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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06846099 | COMPLETED | PHASE1
69 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-12-07
Completion: 2025-05-30
Conditions
Ovarian Cancer Cervical Cancer Endometrial Cancer Breast Cancer Solid Tumor Cancer
Interventions
DRUG
No Results Yet
NCT06840210 | NOT_YET_RECRUITING
200000 Participants

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2026-02-01
Completion: 2028-12-01
Conditions
Acute Kidney Injury
No Results Yet
NCT06838676 | RECRUITING | PHASE2
60 Participants

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-10
Completion: 2028-07-31
Conditions
Diffuse Intrinsic Pontine Gliomas (DIPG) Progressive DIPG Refractory DIPG Recurrent DIPG H3K27-altered High Grade Glioma
Interventions
DRUG
No Results Yet
NCT06835491 | RECRUITING | PHASE3
674 Participants

Prophylactic Anti-aRrhythmic Therapy With Amiodarone in Critically Ill Patients Admitted for an Out-of-hospital Cardiac Arrest With Initial Shockable Rhythm

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-06
Completion: 2027-01-15
Conditions
Ventricular Arrhythmias and Cardiac Arrest
Interventions
DRUG
No Results Yet
NCT06834191 | RECRUITING
80 Participants

Relationship Between Immunosuppressive Treatment Status and Clinical Course of Parkinson's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-01
Completion: 2027-12-31
Conditions
Parkinson Disease
No Results Yet
NCT06828328 | RECRUITING | EARLY_PHASE1
10 Participants

A Study of GC203 TIL in PDCA (RJ)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-02-10
Completion: 2028-01-31
Conditions
Pancreatic Cancer Pancratic Ductal Adenocarcinoma Treatment Side Effects Tumor Infiltrating Lymphocytes
Interventions
BIOLOGICAL
No Results Yet
NCT06824064 | RECRUITING | PHASE2
150 Participants

Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-17
Completion: 2027-12-31
Conditions
Metastatic Colorectal Cancer Advanced Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06822491 | ACTIVE_NOT_RECRUITING
28 Participants

Early Magnetic Resonance Imaging Response of the Dominant Intraprostatic Lesion After Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer and Correlation With Prostate Specific Antigen Response

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-20
Completion: 2026-06-30
Conditions
Prostate Carcinoma Localized Prostate Adenocarcinoma Stereotactic Body Radiotherapy Stereotactic Radiotherapy Magnetic Resonance Imaging Multiparametric MRI
No Results Yet
NCT06818136 | RECRUITING
600 Participants

Bladder EpiCheck European Haematuria Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-20
Completion: 2026-02-28
Conditions
Hematuria Cystoscopy Urothelial Carcinoma Bladder Urothelial Carcinoma of the Renal Pelvis and Ureter Urothelial Carcinoma of the Urinary Bladder
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06812494 | RECRUITING | PHASE2
200 Participants

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-07
Completion: 2027-01-15
Conditions
HIV
Interventions
BIOLOGICAL
No Results Yet
NCT06806033 | RECRUITING | PHASE2
100 Participants

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-05
Completion: 2027-01-31
Conditions
B-Cell Non-Hodgkins Lymphoma
Interventions
DRUG
No Results Yet
NCT06799624 | NOT_YET_RECRUITING
100 Participants

Prognostic Role of molEcular classiFication in Fertility-sparing treAtment of Endometrial canCEr

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2026-01-01
Completion: 2028-01-31
Conditions
Uterine Cancer
Interventions
OTHER
No Results Yet
NCT06797193 | RECRUITING | NA
60 Participants

Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-13
Completion: 2027-03-31
Conditions
Portal Hypertension
Interventions
OTHER PROCEDURE DRUG
No Results Yet
NCT06789406 | RECRUITING | NA
55 Participants

PMCF Study of the Axonics SNM System Model 5101 (R20)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-18
Completion: 2027-01-31
Conditions
Urinary Urge Incontinence (UUI) Urinary Frequency (UF) Overactive Bladder (OAB)
Interventions
DEVICE
No Results Yet
NCT06786130 | RECRUITING
100 Participants

Societal Burden Associated With Type 1 Diabetes in Canada

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-09
Completion: 2025-12-31
Conditions
Type 1 Diabetes Mellitus Quality of Life (QOL) Work Productivity Caregiver Subjective Burden
Interventions
OTHER
No Results Yet
NCT06786013 | COMPLETED
80 Participants

Effects of Interscalene Block on Visual Clarity in Arthroscopic Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-17
Completion: 2025-04-01
Conditions
Rotator Cuff Syndrome
No Results Yet
NCT06783621 | ACTIVE_NOT_RECRUITING | PHASE4
130 Participants

A Study to Evaluate Patient Satisfaction With the Overall Face and Neck Appearance After Combined Treatment of OnabotulinumtoxinA, JUVÉDERM® Products, KYBELLA, CoolSculpting Elite and SkinMedica Products

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-16
Completion: 2026-03-31
Conditions
Facial Contouring
Interventions
DRUG DEVICE OTHER
No Results Yet
NCT06783088 | COMPLETED
20 Participants

Quantification With Lutetium-177 on Cadmium-Zinc-Telluride Camera 3D

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-10
Completion: 2025-04-10
Conditions
Prostate Cancer
No Results Yet
NCT06780995 | RECRUITING | NA
60 Participants

Power Exercise for Stroke Recovery: The POWER Pilot Trial (POWER-P)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-15
Completion: 2027-02-28
Conditions
Stroke
Interventions
OTHER
No Results Yet
NCT06780969 | COMPLETED | NA
100 Participants

A Sustainable Choice to Reduce Carbon Footprint

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-31
Completion: 2025-08-06
Conditions
Breastfeeding
Interventions
BEHAVIORAL
No Results Yet
NCT06780111 | RECRUITING | PHASE1/PHASE2
228 Participants

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-30
Completion: 2032-01-04
Conditions
Esophageal Squamous Cell Carcinoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06777784 | COMPLETED | NA
40 Participants

Modern Nicotine Oral Product Abuse Liability

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-02-03
Completion: 2025-03-05
Conditions
Smoking Tobacco Use
Interventions
OTHER
No Results Yet
NCT06777368 | RECRUITING
225 Participants

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-02-06
Completion: 2029-03-31
Conditions
Aortic Stenosis
Interventions
DEVICE
No Results Yet
NCT06776783 | RECRUITING | PHASE3
520 Participants

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-24
Completion: 2027-05-31
Conditions
Respiratory Distress Syndrome Pre-term Infants
Interventions
COMBINATION_PRODUCT OTHER
No Results Yet
NCT06771648 | COMPLETED | NA
41 Participants

Daxxin Psoriasis Shampoo PMCF

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-02-24
Completion: 2025-12-19
Conditions
Scalp Psoriasis
Interventions
DEVICE
No Results Yet
NCT06770374 | RECRUITING | NA
400 Participants

Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-02-01
Completion: 2026-07-31
Conditions
Vascular Access Complication Skin and Subcutaneous Tissue Disorders Phlebitis Pain
Interventions
PROCEDURE DEVICE OTHER
No Results Yet
NCT06762392 | RECRUITING | NA
40 Participants

Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-01
Completion: 2025-12-30
Conditions
Anterior Cruciate Ligament Reconstruction Rehabilitation
Interventions
OTHER
No Results Yet
NCT06761976 | AVAILABLE

Expanded Access to Provide Sevabertinib (BAY 2927088) for the Treatment of Locally Advanced or Metastatic NSCLC With HER2 Mutation

Study Type: EXPANDED_ACCESS
Last Updated: 2025-12-23
Conditions
Advanced Non-small Cell Lung Cancer Cancer
Interventions
DRUG
No Results Yet
NCT06756308 | RECRUITING | PHASE2
25 Participants

A Study of Enasidenib in People With T-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-24
Completion: 2027-12-31
Conditions
T-cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06754176 | RECRUITING | NA
100 Participants

Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-17
Completion: 2026-12-31
Conditions
Atrial Fibrillation (AF) Atrial Fibrillation (Paroxysmal)
Interventions
BEHAVIORAL
No Results Yet
NCT06747455 | RECRUITING | PHASE3
438 Participants

BCG for Therapeutic Use Phase â…¢ Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-08
Completion: 2028-10-01
Conditions
BCG
Interventions
DRUG
No Results Yet
NCT06740708 | RECRUITING | NA
2070 Participants

Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-28
Completion: 2026-11-30
Conditions
Hypertension Type 2 Diabetes Mellitus (T2DM) Tobacco Smoking
Interventions
BEHAVIORAL
No Results Yet
NCT06739811 | RECRUITING | NA
40 Participants

Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-21
Completion: 2026-06-30
Conditions
Type I Diabetes
Interventions
DEVICE
No Results Yet
NCT06735989 | COMPLETED | NA
86 Participants

Moral Reasoning Intervention on Moral Justification Abilities

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-11-18
Completion: 2024-02-19
Conditions
Moral Development Moral Dilemma Healthy Controls Moral Justification
Interventions
OTHER
No Results Yet
NCT06734364 | RECRUITING | NA
96 Participants

Buddy Tape vs. Splint for Metacarpal Shaft Fracture Recovery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-05
Completion: 2027-02-05
Conditions
Non-thumb Metacarpal Shaft Fracture
Interventions
DEVICE
No Results Yet
NCT06731907 | RECRUITING | PHASE2
90 Participants

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-30
Completion: 2032-03-12
Conditions
Non-small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06728410 | RECRUITING | PHASE2
38 Participants

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-01-31
Completion: 2026-07-31
Conditions
Intrahepatic Cholangiocarcinoma FGFR2 Gene Rearrangement FGFR2 Gene Mutation
Interventions
DRUG
No Results Yet
NCT06725420 | COMPLETED | NA
63 Participants

Ultrasound-Guided Injection vs Intramuscular Steroid for Carpal Tunnel Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-15
Completion: 2025-09-19
Conditions
Carpal Tunnel Syndrome (CTS) Chronic Pain
Interventions
OTHER DEVICE
No Results Yet
NCT06725368 | RECRUITING | PHASE2
46 Participants

Carboplatin + Paclitaxel + Cetuximab (PCC) After Failure of Pembrolizumab +/- First-line Chemotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-24
Completion: 2028-01-31
Conditions
Head and Neck Cancer
Interventions
DRUG
No Results Yet
NCT06723249 | COMPLETED | NA
45 Participants

Stingless Bee Honey Augmentation in Major Depressive Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-15
Completion: 2025-08-10
Conditions
Major Depressive Disorder (MDD)
Interventions
DIETARY_SUPPLEMENT
No Results Yet
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