Clinical Trials
Showing trials with last updates posted in 2025.
67
Participants
A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children Aged 2-17 Years With CAH
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-10
Completion:
2025-01-31
Conditions
Congenital Adrenal Hyperplasia
21-OHD
Interventions
DRUG
2606
Participants
Facing Adverse Childhood Experiences
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-10-28
Completion:
2024-05-01
Conditions
Adverse Childhood Experiences
No Results Yet
20
Participants
Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-08-12
Completion:
2026-01-01
Conditions
Chronic Granulomatous Disease
Inflammatory Gastrointestinal Disease
Inflammatory Skin Disease
Inflammatory Lung Disease
Interventions
DRUG
No Results Yet
68
Participants
Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-21
Completion:
2026-12-31
Conditions
Non-Hodgkin Lymphoma
B-cell Non-Hodgkin Lymphoma (B-NHL)
Mantle Cell Lymphoma (MCL)
CNS Lymphoma
Interventions
DRUG
No Results Yet
150
Participants
A Comprehensive Community Approach for Diabetes Prevention and Care for a Vulnerable Population in Galveston
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-07
Completion:
2025-10-31
Conditions
Diabetes Mellitus, Type 2
Interventions
OTHER
No Results Yet
136
Participants
A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-03-02
Completion:
2026-12-31
Conditions
Relapsing-Remitting Multiple Sclerosis
Interventions
DRUG
No Results Yet
1314
Participants
A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-08-25
Completion:
2027-08-01
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
93
Participants
A Study to Evaluate the Efficacy and Safety of CYH33 in Patients With Recurrent/Persistent Ovary Clear Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-10-11
Completion:
2024-07-31
Conditions
Ovarian Cancer
Recurrent Cancer
Interventions
DRUG
No Results Yet
10
Participants
Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-08-01
Completion:
2030-10-12
Conditions
Hereditary Transthyretin-mediated (hATTR) Amyloidosis
Polyneuropathy
No Results Yet
128
Participants
A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-10-08
Completion:
2025-11-13
Conditions
Locally Advanced or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
75
Participants
The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral Artery Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-04-19
Completion:
2026-03-01
Conditions
Peripheral Arterial Disease
Interventions
DRUG
No Results Yet
60
Participants
Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-07-16
Completion:
2025-10-03
Conditions
Parkinson Disease
Interventions
BIOLOGICAL
OTHER
No Results Yet
40000
Participants
Stroke Thrombectomy and Aneurysm Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-17
Completion:
2055-01-01
Conditions
Stroke
Thromboses, Intracranial
Aneurysm, Brain
Interventions
PROCEDURE
No Results Yet
207
Participants
BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-13
Completion:
2028-09-01
Conditions
Primary Hyperoxaluria Type 1
No Results Yet
600
Participants
External Pop Out cs vs Conventional Method for Fetal Head Extraction in Repeatedcaesarean Section.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-16
Completion:
2022-07-24
Conditions
EPO Teqnique in Fetal Head Extraction
Interventions
PROCEDURE
No Results Yet
431
Participants
Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-12-20
Completion:
2021-12-16
Conditions
Post-Intensive Care Syndrome
Anxiety
Depression
Stress Disorders, Post-Traumatic
Quality of Life
Satisfaction, Patient
Interventions
BEHAVIORAL
No Results Yet
55
Participants
Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-11-15
Completion:
2025-12-17
Conditions
Febrile Neutropenia
Interventions
DRUG
No Results Yet
60
Participants
Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-02
Completion:
2026-12-31
Conditions
Malocclusion
Obstructive Sleep Apnea
No Results Yet
22
Participants
Involvement of Skeletal Muscle Fibrocytes in sarcOpenia in Patients With Chronic ObstRuctive Pulmonary Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-29
Completion:
2025-11-21
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
PROCEDURE
No Results Yet
40
Participants
Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-08-01
Completion:
2022-03-01
Conditions
COVID-19 Acute Respiratory Distress Syndrome
Sedation Complication
ICU Acquired Weakness
Interventions
DRUG
No Results Yet
240
Participants
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-01-24
Completion:
2026-02-28
Conditions
Peripheral Vascular Diseases
Interventions
BEHAVIORAL
No Results Yet
300
Participants
Diabetic Nephropathy in People With Diabetes. Prevalence and Predictive Factors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-08-10
Completion:
2043-12-31
Conditions
Chronic Kidney Diseases
Albuminuria
Diabetic Kidney Disease
Diabetic Nephropathies
Diabetes type2
Molecular Sequence Variation
Kidney Biopsy
Interventions
PROCEDURE
No Results Yet
28
Participants
Study to Evaluate Combined Treatment of Daratumumab, Bortezomib and Dexamethasone in PBL Patients.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-07-11
Completion:
2026-01-01
Conditions
Plasmablastic Lymphoma
Interventions
DRUG
No Results Yet
400
Participants
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-08-04
Completion:
2028-11-30
Conditions
Solid Tumor, Adult
Non-small Cell Lung Cancer
Melanoma
Interventions
DRUG
No Results Yet
126
Participants
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-07-26
Completion:
2029-12-10
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
400
Participants
A Trial of Pharmacist Management of Oral Anticoagulation THerapy Versus Enhanced Usual CARe in the communitY for AF
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-03-13
Completion:
2025-08-31
Conditions
Atrial Fibrillation
Stroke
Interventions
DRUG
No Results Yet
74
Participants
A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of mRNA-3705 in Participants With Isolated Methylmalonic Acidemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-08-06
Completion:
2028-07-01
Conditions
Methylmalonic Acidemia
Interventions
BIOLOGICAL
No Results Yet
40
Participants
Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-15
Completion:
2026-04-30
Conditions
Pain
Opioid Use
Androgen Deficiency
Back Pain
Interventions
DRUG
No Results Yet
1314
Participants
Studying the Modification of Attention Bias Remotely After Trauma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-04-20
Completion:
2025-06-30
Conditions
Post Traumatic Stress Disorder
Interventions
DEVICE
No Results Yet
282
Participants
A Multi-Phase Study Examining Hospital to Home Transitions for Children With Medical Complexity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-07-23
Completion:
2027-03-31
Conditions
Children With Medical Complexity (CMC)
Interventions
BEHAVIORAL
No Results Yet
18
Participants
Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-14
Completion:
2027-01-31
Conditions
Gastroesophageal Junction (GEJ) Cancers
Advanced HNSCC
Interventions
DRUG
BIOLOGICAL
No Results Yet
45
Participants
Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-08-18
Completion:
2025-01-15
Conditions
Diffuse Large B-cell Lymphoma
Interventions
GENETIC
No Results Yet
150
Participants
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-05-26
Completion:
2030-12-31
Conditions
Ulcerative Colitis
Ulcerative Colitis Chronic
Inflammatory Bowel Diseases
Crohn's Disease
Interventions
DRUG
No Results Yet
28
Participants
Study Evaluating 111In-Panitumumab for Nodal Staging in Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-30
Completion:
2027-03-31
Conditions
Head and Neck Cancer
Interventions
DRUG
PROCEDURE
No Results Yet
363
Participants
Antibody Persistence And Long Term Safety Of A Chikungunya Virus Vaccine (VLA1553)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-04-02
Completion:
2025-12-31
Conditions
Chikungunya Virus Infection
Interventions
BIOLOGICAL
No Results Yet
1000
Participants
A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-07
Completion:
2026-06-19
Conditions
Lymphoma
Interventions
OTHER
No Results Yet
43
Participants
Protonix Treatment of Maintenance of Healing in Pediatric Participants Aged 1-11 Years and 12-17 Years
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-01-13
Completion:
2025-12-16
Conditions
Esophagitis
Interventions
DRUG
No Results Yet
293
Participants
Determining the Effectiveness of Working Out Dads to Reduce Mental Health Difficulties in Fathers of Young Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-24
Completion:
2024-05-31
Conditions
Mental Health Issue
Interventions
BEHAVIORAL
No Results Yet
101
Participants
Emotions in Multiple Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-23
Completion:
2025-02-25
Conditions
Multiple Sclerosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
23
Participants
VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-04-18
Completion:
2027-01-31
Conditions
Solid Tumor
Rhabdomyosarcoma
Interventions
DRUG
No Results Yet
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