Clinical Trials

Showing trials with last updates posted in 2025.

NCT04418830 | ENROLLING_BY_INVITATION
1050 Participants

Lumbar Interbody Implant Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2020-10-01
Completion: 2025-12-31
Conditions
Degenerative Disc Disease Degenerative Spondylolisthesis Degenerative Scoliosis Spinal Stenosis Sagittal Deformity
No Results Yet
NCT04418817 | COMPLETED
36 Participants

Modulus in XLIF Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2020-03-22
Completion: 2024-01-31
Conditions
Degenerative Scoliosis Degenerative Disc Disease Degenerative Spondylolisthesis
No Results Yet
NCT04384770 | ACTIVE_NOT_RECRUITING
179 Participants

CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer, MIRAGE Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2020-05-12
Completion: 2026-04-01
Conditions
Prostate Adenocarcinoma
Interventions
RADIATION OTHER
No Results Yet
NCT04358939 | COMPLETED | NA
405 Participants

Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-04-27
Completion: 2021-02-21
Conditions
Acute Respiratory Distress Syndrome COVID-19
Interventions
OTHER
No Results Yet
NCT04354311 | COMPLETED | NA
60 Participants

Prediction of Hemodynamic Response to Intubation by ANI Variation During Standardized Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2014-02-02
Completion: 2014-12-31
Conditions
Tracheal Intubation Morbidity Pain
Interventions
DEVICE
No Results Yet
NCT04341623 | ACTIVE_NOT_RECRUITING | NA
35 Participants

Xerosis and Use of Topical Moisturizer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-01-21
Completion: 2026-03-31
Conditions
Xerosis Due to Atopic Dermatitis
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT04333745 | ACTIVE_NOT_RECRUITING | NA
22 Participants

Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-09-01
Completion: 2026-03-01
Conditions
Kidney Stone
Interventions
OTHER DIETARY_SUPPLEMENT
No Results Yet
NCT04322318 | RECRUITING | PHASE2
256 Participants

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-10-19
Completion: 2027-07-01
Conditions
Anaplastic Kidney Wilms Tumor Recurrent Kidney Wilms Tumor Stage II Kidney Wilms Tumor Stage III Kidney Wilms Tumor Stage IV Kidney Wilms Tumor
Interventions
PROCEDURE DRUG RADIATION
No Results Yet
NCT04309474 | COMPLETED | PHASE2
121 Participants

A Safety and Efficacy Study of Intravenous (IV) Elezanumab Assessing Change in Neurologic Function in Adult Participants With Acute Ischemic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-11-09
Completion: 2024-04-18
Conditions
Acute Ischemic Stroke
Interventions
DRUG
NCT04293562 | RECRUITING | PHASE3
1186 Participants

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-07-21
Completion: 2029-06-30
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT04284267 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-03-01
Completion: 2025-10-30
Conditions
Bipolar Disorder
Interventions
DEVICE
No Results Yet
NCT04261712 | ACTIVE_NOT_RECRUITING | PHASE2
43 Participants

A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-01-29
Completion: 2028-03-31
Conditions
Acromegaly
Interventions
DRUG
No Results Yet
NCT04248439 | ACTIVE_NOT_RECRUITING | PHASE2
5 Participants

Gene Therapy for Fanconi Anemia, Complementation Group A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-07-15
Completion: 2026-05-05
Conditions
Fanconi Anemia Complementation Group A
Interventions
BIOLOGICAL
No Results Yet
NCT04234646 | ACTIVE_NOT_RECRUITING | NA
600 Participants

Patient Navigation 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-12-09
Completion: 2026-05-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT04234568 | ACTIVE_NOT_RECRUITING | PHASE1
31 Participants

Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-07-20
Completion: 2024-09-17
Conditions
Metastatic Digestive System Neuroendocrine Neoplasm Metastatic Neuroendocrine Tumor
Interventions
PROCEDURE DRUG
NCT04227054 | ACTIVE_NOT_RECRUITING | NA
15 Participants

Abdominal Aortic Aneurysm Sac Healing and Prevention of Endoleaks

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-09-09
Completion: 2023-08-30
Conditions
Abdominal Aortic Aneurysm
Interventions
DEVICE
No Results Yet
NCT04200898 | COMPLETED | NA
286 Participants

Clinical Investigation of the Cheetah System For The Correction of Myopia With and Without Astigmatism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-12-31
Completion: 2024-12-06
Conditions
Myopia Astigmatism
Interventions
DEVICE
No Results Yet
NCT04182204 | COMPLETED | PHASE3
270 Participants
NCT04175613 | COMPLETED | PHASE3
160 Participants

A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-12-20
Completion: 2025-10-30
Conditions
Psoriasis
Interventions
DRUG
No Results Yet
NCT04174352 | RECRUITING | EARLY_PHASE1
12 Participants

FES Imaging to Optimize Tamoxifen for Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-10-20
Completion: 2026-12-31
Conditions
ERα+ Breast Cancer ESR1 Gene Mutation
Interventions
DRUG DIAGNOSTIC_TEST
No Results Yet
NCT04164199 | ENROLLING_BY_INVITATION | PHASE3
430 Participants

Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-12-19
Completion: 2026-12-31
Conditions
Advanced Malignancies
Interventions
DRUG
No Results Yet
NCT04128709 | RECRUITING | NA
50 Participants

Measurement of Bladder Pressure With a Novel External Device (Cystomanometer) - Home Use

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-11-19
Completion: 2026-12-31
Conditions
Urinary Bladder, Neurogenic
Interventions
DEVICE
No Results Yet
NCT04125836 | COMPLETED | PHASE3
135 Participants

A Trial to Assess the Long-term Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-10-10
Completion: 2025-04-24
Conditions
Acromegaly
Interventions
DRUG
No Results Yet
NCT04116411 | ACTIVE_NOT_RECRUITING | PHASE2
220 Participants

A Clinical Trial Evaluating the Efficacy of Valganciclovir in Glioblastoma Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-09-04
Completion: 2027-09-16
Conditions
Glioblastoma Multiforme
Interventions
DRUG RADIATION
No Results Yet
NCT04109079 | RECRUITING | NA
1900 Participants

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-02-26
Completion: 2030-02-28
Conditions
Breast Cancer Sentinel Lymph Node Neoplasm, Breast
Interventions
PROCEDURE RADIATION
No Results Yet
NCT04094688 | ACTIVE_NOT_RECRUITING | PHASE3
455 Participants

Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-10-29
Completion: 2024-07-15
Conditions
Colorectal Adenocarcinoma
Interventions
DRUG DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT04074005 | COMPLETED
188 Participants

Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2020-03-01
Completion: 2024-01-31
Conditions
Cesarean Section Epidural; Anesthesia
No Results Yet
NCT04033445 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
1064 Participants

A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-09-26
Completion: 2023-09-19
Conditions
Ulcerative Colitis
Interventions
DRUG
NCT03997123 | ACTIVE_NOT_RECRUITING | PHASE3
923 Participants

Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-06-25
Completion: 2026-03-16
Conditions
Triple Negative Breast Neoplasms
Interventions
DRUG
No Results Yet
NCT03988062 | COMPLETED | NA
13 Participants

Aneurysm Packing With the Expandable TrelliX Coil System - A Prospective Safety Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2018-11-21
Completion: 2021-05-31
Conditions
Ruptured or Unruptured Cerebral Aneurysms
Interventions
DEVICE
No Results Yet
NCT03973606 | COMPLETED | NA
306 Participants

Assessment of the Health Literacy Among Arab Women in East Jerusalem

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-07-30
Completion: 2023-09-30
Conditions
Health Literacy Cardiovascular Diseases
Interventions
OTHER
No Results Yet
NCT03969043 | COMPLETED | NA
60 Participants

Brain Correlates of Visual Processing of Emotional Scenes in ACTion and EMOtional Judgments During Normal VIeillissement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-05-10
Completion: 2021-12-03
Conditions
Aging
Interventions
OTHER
No Results Yet
NCT03959085 | RECRUITING | PHASE3
4997 Participants

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-10-31
Completion: 2030-03-31
Conditions
B Acute Lymphoblastic Leukemia B Lymphoblastic Lymphoma Central Nervous System Leukemia Mixed Phenotype Acute Leukemia Testicular Leukemia
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
No Results Yet
NCT03955640 | TERMINATED | PHASE1
3 Participants

Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-05-20
Completion: 2021-08-26
Conditions
Metastatic Malignant Neoplasm in the Chest Wall Recurrent Breast Carcinoma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT03955627 | COMPLETED | NA
12 Participants

REJOIN Trial for Older Breast Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-06-15
Completion: 2025-07-29
Conditions
Breast Cancer Female
Interventions
BEHAVIORAL
No Results Yet
NCT03953300 | ACTIVE_NOT_RECRUITING | PHASE4
75 Participants

Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-10-08
Completion: 2026-09-09
Conditions
Asthma
Interventions
BIOLOGICAL
No Results Yet
NCT03948971 | RECRUITING | NA
10 Participants

Prospective Measurement of Normal Venous Sinus Pressures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2020-01-13
Completion: 2026-05-31
Conditions
Intracranial Venous Pressures
Interventions
PROCEDURE
No Results Yet
NCT03938363 | COMPLETED | NA
40 Participants

Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2019-10-23
Completion: 2022-06-13
Conditions
Blepharospasm Cervical Dystonia, Primary
Interventions
OTHER DRUG DIAGNOSTIC_TEST
No Results Yet
NCT03924531 | COMPLETED | NA
36 Participants

Promoting Adherence to Anti-Hypertensive Medications and Lifestyle Guidelines Through Mindfulness Practice

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-08-01
Completion: 2019-03-31
Conditions
Health Behavior Modification Using Mindfulness
Interventions
BEHAVIORAL
No Results Yet
NCT03901963 | ACTIVE_NOT_RECRUITING | PHASE3
200 Participants
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