Clinical Trials
Showing trials with last updates posted in 2025.
15
Participants
A Study of Modakafusp Alfa Together With Daratumumab Adults With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-01-23
Completion:
2024-05-22
Conditions
Multiple Myeloma
Interventions
DRUG
28
Participants
A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-10-31
Completion:
2025-10-16
Conditions
Hepatic Impairment
Interventions
DRUG
No Results Yet
2904
Participants
Safety of Ibuprofen After Major Orthopaedic Surgeries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-17
Completion:
2025-08-19
Conditions
Safety Issues
Analgesia
Analgesic Adverse Reaction
Postoperative Pain
Postoperative Complications
Knee Arthropathy
Pain, Acute
Hip Arthropathy
Interventions
DRUG
No Results Yet
60
Participants
Effect of Acute Bout of Exercise on Levels of PAHSA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-05-01
Completion:
2025-12-12
Conditions
Insulin Sensitivity
Interventions
OTHER
No Results Yet
614
Participants
A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-03-29
Completion:
2026-02-13
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
11
Participants
A Trial That Evaluates Disease Characteristics in Hemophilia B Adult Male Participants Receiving Prophylaxis With Standard of Care Factor IX Protein (FIX) Replacement Therapy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-01-17
Completion:
2026-01-21
Conditions
Hemophilia B
Interventions
OTHER
No Results Yet
17
Participants
A Study to Assess the Efficacy and Safety of Apremilast in Japanese Pediatric Participants With Moderate to Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-01-25
Completion:
2025-11-20
Conditions
Plaque Psoriasis
Interventions
DRUG
No Results Yet
700
Participants
Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-10-24
Completion:
2027-10-31
Conditions
Miscarriage
Early Pregnancy Loss
No Results Yet
15
Participants
A Study of Modakafusp Alfa in Adult Participants With Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-01-12
Completion:
2024-06-04
Conditions
Multiple Myeloma
Interventions
DRUG
1590
Participants
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-10-25
Completion:
2031-04-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
148
Participants
Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-01-01
Completion:
2026-06-30
Conditions
Osteoarthritis, Knee
Interventions
BIOLOGICAL
OTHER
No Results Yet
69
Participants
Study to Assess SLN124 in Patients With Polycythemia Vera
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-01-26
Completion:
2026-09-30
Conditions
Polycythemia Vera
Interventions
DRUG
No Results Yet
520
Participants
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-11-11
Completion:
2027-08-17
Conditions
Carcinoma, Non-small-Cell Lung
Interventions
DRUG
No Results Yet
10800
Participants
Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-10-19
Completion:
2026-06-01
Conditions
E-cigarette Use
Interventions
BEHAVIORAL
No Results Yet
708
Participants
DIStal Versus COnventional Radial Access for COMPLEX Large-bore Percutaneous Coronary Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-31
Completion:
2026-06-01
Conditions
Vascular Access Site Occlusion
Interventions
PROCEDURE
No Results Yet
57
Participants
A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-12-13
Completion:
2026-06-09
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
30
Participants
Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-09-30
Completion:
2026-06-30
Conditions
Stroke
Interventions
DEVICE
No Results Yet
100
Participants
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-06-01
Completion:
2026-12-31
Conditions
Chronic Pain
Interventions
DRUG
No Results Yet
92
Participants
A Care Empowerment Program Using Virtual Reality for Family Caregivers of People With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-01
Completion:
2023-07-01
Conditions
Dementia Family Caregiver
Interventions
OTHER
No Results Yet
24
Participants
Furmonertinib in EGFR-Mutant NSCLC With Brain Metastases (iFORCE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-11
Completion:
2025-12-12
Conditions
Furmonertinib
EGFR-mutation
NSCLC
Brain Metastases
Interventions
DRUG
No Results Yet
43
Participants
Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-29
Completion:
2024-10-22
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
DRUG
30
Participants
Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-03-27
Completion:
2026-03-01
Conditions
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Interventions
DRUG
BIOLOGICAL
PROCEDURE
No Results Yet
500
Participants
A Study of Daratumumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-12-15
Completion:
2026-01-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
120
Participants
PTSD Treatment for Incarcerated Men and Women: WPP
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-01-04
Completion:
2026-01-31
Conditions
PTSD
Interventions
BEHAVIORAL
No Results Yet
17
Participants
TOLER-ENT Study: A Study to Investigate the Tolerance of the High Energy, High Protein Formula Sondalis® HP 2 kcal
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-08
Completion:
2024-05-28
Conditions
Malnutrition
Interventions
DIETARY_SUPPLEMENT
No Results Yet
24
Participants
A Study in Healthy People to Compare 2 Different Formulations of BI 1015550 Taken With or Without Food
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-15
Completion:
2022-09-30
Conditions
Healthy
Interventions
DRUG
450
Participants
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-11
Completion:
2028-01-30
Conditions
Candidemia
Candidiasis, Invasive
Interventions
DRUG
No Results Yet
191
Participants
Targeting Inflammation for Endometrial Cancer Prevention
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-12-01
Completion:
2026-12-31
Conditions
Endometrial Carcinoma
Interventions
PROCEDURE
OTHER
No Results Yet
418
Participants
A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-05
Completion:
2024-01-03
Conditions
Advanced or Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
225
Participants
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-29
Completion:
2027-04-27
Conditions
Advanced or Metastatic Colorectal Cancer
Interventions
BIOLOGICAL
No Results Yet
48
Participants
Effects of Motor Imagery and Action Observation in People With Multiple Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-06-01
Completion:
2024-04-01
Conditions
Multiple Sclerosis
Interventions
OTHER
No Results Yet
398
Participants
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-06-07
Completion:
2026-11-30
Conditions
Gastric Adenocarcinoma
Gastroesophageal Junction (GEJ) Adenocarcinoma
Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
40
Participants
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-05-12
Completion:
2026-01-31
Conditions
Sickle Cell Anemia
Beta Thalassemia
Interventions
RADIATION
DRUG
BIOLOGICAL
No Results Yet
25
Participants
R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-23
Completion:
2030-11-30
Conditions
Lymphadenopathy Retroperitoneal
Stage II Testicular Seminoma
Interventions
PROCEDURE
No Results Yet
399
Participants
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-10
Completion:
2024-08-05
Conditions
SGA, Turner Syndrome, Noonan Syndrome, ISS
Interventions
DRUG
No Results Yet
201
Participants
Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-09-23
Completion:
2027-05-14
Conditions
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions
DRUG
No Results Yet
262
Participants
Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-04-11
Completion:
2028-03-30
Conditions
Urinary Bladder Neoplasms
Receptors, Fibroblast Growth Factor
Interventions
DRUG
No Results Yet
40
Participants
An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-11-13
Completion:
2026-06-30
Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG
No Results Yet
55
Participants
Feasibility of a Train-the-Trainer Delivered Exercise Intervention in Firefighters
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-01
Completion:
2025-09-26
Conditions
Firefighter
High Intensity Interval Training
Interventions
BEHAVIORAL
No Results Yet
158
Participants
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-22
Completion:
2027-08-31
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
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