Clinical Trials

Showing trials with last updates posted in 2025.

NCT06577766 | ACTIVE_NOT_RECRUITING | PHASE1
88 Participants

A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-03
Completion: 2026-03-23
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06576921 | RECRUITING | PHASE2
116 Participants

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-15
Completion: 2026-03-01
Conditions
Stomach Neoplasms Immune Checkpoint Inhibitors
Interventions
DRUG
No Results Yet
NCT06564818 | RECRUITING | PHASE3
220 Participants

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-17
Completion: 2026-08-31
Conditions
Major Depressive Disorder
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT06560736 | RECRUITING | NA
30 Participants

Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-01
Completion: 2026-08-31
Conditions
Phenylketonurias
Interventions
BEHAVIORAL
No Results Yet
NCT06557785 | ACTIVE_NOT_RECRUITING | PHASE1
53 Participants

A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-25
Completion: 2026-01-03
Conditions
HIV Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06554795 | RECRUITING | PHASE1/PHASE2
360 Participants

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-03
Completion: 2027-02-28
Conditions
Solid Tumor, Adult
Interventions
DRUG
No Results Yet
NCT06548542 | RECRUITING | PHASE2
500 Participants

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-04
Completion: 2027-12-31
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06545942 | RECRUITING | PHASE1
220 Participants

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-13
Completion: 2027-05-31
Conditions
Advanced Solid Tumor Metastatic Solid Tumor Prostate Cancer Pancreas Cancer Breast Cancer Ovarian Cancer Homologous Recombination Deficiency
Interventions
DRUG
No Results Yet
NCT06512051 | RECRUITING | PHASE1/PHASE2
248 Participants

A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-07-30
Completion: 2026-10-31
Conditions
Advanced or Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06505928 | ACTIVE_NOT_RECRUITING | PHASE2
90 Participants

A Clinical Trial of Hepalatide for Injection in Patients With Chronic Hepatitis D

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-11
Completion: 2026-05-31
Conditions
Hepatitis D
Interventions
DRUG
No Results Yet
NCT06504654 | RECRUITING
60 Participants

Interoception and Eating Behaviors in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-31
Completion: 2026-03-31
Conditions
Obesity, Childhood Eating Behavior
No Results Yet
NCT06503159 | TERMINATED | NA
14 Participants

Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-07
Completion: 2025-09-11
Conditions
Vaping Teens Healthy Volunteers
Interventions
BEHAVIORAL
No Results Yet
NCT06486987 | ACTIVE_NOT_RECRUITING | NA
10 Participants

CHAMP T 2 Pilot of CIMT by Tele-Video

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hemiplegic Cerebral Palsy
Interventions
OTHER
No Results Yet
NCT06483854 | RECRUITING | NA
230907 Participants

Healer-initiated HIV Counseling and Testing Versus Standard of Care in Rural South Africa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-25
Completion: 2028-05-01
Conditions
Hiv
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06483334 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
38 Participants

A Study of Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-07-17
Completion: 2028-03-31
Conditions
Metastatic Urothelial Carcinoma Locally Advanced Urothelial Carcinoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06477302 | RECRUITING
281 Participants

Scale of Therapeutic Adherence to Respiratory Rahabilitation for Lung Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-23
Completion: 2026-06-23
Conditions
Lung Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06477120 | RECRUITING | NA
60 Participants

Time-restricted Eating Among Pregnant Females With Severe Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-09
Completion: 2026-08-31
Conditions
Obesity, Morbid Time Restricted Eating Pregnancy Weight Gain
Interventions
BEHAVIORAL
No Results Yet
NCT06474546 | RECRUITING | NA
54 Participants

Feasibility of a Diet Intervention for Juvenile Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-07
Completion: 2028-08-31
Conditions
Arthritis, Juvenile Arthritis, Childhood Juvenile Idiopathic Arthritis
Interventions
OTHER
No Results Yet
NCT06473831 | ACTIVE_NOT_RECRUITING | NA
25 Participants

MagDI Australia Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-13
Completion: 2025-09-04
Conditions
Obesity Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT06469723 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Protocol for Inpatient Nursing Frailty Assessment (INFA)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-03
Completion: 2025-12-31
Conditions
Functional Status Frailty
Interventions
OTHER
No Results Yet
NCT06468228 | RECRUITING | PHASE3
1280 Participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06467955 | RECRUITING | NA
60 Participants

MagDI Canada Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-10
Completion: 2026-02-28
Conditions
Obesity Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT06459973 | RECRUITING | PHASE1/PHASE2
252 Participants

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-04
Completion: 2027-07-31
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06449001 | RECRUITING | PHASE3
6 Participants

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-08-11
Completion: 2027-05-28
Conditions
Paroxysmal Nocturnal Hemoglobinuria PNH Extravascular Hemolysis
Interventions
DRUG
No Results Yet
NCT06445972 | RECRUITING | PHASE1/PHASE2
210 Participants

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-07
Completion: 2026-12-28
Conditions
Gastroesophageal Junction Gastroesophageal Adenocarcinoma Esophageal Neoplasms Esophageal Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06430229 | COMPLETED | NA
110 Participants

Atelectasis Frequency in Different Ventilation Modes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-20
Completion: 2024-06-10
Conditions
Lung Ultrasound General Anesthesia Pulmonary Atelectasis Mechanical Ventilation Complication
Interventions
PROCEDURE
No Results Yet
NCT06424340 | RECRUITING | PHASE1/PHASE2
29 Participants

MB-dNPM1-TCR.1 in Relapsed/Refractory AML

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-01
Completion: 2028-06-30
Conditions
Leukemia, Myeloid, Acute
Interventions
BIOLOGICAL
No Results Yet
NCT06424327 | RECRUITING
600 Participants

A Registry for People With Lung Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-15
Completion: 2029-05-15
Conditions
Lung Cancer Lung Cancer Stage I
Interventions
OTHER
No Results Yet
NCT06422689 | ACTIVE_NOT_RECRUITING | PHASE4
1507 Participants

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-10
Completion: 2026-04-29
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06415916 | RECRUITING
100 Participants

Ultrasound and Clinical Approach for the Dynamic Assessment of Fluid Tolerance in the Intensive Care Unit

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-15
Completion: 2026-03-31
Conditions
Volume Expander
Interventions
PROCEDURE
No Results Yet
NCT06400849 | RECRUITING | NA
60 Participants

Comparison of the Efficacy of Cryotherapy Combined With Compression in Preventing Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-04-04
Completion: 2026-12-04
Conditions
Non-metastatic Breast Cancer
Interventions
DEVICE
No Results Yet
NCT06397989 | RECRUITING | NA
5500 Participants

Peanut-based School Meals in Rural Ghana to Improve Attendance and Retention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-07
Completion: 2026-11-30
Conditions
School Attendance School Dropouts School Enrollment School Feeding Programs Child Nutrition
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06393946 | ACTIVE_NOT_RECRUITING
150 Participants

Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-10-20
Completion: 2026-04-28
Conditions
Chronic Rhinosinusitis With Nasal Polyposis
Interventions
DRUG
No Results Yet
NCT06392490 | COMPLETED | NA
48 Participants

The Effectiveness of Peer-education Programs for Adolescents Diagnosed With Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-14
Completion: 2025-08-12
Conditions
Asthma Adolescent Behavior Self Efficacy Peer Support and Chronic Disease
Interventions
OTHER
No Results Yet
NCT06392477 | RECRUITING | PHASE1
96 Participants

A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Relapsed/ Refractory B-Cell Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-07-08
Completion: 2028-01-21
Conditions
B-cell Non Hodgkin Lymphoma
Interventions
DRUG
No Results Yet
NCT06389136 | RECRUITING | PHASE3
200 Participants

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-12
Completion: 2026-08-31
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06386978 | COMPLETED | NA
90 Participants

Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-30
Completion: 2025-09-30
Conditions
Obstetric
Interventions
PROCEDURE
No Results Yet
NCT06383572 | RECRUITING | PHASE1/PHASE2
44 Participants

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-26
Completion: 2027-04-01
Conditions
Lymphodepleting Chemotherapy Myeloid Malignancies
Interventions
DRUG
No Results Yet
NCT06383390 | RECRUITING | PHASE3
10000 Participants

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-04-30
Completion: 2029-02-28
Conditions
Atherosclerotic Cardiovascular Disease (ASCVD) Chronic Kidney Disease (CKD)
Interventions
DRUG
No Results Yet
NCT06380309 | RECRUITING | EARLY_PHASE1
89 Participants

A Clinical Study on Evaluating Intravenous Administration of IDOV-SAFE

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-06
Completion: 2025-12-30
Conditions
Advanced Malignant Solid Tumor of Digestive System
Interventions
BIOLOGICAL
No Results Yet
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