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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07039292 | RECRUITING | NA
208 Participants

Clinical Alternatives for Reducing Harm Using E-cigarettes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-25
Completion: 2029-05-31
Conditions
Smoking E-Cig Use Oncology
Interventions
BEHAVIORAL
No Results Yet
NCT07038889 | NOT_YET_RECRUITING | NA
60 Participants

Overground Virtual Reality (VR) Gait Rehabilitation for Traumatic Brain Injury (TBI)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2027-06-30
Conditions
Traumatic Brain Injury Stroke Gait Training
Interventions
DEVICE
No Results Yet
NCT07038837 | RECRUITING | PHASE4
70000 Participants

Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-16
Completion: 2026-12-31
Conditions
Malaria Infection Malaria Vaccines
Interventions
OTHER
No Results Yet
NCT07038733 | RECRUITING | NA
10 Participants

Investigation of Lymph Node Biology in Kidney Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2027-12-31
Conditions
Renal Cell Carcinoma (RCC)
Interventions
PROCEDURE
No Results Yet
NCT07038356 | RECRUITING | PHASE3
536 Participants

Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-08
Completion: 2026-04-30
Conditions
Acute Decompensated Heart Failure (ADHF)
Interventions
DRUG
No Results Yet
NCT07037901 | RECRUITING | PHASE2
220 Participants

A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-17
Completion: 2026-11-30
Conditions
Atopic Dermatitis Atopic Dermatitis Eczema Eczema
Interventions
DRUG
No Results Yet
NCT07034547 | RECRUITING | NA
30 Participants

Effect of Botulinum Toxin Type A on Motor Function in Children With Cerebral Palsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-11
Completion: 2026-01-31
Conditions
Cerebral Palsy (CP) Spasticity Due to Cerebral Palsy Hemiparesis
Interventions
PROCEDURE
No Results Yet
NCT07029412 | RECRUITING | PHASE2
10 Participants

Study to Evaluate Efficacy and Dose Response of Imapextide (STEADI)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-26
Completion: 2025-12-22
Conditions
Postbariatric Hypoglycemia
Interventions
DRUG
No Results Yet
NCT07029269 | RECRUITING | PHASE3
454 Participants

Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-16
Completion: 2028-06-01
Conditions
Gastric Adenocarcinoma Laparoscopic Gastrectomy Complications
Interventions
PROCEDURE
No Results Yet
NCT07029009 | RECRUITING | PHASE2
50 Participants

Liraglutide Treatment in Patients With Maturity-onset Diabetes of the Young (MODY)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-08
Completion: 2026-08-31
Conditions
Maturity Onset Diabetes of the Young
Interventions
DRUG
No Results Yet
NCT07026591 | RECRUITING
40 Participants

Epilepsy and Driving

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-06
Completion: 2027-11-30
Conditions
Epilepsy
No Results Yet
NCT07017946 | NOT_YET_RECRUITING | PHASE1/PHASE2
20 Participants

Intestinal Microbiome Transplant in ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-15
Completion: 2026-11-01
Conditions
Amyotrophic Lateral Sclerosis ALS
Interventions
DRUG
No Results Yet
NCT07016698 | RECRUITING | NA
600 Participants

Real-World Registry of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-29
Completion: 2029-03-31
Conditions
Peripheral Arterial Disease(PAD)
Interventions
DEVICE
No Results Yet
NCT07014618 | RECRUITING
420 Participants

Navigator-Assisted Hypofractionation (NAVAH) on Radiation Therapy Completion in Breast Cancer and Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-16
Completion: 2029-10-31
Conditions
Breast Cancer Prostate Cancer
Interventions
OTHER
No Results Yet
NCT07011940 | NOT_YET_RECRUITING | NA
300 Participants

Walk With Me (WWM) for Perinatal Grief

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2027-08-01
Conditions
Grief Post Traumatic Stress Disorder Suicidal Ideation Miscarriage Stillbirth Infant Death
Interventions
BEHAVIORAL
No Results Yet
NCT07010133 | NOT_YET_RECRUITING | NA
60 Participants

Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2026-12-31
Conditions
Depression Physical Inactivity
Interventions
BEHAVIORAL
No Results Yet
NCT07008300 | WITHDRAWN | EARLY_PHASE1
0 Participants

Safety, Tolerability, and Pharmacokinetics of an Oral Withania Somnifera Product in Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-07-01
Completion: 2025-12-01
Conditions
Healthy Aging
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07006831 | RECRUITING
400 Participants

A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-14
Completion: 2026-12-31
Conditions
Kidney Disease Kidney Transplant Transplant Recipient Renal Function Cell-free DNA NGS
No Results Yet
NCT07002073 | RECRUITING | NA
102 Participants

Comparison of the Hemodynamic Effects of Ketamine - Dexmedetomidine (Ketodex) Versus Propofol-ketamine Admixture (Ketofol) During Induction of Anesthesia in Elderly: A Randomized Comparative Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-01
Completion: 2025-12-31
Conditions
Ketamine-dexmedetomidine Induction of Anesthesia
Interventions
DRUG
No Results Yet
NCT07000734 | RECRUITING | PHASE2
20 Participants

Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-07-28
Completion: 2026-05-31
Conditions
Aging Cognitive Decline Older Adults Cardiovascular Sedentary Behaviors Immune Senescence Motor Function
Interventions
BEHAVIORAL DRUG DIETARY_SUPPLEMENT
No Results Yet
NCT07000552 | COMPLETED | NA
68 Participants

Emotional Freedom Technique During Pregnancy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-15
Completion: 2025-10-15
Conditions
Fear of Birth Birth Memory Postpartum Sense of Security
Interventions
OTHER
No Results Yet
NCT07000357 | RECRUITING | PHASE3
15100 Participants

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-04
Completion: 2029-10-26
Conditions
Cardiovascular Disease
Interventions
DRUG
No Results Yet
NCT06993792 | RECRUITING | PHASE3
1200 Participants

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-15
Completion: 2027-01-31
Conditions
Obesity Overweight Type 2 Diabetes
Interventions
DRUG
No Results Yet
NCT06992440 | ENROLLING_BY_INVITATION | PHASE2
78 Participants

Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-26
Completion: 2030-07-31
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
No Results Yet
NCT06987695 | ACTIVE_NOT_RECRUITING | PHASE3
279 Participants

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-13
Completion: 2027-04-27
Conditions
Obesity Disease
Interventions
DRUG
No Results Yet
NCT06984627 | RECRUITING | PHASE2
30 Participants

A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-02
Completion: 2026-08-25
Conditions
Graves' Disease
Interventions
DRUG
No Results Yet
NCT06981247 | NOT_YET_RECRUITING | NA
84 Participants

Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2026-06-30
Conditions
Physical Activity Life Style Dietary Habits Cardiovascular Diseases
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06977308 | NOT_YET_RECRUITING | PHASE1
115 Participants

A Multimodal Imaging Study of Dopamine in Early Psychosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-03-01
Completion: 2029-10-01
Conditions
Clinical High Risk for Psychosis (CHR)
Interventions
DRUG
No Results Yet
NCT06973291 | ACTIVE_NOT_RECRUITING | PHASE3
606 Participants

A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-07-09
Completion: 2026-06-05
Conditions
Plaque Psoriasis
Interventions
DRUG
No Results Yet
NCT06970847 | RECRUITING | PHASE3
220 Participants

64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-16
Completion: 2026-12-31
Conditions
Prostate Cancer Prostate Cancer Patients With Detectable PSA Following Prostatectomy Prostate Cancer Recurrent Prostate Cancer Patients Who Have Brachytherapy Seed Implant Prostate Cancer Patients Treated by Radiotherapy Cryotherapy
Interventions
DRUG
No Results Yet
NCT06968143 | RECRUITING | NA
150 Participants

Investigating Patient Satisfaction With Smart Knee Implants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-01
Completion: 2027-04-30
Conditions
Total Knee Arthroplasty Knee Replacement Knee Replacement Arthroplasty Knee Osteoarthritis
Interventions
DEVICE
No Results Yet
NCT06960577 | RECRUITING | PHASE3
150 Participants

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-15
Completion: 2028-10-31
Conditions
Urinary Bladder Neoplasms Immune Checkpoint Inhibitors Methotrexate Vinblastine Doxorubicin Cisplatin Gemcitabine
Interventions
DRUG
No Results Yet
NCT06955013 | RECRUITING
118 Participants

Ultrasound to View Abdominal Wall Muscle Layers

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-25
Completion: 2027-12-31
Conditions
Healthy Volunteers
No Results Yet
NCT06952803 | RECRUITING | PHASE3
700 Participants

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-06
Completion: 2033-03-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06951698 | RECRUITING | PHASE3
274 Participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-11
Completion: 2026-11-01
Conditions
Bipolar-I Disorder With Mania or Mania With Mixed Features
Interventions
DRUG OTHER
No Results Yet
NCT06947135 | RECRUITING | NA
166 Participants

Stellate Ganglion Morphine Infiltration on Myocardial Ischemia-Reperfusion Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-29
Completion: 2026-06-04
Conditions
Acute Myocardial Infarction
Interventions
DRUG
No Results Yet
NCT06943755 | RECRUITING | PHASE2/PHASE3
440 Participants

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-07-21
Completion: 2029-06-30
Conditions
Pancreatic Neuroendocrine Tumor (pNET) Extra-Pancreatic Neuroendocrine Tumor (epNET)
Interventions
DRUG
No Results Yet
NCT06941844 | RECRUITING | PHASE3
140 Participants

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-04-14
Completion: 2026-11-30
Conditions
Major Depressive Disorder
Interventions
OTHER DRUG
No Results Yet
NCT06940830 | RECRUITING | PHASE4
250 Participants

Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatment With Efanesoctocog Alfa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-21
Completion: 2028-12-31
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
NCT06939751 | RECRUITING
250 Participants

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-28
Completion: 2031-01-01
Conditions
Cardiac Failure Graft Rejection
No Results Yet
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