Clinical Trials

Showing trials with last updates posted in 2025.

NCT06807606 | RECRUITING | PHASE2
35 Participants

Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-03-03
Completion: 2027-11-30
Conditions
Hematologic Malignancies
Interventions
DRUG
No Results Yet
NCT06800183 | WITHDRAWN | EARLY_PHASE1
0 Participants

Topical Tartrazine for Improved Skin Structure Visualization in Dermatology

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2026-05-11
Completion: 2026-12-31
Conditions
Healthy Dermoscopy Optical Imaging
Interventions
DRUG
No Results Yet
NCT06785636 | RECRUITING | PHASE1/PHASE2
252 Participants

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-02-07
Completion: 2028-06-30
Conditions
mCRPC (Metastatic Castration-resistant Prostate Cancer) Genital Neoplasms, Male Urogenital Neoplasms Urogenital Cancers Prostatic Diseases Prostatic Neoplasms Male Urogenital Diseases Neoplasms Neoplasms by Site Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06784349 | RECRUITING | PHASE1
136 Participants

ALN-APOC3 in Adult Participants With Dyslipidemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-27
Completion: 2026-02-25
Conditions
Dyslipidemia
Interventions
DRUG
No Results Yet
NCT06782295 | RECRUITING | PHASE4
170 Participants

The Use of CCK vs PS in Revision TKAs

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-07-01
Completion: 2028-07-01
Conditions
Aseptic Loosening of Prosthetic Joint Instability of Prosthetic Joint Reimplantation for Periprosthetic Joint Infection Femoral Revision Indicated Tibial Component Revision
Interventions
DEVICE
No Results Yet
NCT06780137 | RECRUITING | PHASE1/PHASE2
242 Participants

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-02-27
Completion: 2029-08-31
Conditions
Small Cell Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06779630 | RECRUITING | NA
150 Participants

Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions (BIOFLOW-48) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-07-18
Completion: 2027-09-30
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT06745921 | ACTIVE_NOT_RECRUITING | PHASE1
30 Participants

Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-02-24
Completion: 2026-10-01
Conditions
West Nile Viral Infection
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06745063 | RECRUITING | PHASE2
50 Participants

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-05-30
Completion: 2028-12-31
Conditions
Obesity Vascular Health
Interventions
DRUG
No Results Yet
NCT06742801 | RECRUITING | NA
119 Participants

Onyx™ Liquid Embolic IDE Clinical Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-05-09
Completion: 2026-11-30
Conditions
Peripheral Arterial Hemorrhage Trauma GI Bleed Ulcer Hemorrhage
Interventions
DEVICE
No Results Yet
NCT06738407 | NOT_YET_RECRUITING | PHASE4
760 Participants

Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-11-28
Completion: 2028-05-31
Conditions
Gonorrhea Chlamydia Syphilis Sexually Transmitted Infections (STIs)
Interventions
DRUG
No Results Yet
NCT06735209 | ACTIVE_NOT_RECRUITING | PHASE1
22 Participants

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-07-23
Completion: 2027-02-01
Conditions
Malaria
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06733935 | RECRUITING | PHASE1/PHASE2
144 Participants

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-11-04
Completion: 2028-10-31
Conditions
Systemic Sclerosis Idiopathic Inflammatory Myopathies Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions
DRUG
No Results Yet
NCT06732401 | RECRUITING | PHASE3
630 Participants

Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-08-07
Completion: 2028-06-30
Conditions
Lung Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06731504 | RECRUITING | EARLY_PHASE1
10 Participants

HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-12-31
Completion: 2027-12-31
Conditions
Hematologic Malignancy
Interventions
DRUG
No Results Yet
NCT06730750 | RECRUITING | PHASE1/PHASE2
360 Participants

A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-02-12
Completion: 2026-09-05
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06727552 | RECRUITING | PHASE2
120 Participants

A Study of Barzolvolimab in Patients With Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-07
Completion: 2026-10-31
Conditions
Atopic Dermatitis
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06726265 | RECRUITING | PHASE3
756 Participants

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-03-21
Completion: 2027-06-30
Conditions
Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Interventions
BIOLOGICAL DRUG OTHER
No Results Yet
NCT06726148 | RECRUITING | PHASE1/PHASE2
280 Participants

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-04-03
Completion: 2028-09-25
Conditions
Advanced HR+/HER2- Breast Cancer Advanced CCNE1-amplified Solid Tumors
Interventions
DRUG
No Results Yet
NCT06726083 | NOT_YET_RECRUITING | NA
180 Participants

Improving Dietary Quality and Social Engagement Through a Virtual Nutrition and Teaching Kitchen Intervention Among Older Veterans With Impaired Mobility

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2026-01-01
Completion: 2029-12-31
Conditions
Impaired Mobility
Interventions
BEHAVIORAL
No Results Yet
NCT06724809 | RECRUITING | PHASE3
21 Participants

Efficacy, Safety, PK, PD, and ADA of Eculizumab in Chinese Adults With NMOSD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-16
Completion: 2026-12-07
Conditions
NMOSD Neuromyelitis Optica Spectrum Disorders
Interventions
DRUG
No Results Yet
NCT06721156 | RECRUITING | PHASE2
350 Participants

A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-16
Completion: 2026-12-31
Conditions
Alzheimer Disease Dementia
Interventions
DRUG
No Results Yet
NCT06718140 | ENROLLING_BY_INVITATION | PHASE1
25 Participants

tFUS for Memory in mNCD and Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-04-01
Completion: 2026-12-01
Conditions
Mild Neurocognitive Disorder Healthy Aging
Interventions
DEVICE
No Results Yet
NCT06718101 | RECRUITING | PHASE2
80 Participants

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-19
Completion: 2027-05-31
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06709521 | RECRUITING | PHASE4
150 Participants

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-02-12
Completion: 2026-06-30
Conditions
Bacterial Infection
Interventions
DRUG
No Results Yet
NCT06707142 | RECRUITING | PHASE1
124 Participants

A Trial in Healthy Adult Participants to Evaluate the Safety, Tolerability, and Behavior in the Body of TBD11

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-05
Completion: 2026-02-28
Conditions
Healthy Adult Participants
Interventions
DRUG
No Results Yet
NCT06706622 | RECRUITING | PHASE3
360 Participants

A Trial of Lu AF82422 in Participants With Multiple System Atrophy (MSA)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-03
Completion: 2028-02-17
Conditions
Multiple System Atrophy
Interventions
DRUG
No Results Yet
NCT06692907 | RECRUITING | PHASE2
72 Participants

Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-03-31
Completion: 2026-02-20
Conditions
Escherichia Infection
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06691867 | RECRUITING | NA
155 Participants

Integrative Training Program for Pediatric Sickle Cell Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-08
Completion: 2027-08-31
Conditions
Sickle Cell Disease
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06679985 | RECRUITING | PHASE2
72 Participants

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-20
Completion: 2027-09-30
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
NCT06679946 | ENROLLING_BY_INVITATION | PHASE3
700 Participants

A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-03
Completion: 2028-05-30
Conditions
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT06678490 | RECRUITING
278 Participants

Support C Post-Market Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2025-07-09
Completion: 2027-05-31
Conditions
Coronary Arteriosclerosis
No Results Yet
NCT06676319 | RECRUITING | PHASE2
1000 Participants

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-11-07
Completion: 2027-10-12
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06675929 | ACTIVE_NOT_RECRUITING | PHASE2
28 Participants

A Study to Test How Well BI 770371 is Tolerated by People With Cirrhosis Caused by a Liver Disease Called MASH

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-20
Completion: 2026-01-12
Conditions
Compensated Liver Cirrhosis Metabolic Dysfunction Associated Steatohepatitis (MASH)
Interventions
DRUG
No Results Yet
NCT06672588 | RECRUITING | NA
80 Participants

Magnetic Seizure Therapy for Schizophrenia - Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-04-22
Completion: 2028-11-30
Conditions
Treatment Resistant Schizophrenia Schizophrenia Schizoaffective Disorder
Interventions
DEVICE
No Results Yet
NCT06671886 | RECRUITING | NA
32 Participants

NAFLD Clinical Care Pathway

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-02-02
Completion: 2028-01-31
Conditions
NAFLD MASLD
Interventions
BEHAVIORAL
No Results Yet
NCT06667700 | RECRUITING | PHASE3
3082 Participants

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-02
Completion: 2031-01-26
Conditions
Coronavirus Disease (COVID-19)
Interventions
DRUG
No Results Yet
NCT06663358 | RECRUITING
100 Participants

A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2024-11-06
Completion: 2029-11-30
Conditions
Fabry Disease
Interventions
DRUG
No Results Yet
NCT06663020 | ACTIVE_NOT_RECRUITING
248 Participants

Impact of Smoking Cessation Duration on Postoperative Complications in Lung Cancer Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2023-06-15
Completion: 2024-11-15
Conditions
Smoking Cessation Lung Cancer (NSCLC) Postoperative Complication
Interventions
BEHAVIORAL
No Results Yet
NCT06662539 | ACTIVE_NOT_RECRUITING | PHASE2
493 Participants

Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-12-09
Completion: 2025-09-30
Conditions
Obesity
Interventions
DRUG
No Results Yet
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