Clinical Trials
Showing trials with last updates posted in 2025.
82
Participants
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-03-12
Completion:
2029-03-31
Conditions
Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
Interventions
DRUG
RADIATION
OTHER
PROCEDURE
No Results Yet
2140
Participants
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-10-16
Completion:
2027-09-01
Conditions
Breast Cancer
Interventions
RADIATION
OTHER
No Results Yet
211
Participants
A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-04-17
Completion:
2021-02-26
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
DRUG
120
Participants
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-07-11
Completion:
2023-07-19
Conditions
Psoriasis
Interventions
DRUG
62
Participants
An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-12-05
Completion:
2026-04-30
Conditions
Malignant Neoplasm of Breast
Interventions
BEHAVIORAL
No Results Yet
223
Participants
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-04-26
Completion:
2026-03-31
Conditions
Castration Levels of Testosterone
Castration-Resistant Prostate Carcinoma
Metastatic Prostate Carcinoma in the Soft Tissue
Prostate Carcinoma Metastatic in the Bone
Stage IV Prostate Adenocarcinoma AJCC v7
Interventions
DRUG
OTHER
PROCEDURE
No Results Yet
629
Participants
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-03-23
Completion:
2024-04-15
Conditions
Urothelial Cancer
Interventions
DRUG
DEVICE
150
Participants
Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2020-11-03
Completion:
2025-12-16
Conditions
Advanced Bladder Carcinoma
Advanced Genitourinary System Carcinoma
Metastatic Bladder Carcinoma
Metastatic Genitourinary System Carcinoma
Stage III Bladder Cancer AJCC v8
Stage IV Bladder Cancer AJCC v8
Interventions
PROCEDURE
DRUG
No Results Yet
1214
Participants
AMPLATZER PFO Occluder Post Approval Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-01-31
Completion:
2030-02-05
Conditions
Stroke
Patent Foramen Ovale
Interventions
DEVICE
No Results Yet
689
Participants
Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-11-27
Completion:
2027-01-31
Conditions
Mantle Cell Lymphoma
Interventions
PROCEDURE
BIOLOGICAL
No Results Yet
108508
Participants
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-09-28
Completion:
2028-12-31
Conditions
Breast Screening
Interventions
PROCEDURE
OTHER
No Results Yet
146
Participants
DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-07-25
Completion:
2025-12-31
Conditions
Gliosarcoma
Recurrent Glioblastoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
32
Participants
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-07-09
Completion:
2025-08-15
Conditions
Glioblastoma
Gliosarcoma
MGMT-Unmethylated Glioblastoma
Recurrent Glioblastoma
Interventions
PROCEDURE
DRUG
RADIATION
No Results Yet
220
Participants
The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2024-04-16
Completion:
2027-08-31
Conditions
Intracranial Aneurysm
Interventions
DEVICE
No Results Yet
24
Participants
Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-05-01
Completion:
2024-11-15
Conditions
Pleural Malignant Mesothelioma
Interventions
OTHER
RADIATION
BIOLOGICAL
5399
Participants
Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex With Men and Are At Risk of HIV-1 Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2016-09-02
Completion:
2019-01-31
Conditions
Pre-Exposure Prophylaxis of HIV-1 Infection
Interventions
DRUG
300
Participants
Gastroschisis Outcomes of Delivery (GOOD) Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-02-23
Completion:
2029-03-31
Conditions
Gastroschisis
Interventions
OTHER
No Results Yet
132
Participants
Comparison Between Dexamethasone and Ibuprofen on Pain Prevention and Control Following Surgical Implant Placement
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2013-09-30
Completion:
2015-05-31
Conditions
Pain Measurement
Interventions
DRUG
189
Participants
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2016-11-23
Completion:
2027-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Hypopharyngeal Squamous Cell Carcinoma
Laryngeal Squamous Cell Carcinoma
Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant
Lip and Oral Cavity Squamous Cell Carcinoma
p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma
Stage III Hypopharyngeal Carcinoma AJCC v8
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Oral Cavity Verrucous Carcinoma
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVA Hypopharyngeal Carcinoma AJCC v8
Stage IVA Laryngeal Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8
Stage IVA Oral Cavity Verrucous Carcinoma
Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
DRUG
RADIATION
OTHER
No Results Yet
114
Participants
Novel Interventions for GWVI
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-06-01
Completion:
2023-09-29
Conditions
Gulf War Veteran's Illness
Interventions
BEHAVIORAL
100
Participants
Ovarian Tissue Cryopreservation in Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-03-16
Completion:
2040-01-22
Conditions
Cancer
Interventions
PROCEDURE
No Results Yet
56
Participants
Safety, Tolerability and Pharmacokinetics of AZD1775 (Adavosertib) Plus MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumours
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2015-12-28
Completion:
2019-04-22
Conditions
Advanced Solid Tumours
Interventions
DRUG
No Results Yet
21
Participants
Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-09-18
Completion:
2023-06-04
Conditions
Advanced Cervical Adenocarcinoma
Advanced Cervical Adenosquamous Carcinoma
Advanced Cervical Squamous Cell Carcinoma
Advanced Vaginal Adenocarcinoma
Advanced Vaginal Adenosquamous Carcinoma
Advanced Vaginal Squamous Cell Carcinoma
Stage IB2 Cervical Cancer AJCC v6 and v7
Stage II Cervical Cancer AJCC v7
Stage II Vaginal Cancer AJCC v6 and v7
Stage III Vaginal Cancer AJCC v6 and v7
Stage IIIB Cervical Cancer AJCC v6 and v7
Stage IVA Cervical Cancer AJCC v6 and v7
Stage IVA Vaginal Cancer AJCC v6 and v7
Interventions
PROCEDURE
RADIATION
DRUG
OTHER
1052
Participants
A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2015-11-27
Completion:
2020-09-07
Conditions
Prostate Cancer
Interventions
DRUG
154
Participants
A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2015-02-02
Completion:
2026-12-31
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
400
Participants
RegisterNET - A Registry for Neuroendocrine Tumors in the USA and Worldwide
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2015-02-28
Completion:
2018-03-31
Conditions
Neuroendocrine Tumor
Carcinoid
Neuroendocrine Carcinoma
Interventions
DEVICE
No Results Yet
400
Participants
Core Biopsies for Establishing a Breast Tumor Tissue Repository
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2013-11-14
Completion:
2026-11-14
Conditions
Breast Cancer
Interventions
OTHER
No Results Yet
50
Participants
TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2014-05-20
Completion:
2020-12-31
Conditions
Adult Glioblastoma
Endometrial Clear Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Ovarian Clear Cell Cystadenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian Mucinous Cystadenocarcinoma
Ovarian Serous Cystadenocarcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Malignant Uterine Corpus Neoplasm
Recurrent Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Solid Neoplasm
Stage IIIA Fallopian Tube Cancer AJCC v7
Stage IIIA Ovarian Cancer AJCC v6 and v7
Stage IIIA Primary Peritoneal Cancer AJCC v7
Stage IIIB Fallopian Tube Cancer AJCC v7
Stage IIIB Ovarian Cancer AJCC v6 and v7
Stage IIIB Primary Peritoneal Cancer AJCC v7
Stage IIIC Fallopian Tube Cancer AJCC v7
Stage IIIC Ovarian Cancer AJCC v6 and v7
Stage IIIC Primary Peritoneal Cancer AJCC v7
Stage IV Fallopian Tube Cancer AJCC v6 and v7
Stage IV Ovarian Cancer AJCC v6 and v7
Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
BIOLOGICAL
OTHER
DRUG
260
Participants
Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2014-04-11
Completion:
2019-04-04
Conditions
Borderline Ovarian Serous Tumor
Micropapillary Serous Carcinoma
Ovarian Serous Adenocarcinoma
Primary Peritoneal Serous Adenocarcinoma
Recurrent Ovarian Low Grade Serous Adenocarcinoma
Recurrent Primary Peritoneal Serous Adenocarcinoma
Interventions
DRUG
OTHER
529
Participants
Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2014-03-10
Completion:
2018-10-24
Conditions
Anemia
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
DRUG
OTHER
BIOLOGICAL
2981
Participants
Study of COPD Subgroups and Biomarkers
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2010-11-30
Completion:
2031-06-17
Conditions
COPD
Chronic Obstructive Pulmonary Disease
Chronic Bronchitis
Emphysema
No Results Yet
660
Participants
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2013-06-23
Completion:
2028-10-13
Conditions
Medulloblastoma
Interventions
RADIATION
DRUG
OTHER
No Results Yet
613
Participants
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2013-03-22
Completion:
2027-01-01
Conditions
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma
Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7
Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions
DRUG
PROCEDURE
BIOLOGICAL
RADIATION
OTHER
No Results Yet
50000
Participants
The MURDOCK Study Registry and Biorepository Horizon 1.5
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2009-02-28
Completion:
2026-12-31
Conditions
Chronic Disease
Healthy Volunteers
Interventions
GENETIC
No Results Yet
300
Participants
Lysosomal Acid Lipase (LAL) Deficiency Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2013-05-30
Completion:
2029-08-30
Conditions
Lysosomal Acid Lipase Deficiency
Cholesterol Ester Storage Disease
Wolman Disease
Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Acid Lipase Deficiency
LIPA Deficiency
LAL-Deficiency
No Results Yet
136
Participants
Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2013-01-14
Completion:
2027-03-01
Conditions
Hodgkin's Disease
Non-Hodgkin's Lymphoma
Lymphoproliferative Disease
Lymphoma
Interventions
BIOLOGICAL
No Results Yet
15000
Participants
Patient Retrospective Outcomes (PRO)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2012-04-03
Completion:
2030-12-31
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
162
Participants
Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2010-02-04
Completion:
2011-10-10
Conditions
Ovarian Cancer
Interventions
DRUG
50000
Participants
NARCOMS Registry: A Multiple Sclerosis Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
1996-01-31
Completion:
2050-12-31
Conditions
Multiple Sclerosis
No Results Yet
180
Participants
TMC125-TiDP35-C239 - Continued Access to Etravirine (ETR) in Treatment Experienced HIV-1 Infected Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2009-12-09
Completion:
2020-11-25
Conditions
HIV Infections
HIV-1
Interventions
DRUG
Showing 40 trials per page · Total 107726 trials