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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05524571 | ACTIVE_NOT_RECRUITING | PHASE3
100 Participants

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-01-05
Completion: 2026-03-31
Conditions
Thyroid Eye Disease
Interventions
DRUG
No Results Yet
NCT05521503 | RECRUITING
400 Participants

Biopsy Collection and Repository Database

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-12-21
Completion: 2030-12-31
Conditions
Cardiovascular Diseases
No Results Yet
NCT05520099 | RECRUITING
416 Participants

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-26
Completion: 2027-01-31
Conditions
Immunotherapy Cancer Bladder Cancer Urothelial Carcinoma Bladder Kidney Cancer Clear Cell Renal Cell Cancer (ccRCC) Colorectal Cancer MSI-H Colorectal Cancer DMMR Colorectal Cancer Head and Neck Cancer (H&N) Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) Liver Cancer Hepatocellular Carcinoma (HCC) Lung Cancer (NSCLC) NSCLC (Non-small Cell Lung Cancer) Skin Cancer Cutaneous Melanoma Endometrial Cancer Solid Tumor Cancer
Interventions
PROCEDURE
No Results Yet
NCT05499884 | COMPLETED | NA
10 Participants

Feasibility and Potential Aids of Intra-operative Endo-vaginal Ultrasound When Performing Rectal Shaving for Endometriosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-03
Completion: 2024-07-15
Conditions
Endometriosis
Interventions
PROCEDURE
No Results Yet
NCT05494632 | COMPLETED | NA
45 Participants

Interaural Frequency and Loudness Mismatch in SSD CI Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-12
Completion: 2024-07-30
Conditions
Outcomes
Interventions
DEVICE
Results Available
NCT05491018 | NOT_YET_RECRUITING
13270 Participants

Performance for French Pediatric Intensive Care Units

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-31
Completion: 2027-10-31
Conditions
Severity of Illness Index
No Results Yet
NCT05490446 | ACTIVE_NOT_RECRUITING | PHASE2
87 Participants

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-07
Completion: 2026-03-31
Conditions
Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT05484141 | NOT_YET_RECRUITING | NA
34 Participants

The Effect of Blood Flow Restriction Method in Patellar Instability

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-01
Completion: 2026-12-01
Conditions
Patellar Abnormality
Interventions
OTHER
No Results Yet
NCT05480449 | RECRUITING | PHASE1/PHASE2
89 Participants

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-20
Completion: 2027-09-20
Conditions
B Cell Acute Lymphoblastic Leukemia (B-ALL) B Lineage Lymphoblastic Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT05477953 | NOT_YET_RECRUITING
50 Participants

An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2026-06-30
Completion: 2032-01-31
Conditions
Chagas Disease
Interventions
DRUG
No Results Yet
NCT05468502 | COMPLETED | PHASE1
17 Participants

Phase I/IIa Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-10-10
Completion: 2025-08-01
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT05465941 | RECRUITING | PHASE2
43 Participants

PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-14
Completion: 2027-05-15
Conditions
Platinum-Resistant Fallopian Tube Carcinoma Platinum-Resistant Ovarian Carcinoma Platinum-Resistant Primary Peritoneal Carcinoma Stage IV Fallopian Tube Cancer AJCC v8 Stage IV Ovarian Cancer AJCC v8 Stage IV Primary Peritoneal Cancer AJCC v8
Interventions
PROCEDURE DRUG
No Results Yet
NCT05464758 | COMPLETED | NA
16 Participants

The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-01
Completion: 2024-09-13
Conditions
Cold Exposure
Interventions
OTHER
No Results Yet
NCT05458960 | TERMINATED | NA
3 Participants

Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-28
Completion: 2025-08-28
Conditions
Cervical Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05457166 | RECRUITING | NA
40 Participants

Use of the KASPARD System for Fall Prevention in Nursing Homes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-07-07
Completion: 2026-10-31
Conditions
Accidental Falls Nursing Homes
Interventions
DEVICE
No Results Yet
NCT05455359 | RECRUITING | PHASE4
120 Participants

Gastrointestinal Dysmotility on Aspiration Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-13
Completion: 2027-05-31
Conditions
Esophageal Motility Disorders Gastric Motor Dysfunction Aspiration Pneumonia Gastro Esophageal Reflux
Interventions
DRUG
No Results Yet
NCT05454657 | COMPLETED | NA
120 Participants

Heart Rate Variability Biofeedback for Substance Use Disorder: A Randomized Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-01-04
Completion: 2024-09-15
Conditions
Substance Use Disorders
Interventions
DEVICE BEHAVIORAL
Results Available
NCT05454475 | COMPLETED
270 Participants

Effect of Different Water Injection Temperatures on the Safety and Comfort of Patients Undergoing Ultrasound Endoscopy of Small Probes Under Intravenous Anesthesia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-06-14
Completion: 2023-05-01
Conditions
Small Probe Ultrasound Endoscopy The Water Temperature
Interventions
OTHER
No Results Yet
NCT05454202 | COMPLETED
20 Participants

Assessment of the Interest of ANI in the Non-communicating Patient in Palliative Care

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-22
Completion: 2024-05-24
Conditions
End of Life Pain Analgesia
Interventions
DEVICE
No Results Yet
NCT05447078 | COMPLETED | PHASE3
492 Participants

Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-07-01
Completion: 2025-12-08
Conditions
Healthy Volunteers
Interventions
DRUG DIETARY_SUPPLEMENT
No Results Yet
NCT05413304 | RECRUITING | PHASE1
17 Participants

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-07
Completion: 2025-12-31
Conditions
Glioma
Interventions
DRUG DEVICE
No Results Yet
NCT05413005 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
10 Participants

Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Type 1 Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-05
Completion: 2026-09-01
Conditions
Type 1 Diabetes
Interventions
BIOLOGICAL COMBINATION_PRODUCT
No Results Yet
NCT05406037 | RECRUITING
100 Participants

Biomarkers for Invasive Mucormycosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-29
Completion: 2026-07-31
Conditions
Mucorales Infection Mucormycosis
Interventions
BIOLOGICAL
No Results Yet
NCT05405491 | ACTIVE_NOT_RECRUITING | NA
31 Participants

Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-28
Completion: 2028-03-31
Conditions
Pneumonia, Ventilator-Associated Pneumonia, Hospital-Acquired Immunodeficiency
Interventions
OTHER
No Results Yet
NCT05403866 | COMPLETED | PHASE2
89 Participants

A Study to Evaluate the Safety and Efficacy of Multiple Doses of LT3001 Drug Product in AIS Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-17
Completion: 2025-05-23
Conditions
Acute Ischemic Stroke
Interventions
DRUG
Results Available
NCT05400603 | RECRUITING | PHASE1
24 Participants

Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-06
Completion: 2026-12-31
Conditions
Neuroblastoma Refractory Neuroblastoma Relapsed Neuroblastoma Relapsed Osteosarcoma Refractory Osteosarcoma
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05392556 | COMPLETED | NA
73 Participants

Prebiotic and Probiotic Modulation of the Gut Microbiota-gut-brain Axis During Acute Stress

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-07-06
Completion: 2025-10-28
Conditions
Stress Physiology
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT05375812 | RECRUITING
85 Participants

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-16
Completion: 2030-12-31
Conditions
Gulf War Illness
No Results Yet
NCT05357742 | COMPLETED | NA
50 Participants

Basic Needs Navigation Intervention to Address Multidimensional Adversity in African Americans With Diabetic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-01
Completion: 2025-07-31
Conditions
Diabetic Nephropathies Diabetes Mellitus, Type 2 Chronic Kidney Diseases Healthy Lifestyle
Interventions
BEHAVIORAL
No Results Yet
NCT05353153 | COMPLETED | NA
60 Participants

The Psychological Experience of Pathological Pregnancy. Study of the Case of Premature Rupture of Membranes and Evaluation of the Impact of Hypnosis Support

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-06-03
Completion: 2025-01-10
Conditions
Preterm Premature Rupture of Membrane
Interventions
OTHER
No Results Yet
NCT05348876 | RECRUITING | PHASE4
50 Participants

A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-03
Completion: 2026-01-28
Conditions
Non-metastatic Castration-resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT05327270 | ACTIVE_NOT_RECRUITING | PHASE1
18 Participants

Non-randomized, Open-label Study of Intralesional Nivolumab for High Risk Oral Premalignant Lesions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-13
Completion: 2027-02-02
Conditions
Head and Neck Cancer
Interventions
DRUG
No Results Yet
NCT05324358 | COMPLETED | PHASE3
341 Participants

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-12-14
Completion: 2024-09-06
Conditions
Pain, Postoperative
Interventions
DRUG OTHER
No Results Yet
NCT05304091 | WITHDRAWN
0 Participants

Characterization of Rhythmicity Profiles of Bradykinin-mediated Angioedema Attacks Using a Tracking Smartphone Application.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-31
Completion: 2023-08-31
Conditions
Bradykinin-mediated Angioedema
Interventions
OTHER
No Results Yet
NCT05304065 | RECRUITING | PHASE2
1600 Participants

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-10-17
Completion: 2026-12-31
Conditions
Suicide and Self-harm
Interventions
BEHAVIORAL
No Results Yet
NCT05303467 | RECRUITING | PHASE1
36 Participants

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-07-30
Completion: 2026-03-31
Conditions
Glioblastoma Multiforme Recurrent Glioblastoma
Interventions
DEVICE
No Results Yet
NCT05295095 | RECRUITING | NA
264 Participants

Does Positive Pressure Extubation Reduce Postoperative Desaturation?

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-06-29
Completion: 2026-06-30
Conditions
Extubation Postoperative Complications Lung Ultrasound Score
Interventions
PROCEDURE
No Results Yet
NCT05281835 | RECRUITING
1000 Participants

Follow-up of Elderly Subjects With Falls Recruited in the Geriatric Departments of Several French Hospitals

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-06-16
Completion: 2026-03-31
Conditions
Falls in the Elderly
No Results Yet
NCT05279170 | RECRUITING | NA
72 Participants

MAsk VEntilation With Paratracheal Pressure In Children. Para Tracheal Compression to Prevent Gastric Insufflation in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-06
Completion: 2027-06-30
Conditions
Surgery Anesthesia Intubation Complication
Interventions
OTHER
No Results Yet
NCT05278741 | ACTIVE_NOT_RECRUITING | NA
32 Participants

Functional Evaluation After Breast Reconstruction With a Minimally Invasive Latissimus Dorsi Flap Following Radical Surgery for Breast Cancer.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-25
Completion: 2026-03-06
Conditions
Breast Cancer
Interventions
PROCEDURE
No Results Yet
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