_BY_INVITATION | PHASE2

44 Participants

An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-08-18

Completion: 2028-07-31

Conditions

Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

Interventions

DRUG

No Results Yet

NCT06950385 | RECRUITING | PHASE3

168 Participants

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-07-18

Completion: 2030-07-31

Conditions

Familial Adenomatous Polyposis (FAP)

Interventions

DRUG

No Results Yet

NCT06948578 | COMPLETED | NA

34 Participants

Thread-Embedding Acupuncture for Functional and QoL Improvement in COPD Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-07-01

Completion: 2025-11-30

Conditions

Chronic Pulmonary Obstruction

Interventions

DEVICE

No Results Yet

NCT06921473 | COMPLETED | PHASE4

102 Participants

Effect of Ephedrine vs. Norepinephrine on Prevention of Fetal Acidosis During Cesarean Section Under Spinal Anesthesia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-09-01

Completion: 2025-12-12

Conditions

Cesarean Delivery Affecting Newborn Acidosis Maternal Hypotension Spinal Aneshtesia

Interventions

DRUG

No Results Yet

NCT06908499 | NOT_YET_RECRUITING

840 Participants

The DECISION-CTO Extended 10 Y Follow-up

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2026-04-01

Completion: 2026-04-30

Conditions

Coronary Artery Disease

No Results Yet

NCT06899230 | ACTIVE_NOT_RECRUITING | PHASE1

72 Participants

Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of iQ-007

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-04-08

Completion: 2026-01-29

Conditions

Drug Resistant Epilepsy Focal Seizure

Interventions

DRUG

No Results Yet

NCT06889389 | RECRUITING | NA

81 Participants

Effects of Education and Exercise on Pain, Psychosocial Factors, and Upper Limb Function in Non-specific Neck Pain.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-03-28

Completion: 2026-10-30

Conditions

Neck Pain Patient Education Exercise Therapy Fear Pain

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06882135 | RECRUITING | PHASE1

76 Participants

HW071021 Monotherapy in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-05-28

Completion: 2026-09-30

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06881823 | WITHDRAWN | PHASE1/PHASE2

0 Participants

Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2026-06-29

Completion: 2030-03-31

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06874894 | ENROLLING_BY_INVITATION

1021 Participants

Thromboembolic And Bleeding Risks During anticoaGulant trEatment in Asian paTients With Atrial Fibrillation (TARGET-AF)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2022-05-25

Completion: 2026-08-30

Conditions

Fibrillation, Atrial

No Results Yet

NCT06865027 | ENROLLING_BY_INVITATION | NA

46 Participants

The Effect of Arterial Carbon Dioxide Levels on Cerebral Blood Flow and Cerebral Autoregulation in the Steep Trendelenburg Position During Robot-assisted Prostatectomy, and Its Effect on Postoperative Cognition

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-01-24

Completion: 2026-06-30

Conditions

Cognitive Function Intracranial Pressure Circulation System Cerebral Perfusion Pressure

Interventions

OTHER

No Results Yet

NCT06864169 | RECRUITING | PHASE2

160 Participants

A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-04-01

Completion: 2026-07-06

Conditions

Gastrointestinal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06844630 | COMPLETED | NA

60 Participants

Interscalene vs Infraspinatus-teres Minor (ITM) Interfascial Block in Shoulder Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-03-01

Completion: 2025-06-30

Conditions

Shoulder Pain Pain, Postoperative Surgical Procedure, Unspecified

Interventions

OTHER

No Results Yet

NCT06841536 | ACTIVE_NOT_RECRUITING | NA

120 Participants

Combined Effects of Statins and Exercise on Training Sensitive Health Markers

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-05-01

Completion: 2025-12-16

Conditions

Dyslipidemias

Interventions

DRUG BEHAVIORAL

No Results Yet

NCT06834100 | RECRUITING | PHASE3

240 Participants

Assessment of Immunogenicity, Reactogenicity and Safety of the Drug GNG-DE in Comparison With the Reference Drug

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-02-12

Completion: 2025-12-31

Conditions

Infections Meningococcal

Interventions

DRUG

No Results Yet

NCT06820099 | RECRUITING | PHASE2

225 Participants

Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-04-10

Completion: 2026-12-31

Conditions

Adults With Heart Failure, Mild Decrease in Ejection Fraction/Preserved Ejection Fraction, and Obesity

Interventions

DRUG

No Results Yet

NCT06819865 | NOT_YET_RECRUITING

30 Participants

A Real-World Study of EkoSonic Endovascular System in Chinese Populations With Acute Pulmonary Embolism

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2026-02-28

Completion: 2027-03-30

Conditions

Acute Pulmonary Embolism

Interventions

DEVICE

No Results Yet

NCT06816485 | RECRUITING | NA

93 Participants

INFLATE Study: Investigation of the Safety and Performance of a Novel PTV Balloon in Patients Undergoing TAVI for Severe Aortic Stenosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-12-15

Completion: 2026-08-31

Conditions

Aortic Diseases

Interventions

DEVICE

No Results Yet

NCT06811285 | COMPLETED | NA

97 Participants

Kinesio Taping and Foot Massage for Post-Cesarean Recovery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2024-12-02

Completion: 2025-04-18

Conditions

Pain Fatigue Mood (Psychological Function) Postpartum Women

Interventions

OTHER

No Results Yet

NCT06810310 | RECRUITING | PHASE2

24 Participants

Psilocybin on Brain Mechanisms of Motivation in OUD

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-12-22

Completion: 2026-05-01

Conditions

Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT06808217 | RECRUITING

500 Participants

A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System When Used With the FARAWAVE NAV Ablation Catheter in the Treatment of Atrial Fibrillation

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2025-07-30

Completion: 2026-08-01

Conditions

Atrial Fibrillation Pulsed Field Ablation FARAPULSE

Interventions

DEVICE

No Results Yet

NCT06801236 | RECRUITING | PHASE1

67 Participants

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-05-12

Completion: 2028-03-01

Conditions

Prostate Cancer (Adenocarcinoma) mCRPC (Metastatic Castration-resistant Prostate Cancer)

Interventions

DRUG

No Results Yet

NCT06796894 | RECRUITING

60 Participants

Symptoms, Respiratory Dysfunction and Frailty Level in Allergic and Eosonophilic Asthmatics

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2024-08-01

Completion: 2026-10-30

Conditions

Asthma Respiratory Disease Fragility

No Results Yet

NCT06793670 | RECRUITING | PHASE4

1500 Participants

Landiolol in Mitral Valve Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-01-28

Completion: 2027-06-30

Conditions

Cardiac Failure Low Cardiac Output Syndrome

Interventions

DRUG

No Results Yet

NCT06784531 | ACTIVE_NOT_RECRUITING | NA

30 Participants

The Influence of Race and MitoQ Supplementation on Skin Blood Flow in the Cold

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2024-09-16

Completion: 2025-10-28

Conditions

Cold Exposure

Interventions

DIETARY_SUPPLEMENT OTHER

No Results Yet

NCT06784349 | ACTIVE_NOT_RECRUITING | PHASE1

32 Participants

ALN-APOC3 in Adult Participants With Dyslipidemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-01-27

Completion: 2026-02-25

Conditions

Dyslipidemia

Interventions

DRUG

No Results Yet

NCT06764615 | RECRUITING | PHASE2

183 Participants

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-05-28

Completion: 2029-12-30

Conditions

Crohn's Disease Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT06756607 | RECRUITING | NA

500 Participants

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-04-25

Completion: 2028-08-01

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT06753877 | COMPLETED | NA

200 Participants

Clinical Monitoring Using ICF

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2024-06-01

Completion: 2024-10-01

Conditions

Stroke

Interventions

BEHAVIORAL

No Results Yet

NCT06751238 | RECRUITING | PHASE1

20 Participants

Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-09-24

Completion: 2032-11-30

Conditions

Juvenile Psoriatic Arthritis

Interventions

BIOLOGICAL

No Results Yet

NCT06738368 | NOT_YET_RECRUITING | PHASE2

30 Participants

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2026-01-01

Completion: 2028-01-31

Conditions

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative T Acute Lymphoblastic Leukemia

Interventions

DRUG PROCEDURE BIOLOGICAL

No Results Yet

NCT06735430 | COMPLETED | NA

86 Participants

Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-03-09

Completion: 2025-08-31

Conditions

Pediatric Hernia Laparoscopic Surgery Appendicitis, Surgery

Interventions

DRUG

No Results Yet

NCT06734611 | NOT_YET_RECRUITING | NA

250 Participants

Folic Acid Salt Study (FISFA Zambia)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2026-03-01

Completion: 2026-12-31

Conditions

Folate Deficiency Neural Tube Defects

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06734104 | COMPLETED | NA

60 Participants

The Effect of an Interactive Video on Nursing Students' Learning in the Care of Anti-Embolism Stockings

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2024-12-13

Completion: 2024-12-20

Conditions

Nursing Students Nursing Education Surgical Nursing

Interventions

OTHER

No Results Yet

NCT06724575 | ACTIVE_NOT_RECRUITING

154 Participants

EVOLVE Study: The Real-life Clinical Practice With Tezepelumab in Greece

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2024-12-17

Completion: 2028-06-30

Conditions

Asthma

No Results Yet