Clinical Trials

Showing trials with last updates posted in 2025.

NCT03089827 | ENROLLING_BY_INVITATION
800 Participants

Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2014-05-21
Completion: 2030-04-30
Conditions
Alzheimer Disease Mild Cognitive Impairment
No Results Yet
NCT03071406 | ACTIVE_NOT_RECRUITING | PHASE2
50 Participants

Randomized Study of Nivolumab+Ipilimumab+/- SBRT for Metastatic Merkel Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-03-14
Completion: 2022-04-06
Conditions
Merkel Cell Carcinoma Skin Cancer
Interventions
DRUG RADIATION
NCT03067181 | RECRUITING | PHASE3
1780 Participants

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-05-25
Completion: 2027-06-30
Conditions
Childhood Extracranial Germ Cell Tumor Extragonadal Embryonal Carcinoma Germ Cell Tumor Malignant Germ Cell Tumor Malignant Ovarian Teratoma Stage I Ovarian Choriocarcinoma Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7 Stage I Testicular Choriocarcinoma AJCC v6 and v7 Stage I Testicular Embryonal Carcinoma AJCC v6 and v7 Stage I Testicular Seminoma AJCC v6 and v7 Stage I Testicular Yolk Sac Tumor AJCC v6 and v7 Stage II Ovarian Choriocarcinoma Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7 Stage II Testicular Choriocarcinoma AJCC v6 and v7 Stage II Testicular Embryonal Carcinoma AJCC v6 and v7 Stage II Testicular Yolk Sac Tumor AJCC v6 and v7 Stage III Ovarian Choriocarcinoma Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7 Stage III Testicular Choriocarcinoma AJCC v6 and v7 Stage III Testicular Embryonal Carcinoma AJCC v6 and v7 Stage III Testicular Yolk Sac Tumor AJCC v6 and v7 Stage IV Ovarian Choriocarcinoma Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7 Testicular Mixed Choriocarcinoma and Embryonal Carcinoma Testicular Mixed Choriocarcinoma and Teratoma Testicular Mixed Choriocarcinoma and Yolk Sac Tumor
Interventions
OTHER PROCEDURE BIOLOGICAL DRUG
No Results Yet
NCT03027479 | COMPLETED | NA
70 Participants

Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-03-01
Completion: 2019-07-16
Conditions
Weight Loss Ovarian Carcinoma Endometrial Carcinoma
Interventions
OTHER
No Results Yet
NCT02985957 | COMPLETED | PHASE2
351 Participants

A Study of Nivolumab Plus Ipilimumab, Ipilimumab Alone, or Cabazitaxel in Men With Metastatic Castration-Resistant Prostate Cancer (CheckMate 650)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-03-26
Completion: 2022-04-05
Conditions
Prostate Cancer
Interventions
BIOLOGICAL DRUG
NCT02981628 | RECRUITING | PHASE2
80 Participants

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-06-19
Completion: 2026-12-31
Conditions
Recurrent B Acute Lymphoblastic Leukemia Recurrent B Lymphoblastic Lymphoma Refractory B Acute Lymphoblastic Leukemia Refractory B Lymphoblastic Lymphoma
Interventions
DRUG PROCEDURE BIOLOGICAL
No Results Yet
NCT02909673 | COMPLETED | NA
3028 Participants

School Based Program to Prevent Teen Dating Violence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2018-01-18
Completion: 2021-10-03
Conditions
Violence
Interventions
BEHAVIORAL
NCT02907060 | COMPLETED | PHASE3
1224 Participants

Mechanical cervicAl ripeninG for Women With PrOlongedPregnancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-01-27
Completion: 2018-12-12
Conditions
Prolonged Pregnancy
Interventions
DEVICE DRUG
No Results Yet
NCT02905071 | COMPLETED | NA
226 Participants

Validation of a Scale of Well-being at Work

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2013-11-30
Completion: 2017-11-26
Conditions
Adjustment Disorder
Interventions
OTHER
No Results Yet
NCT02893267 | COMPLETED | NA
96 Participants

Multimodal Treatment for Hemiplegic Shoulder Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-01-31
Completion: 2024-09-30
Conditions
Shoulder Pain Stroke
Interventions
DEVICE OTHER
NCT02891395 | COMPLETED | PHASE2
65 Participants

Efficacy and Safety of Nilotinib in Patients With a Chronic Disease of the Graft Against the Host

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2012-12-24
Completion: 2017-07-26
Conditions
Graft Versus Host Disease
Interventions
DRUG
No Results Yet
NCT02870517 | ACTIVE_NOT_RECRUITING | NA
212 Participants

Pre-operative Stress Reduction With Music

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-01-31
Completion: 2026-12-31
Conditions
Pediatric Pre-operative Stress
Interventions
OTHER
No Results Yet
NCT02854436 | COMPLETED | PHASE2
289 Participants

An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-08-31
Completion: 2021-01-26
Conditions
Prostatic Neoplasms
Interventions
DRUG
NCT02844101 | COMPLETED | NA
80 Participants

Assess Whether Knowledge by the Younger of the Function of the Accelerometer Determines Its Amount of Physical Activity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2013-07-31
Completion: 2015-06-30
Conditions
Physical Activity
Interventions
DEVICE
No Results Yet
NCT02829918 | COMPLETED | PHASE2
54 Participants

Study of Nivolumab in Patients With Advanced Refractory Biliary Tract Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-10-05
Completion: 2019-03-27
Conditions
Biliary Tract Cancer Biliary Tract Neoplasms
Interventions
DRUG
NCT02821169 | COMPLETED | PHASE3
184 Participants

Infiltration in the Region of the Palatine Ganglion Spheno by Ropivacaine on Postoperative Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-04-30
Completion: 2019-06-30
Conditions
Pain
Interventions
DRUG
No Results Yet
NCT02812979 | COMPLETED | NA
25 Participants

Evaluation of the Effectiveness of the Nebulization Bronchodilators Under High Nasal Flow Humidified

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-06-30
Completion: 2018-04-27
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DEVICE
No Results Yet
NCT02803268 | COMPLETED | PHASE1
24 Participants

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of MT-8554 in Female Subjects Experiencing Vasomotor Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-06-30
Completion: 2017-01-31
Conditions
Vasomotor Symptoms
Interventions
DRUG
No Results Yet
NCT02779855 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
50 Participants

Talimogene Laherparepvec in Combination With Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-05-02
Completion: 2020-09-20
Conditions
Breast Cancer Ductal Carcinoma Invasive Breast Carcinoma Invasive Ductal Breast Carcinoma
Interventions
BIOLOGICAL DRUG
NCT02724579 | ACTIVE_NOT_RECRUITING | PHASE2
45 Participants

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-11-17
Completion: 2027-06-30
Conditions
Medulloblastoma
Interventions
DRUG OTHER PROCEDURE RADIATION
No Results Yet
NCT02681328 | ACTIVE_NOT_RECRUITING
328 Participants

Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2016-05-01
Completion: 2026-12-01
Conditions
Thyroid
Interventions
OTHER
No Results Yet
NCT02675647 | COMPLETED | PHASE4
60 Participants

Heparin Based on Ideal Body Weight for Cardiopulmonary Bypass in Obese Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-12-31
Completion: 2016-12-31
Conditions
Cardiac Surgery Cardiopulmonary Bypass Obese Patients (BMI ≥ 30 kg/m²)
Interventions
DRUG PROCEDURE
No Results Yet
NCT02675309 | COMPLETED | PHASE1
28 Participants

A Study to Investigate the Effect of MT-8554 on the Pharmacokinetics of Simvastatin and Rosuvastatin in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-02-29
Completion: 2016-03-31
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT02670226 | COMPLETED | NA
37 Participants

Muscular Biomarkers in Amyotrophic Lateral Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-03-29
Completion: 2019-10-15
Conditions
Amyotrophic Lateral Sclerosis
Interventions
OTHER
No Results Yet
NCT02638090 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
120 Participants

Pembro and Vorinostat for Patients With Stage IV Non-small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-03-22
Completion: 2024-01-21
Conditions
Lung Cancer Non-small Cell Lung Cancer
Interventions
DRUG
NCT02621775 | COMPLETED | NA
120 Participants

Effectiveness of Two Stress Management Programs in Adaptation Disorder With Anxiety (ADA)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-09-14
Completion: 2018-06-16
Conditions
Adjustment Disorders Psychological Stress
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT02606695 | COMPLETED
306 Participants

Comprehensive Spinal Alignment Planning Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2016-03-31
Completion: 2020-12-31
Conditions
Spine Surgery
Interventions
DEVICE
No Results Yet
NCT02573974 | COMPLETED | NA
51 Participants

Skeletal Muscle Energy Metabolism in Undernourished Patients With Gastrointestinal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2016-01-19
Completion: 2018-12-04
Conditions
Undernutrition Gastrointestinal Cancer
Interventions
OTHER
No Results Yet
NCT02563444 | COMPLETED | NA
25 Participants

Interest in Using Ultrasound Fusion in Percutaneous Interventional Radiology

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2014-06-30
Completion: 2015-05-31
Conditions
Tissular Lesion
Interventions
DEVICE
No Results Yet
NCT02549495 | COMPLETED
168 Participants

Impact of Community Health Workers on Adherence to Therapy for Non-Communicable Chronic Disease in Chiapas, Mexico

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2013-03-31
Completion: 2018-04-30
Conditions
Hypertension Diabetes Mellitus, Type 2
NCT02536209 | COMPLETED | PHASE1
20 Participants

A Study to Investigate the Pharmacodynamic Effect of Single Doses of MT-8554 in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-08-31
Completion: 2015-11-30
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT02517489 | COMPLETED | PHASE3
952 Participants

Community-Acquired Pneumonia : Evaluation of Corticosteroids

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-10-28
Completion: 2020-07-19
Conditions
Community Acquired Pneumonia
Interventions
DRUG
No Results Yet
NCT02509468 | COMPLETED | PHASE2
63 Participants

suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-09-30
Completion: 2019-03-31
Conditions
Vascular Malformation
Interventions
DRUG
No Results Yet
NCT02489318 | ACTIVE_NOT_RECRUITING | PHASE3
1052 Participants

A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-11-27
Completion: 2020-09-07
Conditions
Prostate Cancer
Interventions
DRUG
NCT02478528 | COMPLETED | NA
18 Participants

Study of Effects of Light on the Vigilance and Cognitive Performance Following a Night Without Sleep

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-05-31
Completion: 2015-06-30
Conditions
Healthy Volunteers
Interventions
DEVICE OTHER
No Results Yet
NCT02457988 | TERMINATED | EARLY_PHASE1
120 Participants

The Cirrhosis Outpatient Optimization, Readmission & Safety Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-04-30
Completion: 2017-10-31
Conditions
Cirrhosis
Interventions
DEVICE
No Results Yet
NCT02429102 | COMPLETED | PHASE1
135 Participants

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-04-30
Completion: 2015-11-30
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT02408276 | COMPLETED
130 Participants

Longitudinal Evaluation of Hip Cartilage Degeneration: FAI

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2014-12-31
Completion: 2025-12-18
Conditions
Femoroacetabular Impingement
Interventions
OTHER
No Results Yet
NCT02402244 | RECRUITING
75000 Participants

Project: Every Child for Younger Patients With Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2015-11-03
Completion: 2030-12-31
Conditions
Adrenal Gland Pheochromocytoma Carcinoma In Situ Central Nervous System Neoplasm Childhood Immature Teratoma Childhood Kidney Neoplasm Childhood Langerhans Cell Histiocytosis Childhood Mature Teratoma Congenital Mesoblastic Nephroma Desmoid Fibromatosis Ganglioneuroma Lymphoproliferative Disorder Malignant Neoplasm Malignant Solid Neoplasm Melanocytic Neoplasm Myeloproliferative Neoplasm Neoplasm of Uncertain Malignant Potential Neuroendocrine Neoplasm Stromal Neoplasm
Interventions
OTHER
No Results Yet
NCT02378493 | COMPLETED | NA
33 Participants

Evaluation of the Antibiofilmogramme® Test During Diabetic Foot Infections

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2015-12-16
Completion: 2019-07-17
Conditions
Diabetic Foot Staphylococcus Aureus
Interventions
BIOLOGICAL
No Results Yet
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