Clinical Trials Updated in 2025

NCT06780969 | COMPLETED | NA

100 Participants

A Sustainable Choice to Reduce Carbon Footprint

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-01-31

Completion: 2025-08-06

Conditions

Breastfeeding

Interventions

BEHAVIORAL

No Results Yet

NCT06780111 | RECRUITING | PHASE1/PHASE2

228 Participants

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-07-30

Completion: 2032-01-04

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06777784 | COMPLETED | NA

40 Participants

Modern Nicotine Oral Product Abuse Liability

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-02-03

Completion: 2025-03-05

Conditions

Smoking Tobacco Use

Interventions

OTHER

No Results Yet

NCT06777368 | RECRUITING

225 Participants

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2025-02-06

Completion: 2029-03-31

Conditions

Aortic Stenosis

Interventions

DEVICE

No Results Yet

NCT06776783 | RECRUITING | PHASE3

520 Participants

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-09-24

Completion: 2027-05-31

Conditions

Respiratory Distress Syndrome Pre-term Infants

Interventions

COMBINATION_PRODUCT OTHER

No Results Yet

NCT06771648 | COMPLETED | NA

41 Participants

Daxxin Psoriasis Shampoo PMCF

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-02-24

Completion: 2025-12-19

Conditions

Scalp Psoriasis

Interventions

DEVICE

No Results Yet

NCT06770374 | RECRUITING | NA

400 Participants

Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-02-01

Completion: 2026-07-31

Conditions

Vascular Access Complication Skin and Subcutaneous Tissue Disorders Phlebitis Pain

Interventions

PROCEDURE DEVICE OTHER

No Results Yet

NCT06762392 | RECRUITING | NA

40 Participants

Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-01-01

Completion: 2025-12-30

Conditions

Anterior Cruciate Ligament Reconstruction Rehabilitation

Interventions

OTHER

No Results Yet

NCT06761976 | AVAILABLE

Expanded Access to Provide Sevabertinib (BAY 2927088) for the Treatment of Locally Advanced or Metastatic NSCLC With HER2 Mutation

Study Type: EXPANDED_ACCESS

Last Updated: 2025-12-23

Conditions

Advanced Non-small Cell Lung Cancer Cancer

Interventions

DRUG

No Results Yet

NCT06756308 | RECRUITING | PHASE2

25 Participants

A Study of Enasidenib in People With T-Cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-24

Completion: 2027-12-31

Conditions

T-cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06754176 | RECRUITING | NA

100 Participants

Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-04-17

Completion: 2026-12-31

Conditions

Atrial Fibrillation (AF) Atrial Fibrillation (Paroxysmal)

Interventions

BEHAVIORAL

No Results Yet

NCT06747455 | RECRUITING | PHASE3

438 Participants

BCG for Therapeutic Use Phase Ⅲ Clinical Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-04-08

Completion: 2028-10-01

Conditions

BCG

Interventions

DRUG

No Results Yet

NCT06740708 | RECRUITING | NA

2070 Participants

Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-04-28

Completion: 2026-11-30

Conditions

Hypertension Type 2 Diabetes Mellitus (T2DM) Tobacco Smoking

Interventions

BEHAVIORAL

No Results Yet

NCT06739811 | RECRUITING | NA

40 Participants

Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-21

Completion: 2026-06-30

Conditions

Type I Diabetes

Interventions

DEVICE

No Results Yet

NCT06735989 | COMPLETED | NA

86 Participants

Moral Reasoning Intervention on Moral Justification Abilities

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2022-11-18

Completion: 2024-02-19

Conditions

Moral Development Moral Dilemma Healthy Controls Moral Justification

Interventions

OTHER

No Results Yet

NCT06734364 | RECRUITING | NA

96 Participants

Buddy Tape vs. Splint for Metacarpal Shaft Fracture Recovery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-11-05

Completion: 2027-02-05

Conditions

Non-thumb Metacarpal Shaft Fracture

Interventions

DEVICE

No Results Yet

NCT06728410 | RECRUITING | PHASE2

38 Participants

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2026-01-31

Completion: 2026-07-31

Conditions

Intrahepatic Cholangiocarcinoma FGFR2 Gene Rearrangement FGFR2 Gene Mutation

Interventions

DRUG

No Results Yet

NCT06725420 | COMPLETED | NA

63 Participants

Ultrasound-Guided Injection vs Intramuscular Steroid for Carpal Tunnel Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-03-15

Completion: 2025-09-19

Conditions

Carpal Tunnel Syndrome (CTS) Chronic Pain

Interventions

OTHER DEVICE

No Results Yet

NCT06725368 | RECRUITING | PHASE2

46 Participants

Carboplatin + Paclitaxel + Cetuximab (PCC) After Failure of Pembrolizumab +/- First-line Chemotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-01-24

Completion: 2028-01-31

Conditions

Head and Neck Cancer

Interventions

DRUG

No Results Yet

NCT06723249 | COMPLETED | NA

45 Participants

Stingless Bee Honey Augmentation in Major Depressive Disorders

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-15

Completion: 2025-08-10

Conditions

Major Depressive Disorder (MDD)

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06717698 | RECRUITING | PHASE2

465 Participants

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-02

Completion: 2026-09-01

Conditions

Chronic Kidney Disease

Interventions

DRUG

No Results Yet

NCT06712680 | RECRUITING | PHASE1/PHASE2

115 Participants

A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-27

Completion: 2028-04-10

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06712290 | WITHDRAWN | NA

0 Participants

Connective Tissue Matrix Compared to Steroid Injections for Rotator Cuff Tendinopathy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-25

Completion: 2025-12-17

Conditions

Rotator Cuff Tendinopathy

Interventions

DRUG

No Results Yet

NCT06703398 | RECRUITING | PHASE2

98 Participants

A Study of GC101 TIL in Advanced Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-20

Completion: 2026-07-10

Conditions

Melanoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06700447 | ACTIVE_NOT_RECRUITING | NA

2163 Participants

Protecting Against HIV Vaccine Misinformation With Adolescent Girls and Young Women in South Africa

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-07-24

Completion: 2026-12-31

Conditions

Misinformation HIV Vaccine

Interventions

BEHAVIORAL

No Results Yet

NCT06690775 | RECRUITING | PHASE2

230 Participants

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-20

Completion: 2027-10-31

Conditions

Epithelial Ovarian Cancer Primary Peritoneal Fallopian Tube Cancer Endometrioid Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT06688370 | TERMINATED

12 Participants

The Performance and Safety of Petit Drill in the French Paediatric Population: a Post-market Clinical Follow-up Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-03-14

Completion: 2024-11-07

Conditions

Sore-throat Cough

Interventions

DEVICE

Results Available

NCT06687980 | RECRUITING | PHASE3

136 Participants

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-25

Completion: 2027-04-12

Conditions

Lichen Simplex Chronicus

Interventions

DRUG

No Results Yet

NCT06687967 | RECRUITING | PHASE3

136 Participants

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 1)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-28

Completion: 2027-04-12

Conditions

Lichen Simplex Chronicus

Interventions

DRUG

No Results Yet

NCT06684964 | RECRUITING

40 Participants

RWE,NIS,Prospective Study for the Effectiveness, Tolerability and Adherence of Asciminib in Saudi Arabia. (ASC4REAL)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-24

Completion: 2026-12-30

Conditions

Chronic Myelogenous Leukemia in Chronic Phase

Interventions

OTHER

No Results Yet

NCT06680557 | COMPLETED | NA

49 Participants

Exercises on Children and Adolescents With Type 1 Diabetes Mellitus (T1DM)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-01-01

Completion: 2025-08-31

Conditions

Diabetes Mellitus, Type 1

Interventions

BEHAVIORAL

No Results Yet

NCT06680128 | RECRUITING | PHASE1/PHASE2

402 Participants

A Study to Assess the Safety, Reactogenicity, and Immunogenicity of SK Japanese Encephalitis Messenger Ribonucleic Acid (mRNA) Vaccines (GBP560) in Healthy Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-02-24

Completion: 2026-06-26

Conditions

Japanese Encephalitis Virus Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06675812 | ACTIVE_NOT_RECRUITING | NA

200 Participants

Improving Help-seeking Propensity Through a Micro-intervention Targeting Common Concerns Among Individuals With Alcohol Problems: A Randomized Controlled Experiment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-18

Completion: 2025-12-02

Conditions

Alcohol Abuse Harmful Alcohol Use Hazardous Alcohol Use Hazardous Drinking Risky Drinking

Interventions

OTHER

No Results Yet

NCT06671496 | RECRUITING | PHASE3

600 Participants

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-10

Completion: 2027-05-18

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT06670040 | RECRUITING | NA

24 Participants

Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-16

Completion: 2026-03-31

Conditions

ASD Autism Spectrum Disorder Autism Depression - Major Depressive Disorder MDD

Interventions

PROCEDURE

No Results Yet

NCT06660394 | RECRUITING | PHASE3

160 Participants

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-25

Completion: 2026-08-21

Conditions

Dravet Syndrome

Interventions

DRUG

No Results Yet

NCT06660121 | RECRUITING

30 Participants

Electrochemotherapy for Desmoid Tumors

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-10-17

Completion: 2028-08-01

Conditions

Desmoid Fibromatosis

Interventions

PROCEDURE

No Results Yet

NCT06656715 | RECRUITING

100 Participants

Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-16

Completion: 2026-09-01

Conditions

Heart Failure

No Results Yet

NCT06655246 | RECRUITING | PHASE1

157 Participants

A Study of Ziftomenib, an Oral Menin Inhibitor, in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-27

Completion: 2027-12-31

Conditions

Gastrointestinal Stromal Tumor (GIST) Gastrointestinal Stromal Tumor (GIST) of the Gastrointestinal Tract Gastrointestinal Stromal Cancer Gastrointestinal Stromal Neoplasm Gastrointestinal Stromal Tumor, Malignant Gastrointestinal Stromal Cell Tumors

Interventions

DRUG

No Results Yet

NCT06640985 | ACTIVE_NOT_RECRUITING | NA

43 Participants

EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-04

Completion: 2026-02-28

Conditions

Wound Healing Diabetic Foot Foot Ulcer, Diabetic Venous Ulcer

Interventions

DEVICE

No Results Yet