Clinical Trials
Showing trials with last updates posted in 2025.
80
Participants
Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2018-09-01
Completion:
2030-06-30
Conditions
Healthy
Interventions
DEVICE
No Results Yet
48
Participants
Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2017-05-25
Completion:
2021-07-16
Conditions
Adult T-Cell Leukemia/Lymphoma
Anaplastic Large Cell Lymphoma, ALK-Negative
Anaplastic Large Cell Lymphoma, ALK-Positive
Angioimmunoblastic T-Cell Lymphoma
Ann Arbor Stage II Noncutaneous Anaplastic Large Cell Lymphoma
Ann Arbor Stage III Noncutaneous Anaplastic Large Cell Lymphoma
Ann Arbor Stage IV Noncutaneous Anaplastic Large Cell Lymphoma
Enteropathy-Associated T-Cell Lymphoma
Hepatosplenic T-Cell Lymphoma
Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Peripheral T-Cell Lymphoma, Not Otherwise Specified
Interventions
DRUG
OTHER
250
Participants
Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2017-08-11
Completion:
2026-01-01
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
100
Participants
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2017-03-13
Completion:
2026-09-30
Conditions
Polycystic Ovary Syndrome
Interventions
DRUG
OTHER
No Results Yet
1000
Participants
COMparison of Physiological Algorithms for Real-time Evaluation of Atrial Fibrillation
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2016-12-01
Completion:
2026-12-31
Conditions
Atrial Fibrillation
Abnormal Heart Rhythms
No Results Yet
18
Participants
Ipilimumab and Nivolumab in Leptomeningeal Metastases
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2018-02-15
Completion:
2021-07-22
Conditions
Leptomeningeal Carcinomatosis
Interventions
DRUG
154
Participants
A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2016-10-20
Completion:
2024-11-22
Conditions
Advanced Solid Tumors
Triple Negative Breast Cancer
Chordoma and Alveolar Soft Part Sarcoma
Interventions
DRUG
No Results Yet
29
Participants
Safety and Effectiveness of the Sight Sciences VISCO™360 Versus SLT in Primary Open Angle Glaucoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2017-01-23
Completion:
2019-01-17
Conditions
Open-Angle Glaucoma
Interventions
DEVICE
187
Participants
Postmarketing Prospective Study of Melanoma Patients Treated With IMLYGIC® to Characterize Risk of Herpetic Infection
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2017-08-10
Completion:
2026-01-30
Conditions
Melanoma
Herpetic Infection
No Results Yet
18
Participants
Cu64-DOTA-trastuzumab PET and Markers Predicting Response to Neoadjuvant Trastuzumab + Pertuzum in HER2+ Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2016-07-15
Completion:
2020-07-02
Conditions
HER2 Positive Breast Carcinoma
Stage IIIA Breast Cancer
Stage IIIB Breast Cancer
Stage IIIC Breast Cancer
Interventions
RADIATION
OTHER
BIOLOGICAL
PROCEDURE
1133
Participants
Postoperative Hip Precautions After Total Hip Arthroplasty Via the Posterior Approach: A Prospective Randomized Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2016-01-31
Completion:
2025-07-21
Conditions
Osteoarthritis
Degenerative Joint Disease
Interventions
OTHER
No Results Yet
171
Participants
Molecular Imaging of Primary Amyloid Cardiomyopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2016-04-01
Completion:
2027-12-31
Conditions
Amyloidosis, Primary
Cardiomyopathy
Interventions
RADIATION
DEVICE
No Results Yet
320
Participants
Study of Pembrolizumab (MK-3475) and Pembrolizumab With Other Investigational Agents in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2016-02-10
Completion:
2025-11-15
Conditions
Bladder Cancer
Interventions
BIOLOGICAL
No Results Yet
476
Participants
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2015-11-13
Completion:
2026-06-30
Conditions
Neurofibromatosis 1
Plexiform Neurofibromas
No Results Yet
30
Participants
Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2025-11-19
Completion:
2026-12-01
Conditions
Intractable Pain
Palliative Care
Interventions
DRUG
No Results Yet
41
Participants
Preliminary Testing of the MD Anderson Symptom Inventory (Adolescent Version)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2016-11-09
Completion:
2026-04-30
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Interventions
OTHER
No Results Yet
700
Participants
Studies of Dermatologic Diseases Biospecimen Acquisition Protocol
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2015-06-19
Completion:
2027-01-31
Conditions
Dermatologic Conditions
Healthy Volunteers
Normal Volunteers
Carcinoma, Merkel Cell
No Results Yet
128
Participants
IAI Versus Sham as Prophylaxis Against Conversion to Neovascular AMD
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2015-06-30
Completion:
2019-03-31
Conditions
Age-Related Macular Degeneration
Interventions
DRUG
337
Participants
SPYRAL HTN-ON MED Study of Renal Denervation With the Symplicity Spyral™ Multi-electrode Renal Denervation System
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2015-07-22
Completion:
2022-08-18
Conditions
Hypertension
Vascular Diseases
Cardiovascular Diseases
Interventions
DEVICE
PROCEDURE
600
Participants
A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2015-11-23
Completion:
2033-06-30
Conditions
Stage III Cutaneous Melanoma AJCC v7
Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions
PROCEDURE
BIOLOGICAL
No Results Yet
50
Participants
Standardized Prenatal Clinical Care for LUTO
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2014-12-31
Completion:
2026-11-30
Conditions
Urethral Obstruction
Interventions
PROCEDURE
No Results Yet
20
Participants
Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2015-11-11
Completion:
2022-03-06
Conditions
Breast Cancer
Colon Cancer
Extrahepatic Bile Duct Cancer
Gallbladder Cancer
Gastrointestinal Cancer
Liver and Intrahepatic Biliary Tract Cancer
Lung Cancer
Metastatic Cancer
Pancreatic Cancer
Rectal Cancer
Thyroid Gland Medullary Carcinoma
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
PROCEDURE
OTHER
DRUG
130
Participants
A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2014-12-22
Completion:
2018-07-09
Conditions
Arthritis, Juvenile
Interventions
DRUG
18
Participants
Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2016-03-07
Completion:
2022-02-21
Conditions
Recurrent Anaplastic Astrocytoma
Recurrent Anaplastic Oligoastrocytoma
Recurrent Anaplastic Oligodendroglioma
Recurrent Glioblastoma
Recurrent Gliosarcoma
Recurrent Malignant Glioma
Recurrent WHO Grade III Glioma
Interventions
BIOLOGICAL
DRUG
OTHER
7
Participants
Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2014-04-30
Completion:
2019-10-31
Conditions
Non-Hodgkin's Lymphoma
B-Cell ALL
B-Cell CLL
Interventions
GENETIC
No Results Yet
72
Participants
Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2014-02-10
Completion:
2019-12-27
Conditions
Adult Acute Lymphoblastic Leukemia in Remission
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Adult Acute Myeloid Leukemia in Remission
Myelodysplastic Syndrome
Secondary Myelodysplastic Syndrome
Chronic Myelomonocytic Leukemia
Therapy-Related Myelodysplastic Syndrome
Interventions
DRUG
PROCEDURE
OTHER
571
Participants
Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2013-05-17
Completion:
2016-01-24
Conditions
Unresectable Pleural or Peritoneal Malignant Mesothelioma
Interventions
DRUG
613
Participants
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2013-03-22
Completion:
2027-01-01
Conditions
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma
Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7
Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions
DRUG
PROCEDURE
BIOLOGICAL
RADIATION
OTHER
No Results Yet
475
Participants
Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2013-02-28
Completion:
2026-02-28
Conditions
Breast Cancer
Lymphoma
Hodgkin's Lymphoma
Interventions
BEHAVIORAL
OTHER
DEVICE
No Results Yet
2000
Participants
Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2012-08-29
Completion:
2027-12-31
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Smoking
Smoking Cessation
Idiopathic Pulmonary Fibrosis (IPF)
Rheumatoid Arthritis-Associated Interstitial Lung Disease
Scleroderma-Associated Interstitial Lung Disease (SSC-ILD)
No Results Yet
1824
Participants
Transfusion of Prematures Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2012-12-31
Completion:
2020-01-31
Conditions
Infant, Newborn, Diseases
Infant, Extremely Low Birth Weight
Infant, Small for Gestational Age
Bronchopulmonary Dysplasia (BPD)
Anemia
Interventions
PROCEDURE
130
Participants
Effects of Treatments on Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2012-09-18
Completion:
2027-01-01
Conditions
Eczema
Dermatitis
Skin Diseases, Genetic
Dermatitis, Atopic
Skin Diseases
Interventions
DRUG
OTHER
No Results Yet
700
Participants
Evaluating a Social and Communication Intervention for Preschoolers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2012-07-31
Completion:
2026-02-28
Conditions
Autism Spectrum Disorder
Interventions
BEHAVIORAL
No Results Yet
129
Participants
Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2012-08-08
Completion:
2018-07-17
Conditions
Clear Cell Renal Cell Carcinoma
Stage IV Renal Cell Cancer AJCC v7
Interventions
PROCEDURE
DRUG
OTHER
48
Participants
SIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to Liver
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2011-10-31
Completion:
2022-07-07
Conditions
Stage IV Uveal Melanoma
Interventions
DEVICE
2000
Participants
Natural History and Development of Spondyloarthritis
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2011-08-12
Conditions
Arthritis
Spondylitis, Ankylosing
No Results Yet
53
Participants
Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2011-06-20
Completion:
2019-05-26
Conditions
Lung Adenocarcinoma
Lung Adenocarcinoma, Mixed Subtype
Lung Large Cell Carcinoma
Lung Squamous Cell Carcinoma
Minimally Invasive Lung Adenocarcinoma
Stage III Lung Non-Small Cell Cancer AJCC v7
Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions
RADIATION
DRUG
OTHER
62
Participants
Z-Endoxifen Hydrochloride in Treating Patients With Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2011-03-25
Completion:
2017-03-05
Conditions
HER2/Neu Positive
Recurrent Breast Carcinoma
Stage IIIC Breast Cancer AJCC v7
Stage IV Breast Cancer AJCC v6 and v7
Interventions
DRUG
OTHER
No Results Yet
692
Participants
Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2010-09-27
Completion:
2015-12-01
Conditions
Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube Mucinous Adenocarcinoma
Fallopian Tube Transitional Cell Carcinoma
Ovarian Brenner Tumor
Ovarian Clear Cell Adenocarcinofibroma
Ovarian Endometrioid Adenocarcinoma
Ovarian Mucinous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Ovarian Serous Adenocarcinoma
Ovarian Transitional Cell Carcinoma
Ovarian Undifferentiated Carcinoma
Primary Peritoneal Serous Adenocarcinoma
Stage IIA Fallopian Tube Cancer AJCC v6 and v7
Stage IIA Ovarian Cancer AJCC V6 and v7
Stage IIB Fallopian Tube Cancer AJCC v6 and v7
Stage IIB Ovarian Cancer AJCC v6 and v7
Stage IIC Fallopian Tube Cancer AJCC v6 and v7
Stage IIC Ovarian Cancer AJCC v6 and v7
Stage IIIA Fallopian Tube Cancer AJCC v7
Stage IIIA Ovarian Cancer AJCC v6 and v7
Stage IIIA Primary Peritoneal Cancer AJCC v7
Stage IIIB Fallopian Tube Cancer AJCC v7
Stage IIIB Ovarian Cancer AJCC v6 and v7
Stage IIIB Primary Peritoneal Cancer AJCC v7
Stage IIIC Fallopian Tube Cancer AJCC v7
Stage IIIC Ovarian Cancer AJCC v6 and v7
Stage IIIC Primary Peritoneal Cancer AJCC v7
Stage IV Fallopian Tube Cancer AJCC v6 and v7
Stage IV Ovarian Cancer AJCC v6 and v7
Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
BIOLOGICAL
DRUG
PROCEDURE
66
Participants
Veliparib and Temozolomide in Treating Patients With Acute Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2010-05-21
Completion:
2014-03-21
Conditions
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1
Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-KMT2A
Adult Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA
Adult B Acute Lymphoblastic Leukemia
Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Adult T Acute Lymphoblastic Leukemia
Alkylating Agent-Related Acute Myeloid Leukemia
Chronic Myelomonocytic Leukemia
Recurrent Adult Acute Lymphoblastic Leukemia
Recurrent Adult Acute Myeloid Leukemia
Secondary Acute Myeloid Leukemia
Interventions
OTHER
DRUG
No Results Yet
Showing 40 trials per page · Total 107903 trials