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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06177197 | RECRUITING | NA
458 Participants

Bronchiolitis Clearance Airways With Seaserum

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-10
Completion: 2027-11-01
Conditions
Bronchiolitis Acute
Interventions
DEVICE
No Results Yet
NCT06177067 | RECRUITING | PHASE1
24 Participants

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-19
Completion: 2026-07-31
Conditions
Refractory Acute Myeloid Leukemia Relapsed Acute Myeloid Leukemia Acute Leukemia of Ambiguous Lineage
Interventions
DRUG
No Results Yet
NCT06173323 | RECRUITING | NA
128 Participants

A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-16
Completion: 2027-03-31
Conditions
Decision Making, Shared Family Caregiving Chronic Kidney Disease
Interventions
BEHAVIORAL
No Results Yet
NCT06168604 | RECRUITING | NA
440 Participants

Evaluating the Efficacy of the Pain Identification and Communication Toolkit

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-14
Completion: 2028-02-01
Conditions
Caregiver Burden Cognitive Impairment Dementia Alzheimer Disease Pain, Chronic
Interventions
BEHAVIORAL
No Results Yet
NCT06164730 | RECRUITING | PHASE1
85 Participants

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-30
Completion: 2026-08-31
Conditions
Heterozygous Familial Hypercholesterolemia Premature Coronary Heart Disease
Interventions
DRUG
No Results Yet
NCT06162377 | RECRUITING | PHASE4
25 Participants

Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-10
Completion: 2026-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT06159790 | SUSPENDED | PHASE3
218 Participants

A Study to Compare Efficacy, Safety, and Immunogenicity of GME751 and EU-authorized Keytruda in Adult Participants With Untreated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-29
Completion: 2026-02-28
Conditions
Metastatic NSCLC
Interventions
DRUG
No Results Yet
NCT06158854 | RECRUITING | PHASE1/PHASE2
76 Participants

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-01
Completion: 2031-09-30
Conditions
Immunoglobulin Light Chain (AL) Amyloidosis
Interventions
DRUG
No Results Yet
NCT06157840 | RECRUITING | NA
40 Participants

Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-25
Completion: 2026-04-30
Conditions
Opioid Use Disorder Poor Quality Sleep
Interventions
DEVICE
No Results Yet
NCT06154174 | RECRUITING | NA
1500 Participants

Choline to Improve Malnutrition and Enhance Cognition

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-05
Completion: 2026-06-30
Conditions
Severe Acute Malnutrition Cognitive Impairment Wasting Kwashiorkor
Interventions
DIETARY_SUPPLEMENT DRUG
No Results Yet
NCT06152705 | RECRUITING | NA
210 Participants

Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-16
Completion: 2027-10-01
Conditions
Depression Depressive Disorder, Major Depressive Episode
Interventions
DEVICE
No Results Yet
NCT06143774 | RECRUITING | PHASE1
30 Participants

Study of TRX-920 for Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-31
Completion: 2026-03-30
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06141720 | RECRUITING | NA
20 Participants

Feasibility of a Mindfulness Intervention for Endometriosis Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-30
Completion: 2026-06-30
Conditions
Endometriosis Pain Mindfulness
Interventions
BEHAVIORAL
No Results Yet
NCT06139328 | TERMINATED | PHASE2
160 Participants

IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-05
Completion: 2025-09-02
Conditions
Myocardial Infarction
Interventions
DRUG
No Results Yet
NCT06138184 | NOT_YET_RECRUITING | NA
68 Participants

Learning Theory Patient Education for Anticoagulants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-04-30
Completion: 2026-10-31
Conditions
Knowledge, Attitudes, Practice
Interventions
BEHAVIORAL
No Results Yet
NCT06137781 | COMPLETED | NA
35 Participants

Digital Prehabilitation for Patients Undergoing Major Elective Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-02-19
Completion: 2024-09-17
Conditions
Surgery
Interventions
BEHAVIORAL
Results Available
NCT06132113 | RECRUITING | PHASE1
55 Participants

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-22
Completion: 2027-02-09
Conditions
Neuroendocrine Neoplasms
Interventions
DRUG
No Results Yet
NCT06130553 | RECRUITING | PHASE1/PHASE2
234 Participants

A Study of AZD3470, a PRMT5 Inhibitor, in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-18
Completion: 2026-02-26
Conditions
Advanced Solid Tumors That Are MTAP Deficient
Interventions
DRUG
No Results Yet
NCT06130280 | RECRUITING | PHASE2
32 Participants

A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-08
Completion: 2026-11-30
Conditions
Colorectal Cancer Liver Metastases
Interventions
RADIATION
No Results Yet
NCT06127199 | RECRUITING | NA
656 Participants

Contraceptive Efficacy Study of Ovaprene

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-19
Completion: 2026-06-30
Conditions
Contraception
Interventions
DEVICE
No Results Yet
NCT06125977 | ACTIVE_NOT_RECRUITING
73 Participants

Impact of Non-Exudative Type 1 MNV on AMD Progression

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-01-30
Completion: 2027-08-31
Conditions
Age-Related Macular Degeneration Neovascularization, Choroidal
No Results Yet
NCT06121505 | RECRUITING | PHASE2
114 Participants

Phase II Trial: Low-Dose Radiation + SBRT + Sintilimab + Chemotherapy vs. Sintilimab + Chemotherapy in Locally Advanced or Metastatic Squamous Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-03-01
Completion: 2027-02-28
Conditions
Lung Squamous Cell Carcinoma
Interventions
RADIATION DRUG
No Results Yet
NCT06121323 | COMPLETED | NA
12 Participants

Physiological Effects of Lactate in Individuals With Chronic Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-22
Completion: 2025-01-16
Conditions
Heart Failure, Systolic
Interventions
OTHER
No Results Yet
NCT06118255 | ACTIVE_NOT_RECRUITING | PHASE3
25 Participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-21
Completion: 2026-09-03
Conditions
Dravet Syndrome
Interventions
DRUG
No Results Yet
NCT06112379 | ACTIVE_NOT_RECRUITING | PHASE3
1902 Participants

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-14
Completion: 2028-11-20
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT06110793 | RECRUITING | PHASE1/PHASE2
49 Participants

A Study of Lenvatinib, Pembrolizumab, and Fulvestrant in People With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-29
Completion: 2026-11-30
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT06109285 | ACTIVE_NOT_RECRUITING | NA
16 Participants

Validation of i-ROP DL to Detect More Than Mild ROP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-06-25
Completion: 2026-02-01
Conditions
Retinopathy of Prematurity ROP
Interventions
DEVICE
No Results Yet
NCT06108609 | COMPLETED
100 Participants

Validation of the French Version of the Hearing Aid Benefit Measurement COSI and IOI-HA Questionnaires

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-05-16
Completion: 2024-08-08
Conditions
Hearing Impairment
Interventions
OTHER
No Results Yet
NCT06107725 | TERMINATED | PHASE2/PHASE3
2 Participants

Maimonides Minocycline in Stroke Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-01
Completion: 2024-05-09
Conditions
Stroke, Acute Ischemic Stroke Hemorrhagic Stroke Mortality Morbidity
Interventions
DRUG
Results Available
NCT06102057 | RECRUITING | PHASE2
110 Participants

PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-07-01
Completion: 2026-06-30
Conditions
Stage III Non-small Cell Lung Cancer Locally Advanced Unresectable
Interventions
RADIATION DRUG
No Results Yet
NCT06098508 | COMPLETED | NA
3 Participants

Osteopathic Manual Treatment for Hemiplegic Shoulder Pain and Upper Extremity Function in Stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-07-23
Completion: 2025-11-10
Conditions
Hemiplegic Shoulder Pain Osteopathic Manipulative Treatment
Interventions
OTHER
No Results Yet
NCT06094634 | ACTIVE_NOT_RECRUITING | NA
562 Participants

IGHID 12219 - A Brief Alcohol Intervention for PrEP Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-03
Completion: 2027-01-31
Conditions
Unhealthy Alcohol Use
Interventions
BEHAVIORAL
No Results Yet
NCT06093425 | NOT_YET_RECRUITING | PHASE3
820 Participants

Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-06-30
Completion: 2029-10-01
Conditions
Gastric Cancer Gastroesophageal-junction Cancer Advanced Cancer
Interventions
DRUG
No Results Yet
NCT06075953 | RECRUITING | PHASE2
400 Participants

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-02-17
Completion: 2028-11-30
Conditions
Ductal Carcinoma in Situ
Interventions
DRUG
No Results Yet
NCT06072378 | RECRUITING | NA
50 Participants

The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-31
Completion: 2028-09-01
Conditions
Memory, Short-Term
Interventions
BEHAVIORAL
No Results Yet
NCT06071221 | RECRUITING | NA
100 Participants

Improving the Mental Health of Home Health Aides

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-27
Completion: 2026-06-30
Conditions
Mental Health Issue
Interventions
BEHAVIORAL
No Results Yet
NCT06064890 | RECRUITING | PHASE1/PHASE2
9 Participants

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-30
Completion: 2026-04-01
Conditions
Frontotemporal Dementia FTD FTD-GRN Dementia, Frontotemporal
Interventions
PROCEDURE GENETIC
No Results Yet
NCT06058598 | ACTIVE_NOT_RECRUITING | NA
168 Participants

Exercise Training in Patients With Glaucoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-01
Completion: 2026-03-31
Conditions
Glaucoma, Open-Angle Exercise Training Microvascular Health
Interventions
OTHER
No Results Yet
NCT06056830 | RECRUITING | PHASE3
383 Participants

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-21
Completion: 2026-09-30
Conditions
Prostate Cancer Prostatic Neoplasms
Interventions
DRUG
No Results Yet
NCT06056297 | RECRUITING | PHASE3
176 Participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-06-06
Completion: 2027-09-30
Conditions
Neutropenia
Interventions
DRUG
No Results Yet
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