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Clinical Trials

Showing trials with last updates posted in 2025.

NCT04536168 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-12-17
No Results Yet
NCT04534010 | TERMINATED | NA
6 Participants

Decellularized, Whole Donor Nipple-Areola Complex Reconstruction Grafts

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-04-28
Completion: 2024-11-21
Conditions
Breast Cancer
Interventions
DEVICE
Results Available
NCT04532177 | ACTIVE_NOT_RECRUITING | NA
15 Participants

Stereotactic Body Radiation Therapy (SBRT) for Invasive Breast Cancer Patients Not Undergoing Definitive Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-08-19
Completion: 2027-08-31
Conditions
Breast Cancer
Interventions
RADIATION
No Results Yet
NCT04508907 | ACTIVE_NOT_RECRUITING | PHASE4
200 Participants

A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-09-10
Completion: 2025-11-01
Conditions
Hepatitis C Kidney Transplant; Complications Heart Transplant Infection
Interventions
DRUG
No Results Yet
NCT04482309 | RECRUITING | PHASE2
468 Participants

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-08-18
Completion: 2027-07-30
Conditions
Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT04472702 | RECRUITING | NA
90 Participants

Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-02-02
Completion: 2026-01-01
Conditions
Knee Osteoarthritis
Interventions
PROCEDURE
No Results Yet
NCT04458779 | COMPLETED | NA
71 Participants

Continuous Positive Airway Pressure on Acute Stroke and Obstructive Sleep Apnea

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-07-09
Completion: 2024-12-31
Conditions
Stroke, Acute Obstructive Sleep Apnea
Interventions
DEVICE
No Results Yet
NCT04423523 | COMPLETED
88 Participants

Plasma Levels of Danger-Associated Molecular Patterns in Young Children After Cardiac Surgery Under Cardiopulmonary Bypass

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-09-02
Completion: 2023-06-27
Conditions
Cardiac Surgical Procedure
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04422912 | RECRUITING | PHASE1/PHASE2
40 Participants

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-09-29
Completion: 2029-01-31
Conditions
Pemphigus Vulgaris
Interventions
BIOLOGICAL
No Results Yet
NCT04416568 | ACTIVE_NOT_RECRUITING | PHASE2
45 Participants

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-08-14
Completion: 2025-07-17
Conditions
Malignant Rhabdoid Tumor Rhabdoid Tumor of the Kidney Epithelioid Sarcoma Chordoma (Poorly Differentiated or De-differentiated) Atypical Teratoid/Rhabdoid Tumor Other INI1 Negative Tumors (With PI Approval) Other SMARCA4-deficient Malignant Tumors (With PI Approval)
Interventions
DRUG
No Results Yet
NCT04414930 | COMPLETED | PHASE2
68 Participants

Pharmacologic Augmentation of Targeted Cognitive Training in Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-11-09
Completion: 2024-12-30
Conditions
Schizophrenia Schizoaffective Disorder
Interventions
DRUG
Results Available
NCT04414111 | ACTIVE_NOT_RECRUITING
180 Participants

Highly Suppressive Treg in Delayed and Slow Graft Function After Kidney Transplantation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-12-07
Completion: 2026-07-31
Conditions
DGF Kidney Transplant; Complications
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04396821 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
150 Participants

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-05-28
Completion: 2026-05-30
Conditions
Advanced Cancer Gastric Cancer Gastroesophageal-junction Cancer Pancreatic Cancer
Interventions
DRUG
No Results Yet
NCT04394325 | COMPLETED | NA
80 Participants

Digi-Do - a Digital Information Tool to Help Patients Diagnosed With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-09-01
Completion: 2022-06-01
Conditions
Breast Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT04392401 | RECRUITING
200 Participants

COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric Non Interventional Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-05-11
Completion: 2026-04-30
Conditions
Intensive Care Unit SARS-Cov-2
Interventions
BIOLOGICAL
No Results Yet
NCT04389281 | RECRUITING | PHASE1
20 Participants

X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-08
Completion: 2028-09-30
Conditions
Advanced Solid Tumor Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04375514 | TERMINATED | PHASE1/PHASE2
43 Participants

Study of ARO-ENaC in Healthy Volunteers and in Patients With Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-07-30
Completion: 2021-05-09
Conditions
Cystic Fibrosis, Pulmonary
Interventions
DRUG
Results Available
NCT04369560 | RECRUITING | EARLY_PHASE1
42 Participants

Virtual Histology of the Bladder Wall for Bladder Cancer Staging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-23
Completion: 2028-01-30
Conditions
Urinary Bladder Neoplasms
Interventions
DIAGNOSTIC_TEST DRUG
No Results Yet
NCT04367181 | COMPLETED | NA
100 Participants

DCS Study in Extremely Premature Newborns

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2019-03-15
Completion: 2023-05-31
Conditions
Premature Birth Extremely Low Birth Weight Infant, Small for Gestational Age Intracerebral Hemorrhage
Interventions
DEVICE
No Results Yet
NCT04349267 | COMPLETED | PHASE1/PHASE2
44 Participants

Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-07-14
Completion: 2024-08-22
Conditions
Advanced Solid Tumor
Interventions
BIOLOGICAL
Results Available
NCT04331886 | COMPLETED
199 Participants

An Observational Study of Patients With Coronavirus Disease 2019

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-04-13
Completion: 2020-08-20
Conditions
COVID-19 Coronavirus
No Results Yet
NCT04323904 | RECRUITING
200 Participants

Hantavirus Registry - HantaReg

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-03-04
Completion: 2030-03-31
Conditions
Hemorrhagic Fever With Renal Syndrome Nephropathia Epidemica Hantavirus Cardiopulmonary Syndrome Hantavirus Infections
Interventions
OTHER
No Results Yet
NCT04318886 | ACTIVE_NOT_RECRUITING | PHASE3
412 Participants

Lay Coach-Led Early Palliative Care for Underserved Advanced Cancer Caregivers: The Project ENABLE Cornerstone RCT

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-01-07
Completion: 2025-12-31
Conditions
Cancer Metastatic Family Members
Interventions
BEHAVIORAL
No Results Yet
NCT04312243 | TERMINATED | PHASE2
24 Participants

NO Prevention of COVID-19 for Healthcare Providers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-04-07
Completion: 2022-01-10
Conditions
Coronavirus Infections Healthcare Associated Infection
Interventions
DRUG
No Results Yet
NCT04305457 | TERMINATED | PHASE2
70 Participants

Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-03-21
Completion: 2023-08-23
Conditions
Coronavirus Infections Pneumonia, Viral Acute Respiratory Distress Syndrome
Interventions
DRUG
No Results Yet
NCT04293224 | RECRUITING | NA
70 Participants

Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-08-01
Completion: 2026-03-31
Conditions
Obesity Body Weight
Interventions
OTHER
No Results Yet
NCT04288674 | RECRUITING
200 Participants

Leptospirosis Registry - LeptoScope

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-03-04
Completion: 2030-02-28
Conditions
Leptospirosis
Interventions
OTHER
No Results Yet
NCT04280029 | ACTIVE_NOT_RECRUITING | NA
418 Participants

SELUTION SLR™ 014 In-stent Restenosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-07-06
Completion: 2025-08-15
Conditions
Coronary Restenosis
Interventions
DEVICE
No Results Yet
NCT04257500 | COMPLETED | PHASE4
22 Participants

Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-09-03
Completion: 2025-08-22
Conditions
Polycystic Ovary Syndrome
Interventions
DRUG
No Results Yet
NCT04246177 | ACTIVE_NOT_RECRUITING | PHASE3
480 Participants

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-05-22
Completion: 2025-08-19
Conditions
Carcinoma, Hepatocellular
Interventions
DRUG BIOLOGICAL PROCEDURE
No Results Yet
NCT04222504 | ACTIVE_NOT_RECRUITING | NA
500 Participants

Community-based Venues for Delivery of Healthcare Services: Proof of Concept Pilot

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-02-08
Completion: 2026-03-31
Conditions
Pre-Exposure Prophylaxis STI Contraceptive Usage
Interventions
BEHAVIORAL
No Results Yet
NCT04196413 | RECRUITING | PHASE1
97 Participants

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-06-04
Completion: 2028-07-31
Conditions
Glioma of Spinal Cord Glioma of Brainstem
Interventions
DRUG
No Results Yet
NCT04168008 | COMPLETED | NA
151 Participants

A Peer-Led Intervention to Improve Postpartum Retention in HIV Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-03-03
Completion: 2025-09-08
Conditions
HIV/AIDS
Interventions
BEHAVIORAL
No Results Yet
NCT04132544 | COMPLETED | NA
952 Participants

Risk Factors for Falls After Intervention of the Urgent Medical Assistance Service (SAMU) in the Elderly Person at Home

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2019-09-01
Completion: 2024-04-30
Conditions
Elderly
Interventions
OTHER
No Results Yet
NCT04128761 | COMPLETED | NA
124 Participants

Decreasing the Temporal Window in Individuals With Alcohol Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-09-21
Completion: 2024-05-28
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
Results Available
NCT04128748 | RECRUITING | PHASE1/PHASE2
52 Participants

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-05-27
Completion: 2027-12-31
Conditions
Acute Myeloid Leukemia Blasts More Than 10 Percent of Bone Marrow Nucleated Cells High Risk Myelodysplastic Syndrome Recurrent Acute Myeloid Leukemia Recurrent Myelodysplastic Syndrome Refractory Acute Myeloid Leukemia Refractory Myelodysplastic Syndrome
Interventions
DRUG
No Results Yet
NCT04126824 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
28 Participants

Effect of Addition of Steroids on Duration of Analgesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-01-06
Completion: 2026-08-02
Conditions
Uterine Fibroids Adenomyosis
Interventions
DRUG OTHER
No Results Yet
NCT04114669 | COMPLETED | NA
401 Participants

Behavioral Economics Trial To Enhance Regulation of Blood Pressure (BETTER-BP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-07-14
Completion: 2025-05-12
Conditions
High Blood Pressure
Interventions
BEHAVIORAL
No Results Yet
NCT04109807 | SUSPENDED | NA
18 Participants

Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2019-12-16
Completion: 2027-08-31
Conditions
Asthma, Allergic
Interventions
OTHER
No Results Yet
NCT04100057 | RECRUITING | NA
150 Participants

Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-08-31
Completion: 2026-04-30
Conditions
Alzheimer Disease Mild Cognitive Impairment Neuropsychiatric Symptoms Sleep Disturbance
Interventions
BEHAVIORAL
No Results Yet
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