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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06152705 | RECRUITING | NA
210 Participants

Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-16
Completion: 2027-10-01
Conditions
Depression Depressive Disorder, Major Depressive Episode
Interventions
DEVICE
No Results Yet
NCT06143774 | RECRUITING | PHASE1
30 Participants

Study of TRX-920 for Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-31
Completion: 2026-03-30
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06141720 | RECRUITING | NA
20 Participants

Feasibility of a Mindfulness Intervention for Endometriosis Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-30
Completion: 2026-06-30
Conditions
Endometriosis Pain Mindfulness
Interventions
BEHAVIORAL
No Results Yet
NCT06139328 | TERMINATED | PHASE2
160 Participants

IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-05
Completion: 2025-09-02
Conditions
Myocardial Infarction
Interventions
DRUG
No Results Yet
NCT06138184 | NOT_YET_RECRUITING | NA
68 Participants

Learning Theory Patient Education for Anticoagulants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-04-30
Completion: 2026-10-31
Conditions
Knowledge, Attitudes, Practice
Interventions
BEHAVIORAL
No Results Yet
NCT06137781 | COMPLETED | NA
35 Participants

Digital Prehabilitation for Patients Undergoing Major Elective Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-02-19
Completion: 2024-09-17
Conditions
Surgery
Interventions
BEHAVIORAL
Results Available
NCT06132113 | RECRUITING | PHASE1
55 Participants

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-22
Completion: 2027-02-09
Conditions
Neuroendocrine Neoplasms
Interventions
DRUG
No Results Yet
NCT06130553 | RECRUITING | PHASE1/PHASE2
234 Participants

A Study of AZD3470, a PRMT5 Inhibitor, in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-18
Completion: 2026-02-26
Conditions
Advanced Solid Tumors That Are MTAP Deficient
Interventions
DRUG
No Results Yet
NCT06130280 | RECRUITING | PHASE2
32 Participants

A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-08
Completion: 2026-11-30
Conditions
Colorectal Cancer Liver Metastases
Interventions
RADIATION
No Results Yet
NCT06127199 | RECRUITING | NA
656 Participants

Contraceptive Efficacy Study of Ovaprene

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-19
Completion: 2026-06-30
Conditions
Contraception
Interventions
DEVICE
No Results Yet
NCT06125977 | ACTIVE_NOT_RECRUITING
73 Participants

Impact of Non-Exudative Type 1 MNV on AMD Progression

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-01-30
Completion: 2027-08-31
Conditions
Age-Related Macular Degeneration Neovascularization, Choroidal
No Results Yet
NCT06121505 | RECRUITING | PHASE2
114 Participants

Phase II Trial: Low-Dose Radiation + SBRT + Sintilimab + Chemotherapy vs. Sintilimab + Chemotherapy in Locally Advanced or Metastatic Squamous Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-03-01
Completion: 2027-02-28
Conditions
Lung Squamous Cell Carcinoma
Interventions
RADIATION DRUG
No Results Yet
NCT06121323 | COMPLETED | NA
12 Participants

Physiological Effects of Lactate in Individuals With Chronic Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-22
Completion: 2025-01-16
Conditions
Heart Failure, Systolic
Interventions
OTHER
No Results Yet
NCT06118255 | ACTIVE_NOT_RECRUITING | PHASE3
25 Participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-21
Completion: 2026-09-03
Conditions
Dravet Syndrome
Interventions
DRUG
No Results Yet
NCT06112379 | ACTIVE_NOT_RECRUITING | PHASE3
1902 Participants

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-14
Completion: 2028-11-20
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT06110793 | RECRUITING | PHASE1/PHASE2
49 Participants

A Study of Lenvatinib, Pembrolizumab, and Fulvestrant in People With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-29
Completion: 2026-11-30
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT06109285 | ACTIVE_NOT_RECRUITING | NA
16 Participants

Validation of i-ROP DL to Detect More Than Mild ROP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-06-25
Completion: 2026-02-01
Conditions
Retinopathy of Prematurity ROP
Interventions
DEVICE
No Results Yet
NCT06108609 | COMPLETED
100 Participants

Validation of the French Version of the Hearing Aid Benefit Measurement COSI and IOI-HA Questionnaires

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-05-16
Completion: 2024-08-08
Conditions
Hearing Impairment
Interventions
OTHER
No Results Yet
NCT06107725 | TERMINATED | PHASE2/PHASE3
2 Participants

Maimonides Minocycline in Stroke Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-01
Completion: 2024-05-09
Conditions
Stroke, Acute Ischemic Stroke Hemorrhagic Stroke Mortality Morbidity
Interventions
DRUG
Results Available
NCT06102057 | RECRUITING | PHASE2
110 Participants

PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-07-01
Completion: 2026-06-30
Conditions
Stage III Non-small Cell Lung Cancer Locally Advanced Unresectable
Interventions
RADIATION DRUG
No Results Yet
NCT06098508 | COMPLETED | NA
3 Participants

Osteopathic Manual Treatment for Hemiplegic Shoulder Pain and Upper Extremity Function in Stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-07-23
Completion: 2025-11-10
Conditions
Hemiplegic Shoulder Pain Osteopathic Manipulative Treatment
Interventions
OTHER
No Results Yet
NCT06094634 | ACTIVE_NOT_RECRUITING | NA
562 Participants

IGHID 12219 - A Brief Alcohol Intervention for PrEP Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-03
Completion: 2027-01-31
Conditions
Unhealthy Alcohol Use
Interventions
BEHAVIORAL
No Results Yet
NCT06093425 | NOT_YET_RECRUITING | PHASE3
820 Participants

Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-06-30
Completion: 2029-10-01
Conditions
Gastric Cancer Gastroesophageal-junction Cancer Advanced Cancer
Interventions
DRUG
No Results Yet
NCT06075953 | RECRUITING | PHASE2
400 Participants

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-02-17
Completion: 2028-11-30
Conditions
Ductal Carcinoma in Situ
Interventions
DRUG
No Results Yet
NCT06072378 | RECRUITING | NA
50 Participants

The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-31
Completion: 2028-09-01
Conditions
Memory, Short-Term
Interventions
BEHAVIORAL
No Results Yet
NCT06071221 | RECRUITING | NA
100 Participants

Improving the Mental Health of Home Health Aides

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-27
Completion: 2026-06-30
Conditions
Mental Health Issue
Interventions
BEHAVIORAL
No Results Yet
NCT06064890 | RECRUITING | PHASE1/PHASE2
9 Participants

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-30
Completion: 2026-04-01
Conditions
Frontotemporal Dementia FTD FTD-GRN Dementia, Frontotemporal
Interventions
PROCEDURE GENETIC
No Results Yet
NCT06058598 | ACTIVE_NOT_RECRUITING | NA
168 Participants

Exercise Training in Patients With Glaucoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-01
Completion: 2026-03-31
Conditions
Glaucoma, Open-Angle Exercise Training Microvascular Health
Interventions
OTHER
No Results Yet
NCT06056830 | RECRUITING | PHASE3
383 Participants

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-21
Completion: 2026-09-30
Conditions
Prostate Cancer Prostatic Neoplasms
Interventions
DRUG
No Results Yet
NCT06056297 | RECRUITING | PHASE3
176 Participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-06-06
Completion: 2027-09-30
Conditions
Neutropenia
Interventions
DRUG
No Results Yet
NCT06052072 | RECRUITING | NA
50 Participants

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-02-20
Completion: 2026-06-30
Conditions
Group 2 Pulmonary Hypertension Heart Failure
Interventions
DEVICE
No Results Yet
NCT06049576 | SUSPENDED | PHASE1
30 Participants

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-06
Completion: 2026-03-14
Conditions
Clear Cell Renal Cell Carcinoma Sarcomatoid Renal Cell Carcinoma Stage III Renal Cell Cancer AJCC v8 Stage IV Renal Cell Cancer AJCC v8
Interventions
PROCEDURE BIOLOGICAL DRUG
No Results Yet
NCT06048757 | COMPLETED | NA
62 Participants

Mobile Application-delivered Resistance Program for Children and Adolescents With Type 1 Diabetes (Diactive-1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-20
Completion: 2024-03-01
Conditions
Type 1 Diabetes
Interventions
DEVICE
No Results Yet
NCT06044337 | ENROLLING_BY_INVITATION | PHASE3
322 Participants

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-03
Completion: 2029-06-26
Conditions
Subacute Cutaneous Lupus Erythematosus Chronic Cutaneous Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT06041256 | COMPLETED | PHASE1/PHASE2
97 Participants

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-18
Completion: 2024-10-25
Conditions
Corneal Edema Corneal Endothelial Dysfunction
Interventions
COMBINATION_PRODUCT BIOLOGICAL DRUG
Results Available
NCT06036524 | ACTIVE_NOT_RECRUITING | NA
52 Participants

Multi-modal Imaging of Myofascial Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-24
Completion: 2025-04-30
Conditions
Myofascial Pain
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06030466 | ENROLLING_BY_INVITATION | NA
60 Participants

Medical Students' Acceptance and Learning Efficacy With Physical and Virtual Standardized Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-01
Completion: 2026-12-31
Conditions
Education, Medical
Interventions
OTHER
No Results Yet
NCT06025578 | ACTIVE_NOT_RECRUITING | PHASE3
1092 Participants

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-25
Completion: 2027-12-27
Conditions
Progressive Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT06016855 | RECRUITING | PHASE4
6 Participants

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-31
Completion: 2027-05-28
Conditions
Digestive System Neuroendocrine Tumor G1 Digestive System Neuroendocrine Tumor G2 Metastatic Digestive System Neuroendocrine Neoplasm Metastatic Malignant Neoplasm in the Liver Pancreatic Neuroendocrine Tumor G1 Pancreatic Neuroendocrine Tumor G2
Interventions
PROCEDURE DRUG
No Results Yet
NCT06001632 | COMPLETED | NA
50 Participants

Changes in Muscle Strength, Inflammatory Markers, and Body Composition in Response to Alternate Day Fasting Combined With Krill Oil Supplementation in Adults With Overweight and Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-03-28
Completion: 2025-10-01
Conditions
Obesity Associated Disorder
Interventions
DIETARY_SUPPLEMENT
No Results Yet
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