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Clinical Trials

Showing trials with last updates posted in 2025.

NCT00904241 | ACTIVE_NOT_RECRUITING
10000 Participants

Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2000-11-06
Completion: 2100-01-01
Conditions
Ganglioneuroblastoma Localized Resectable Neuroblastoma Localized Unresectable Neuroblastoma Regional Neuroblastoma Stage 4 Neuroblastoma Stage 4S Neuroblastoma
Interventions
OTHER
No Results Yet
NCT00600496 | ACTIVE_NOT_RECRUITING | PHASE1
140 Participants

A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2007-12-14
Completion: 2010-08-20
Conditions
Breast Cancer Breast Neoplasms Colon Cancer Colonic Cancer Colon Neoplasms Lung Cancer Melanoma Kidney Cancer
Interventions
DRUG
No Results Yet
NCT00463814 | ACTIVE_NOT_RECRUITING | PHASE1
58 Participants

AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2007-03-08
Completion: 2008-06-17
Conditions
Tumor Cancer
Interventions
DRUG
No Results Yet
NCT00310180 | ACTIVE_NOT_RECRUITING | PHASE3
10273 Participants

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2006-04-07
Completion: 2018-03-02
Conditions
Breast Adenocarcinoma Hormone Receptor Positive Stage IA Breast Cancer AJCC v7 Stage IB Breast Cancer AJCC v7 Stage IIA Breast Cancer AJCC v6 and v7 Stage IIB Breast Cancer AJCC v6 and v7 Stage IIIB Breast Cancer AJCC v7
Interventions
DRUG OTHER RADIATION
Results Available
NCT00304148 | ACTIVE_NOT_RECRUITING
5499 Participants

SDCC - Prospective Cohort Study of Chronic Renal Insufficiency

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2003-07-31
Completion: 2028-06-30
Conditions
Renal Insufficiency, Chronic
No Results Yet
NCT07227610 | NOT_YET_RECRUITING | PHASE2
54 Participants

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-31
Completion: 2029-01-31
Conditions
Brain Metastases Cancer (With CNS Involvement)
Interventions
RADIATION
No Results Yet
NCT07227597 | NOT_YET_RECRUITING | PHASE1/PHASE2
170 Participants

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-12
Completion: 2030-11-29
Conditions
Small Cell Lung Cancer Extensive Stage
Interventions
DRUG
No Results Yet
NCT07227584 | NOT_YET_RECRUITING | PHASE2
67 Participants

ALL Backbone in AYAs

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-04-30
Completion: 2030-07-31
Conditions
Acute Lymphoblastic Leukemia Philadelphia Chromosome-Negative Lymphoblastic Leukemia Acute Lymphoblastic Leukemia (ALL) Leukemia
Interventions
DRUG
No Results Yet
NCT07227571 | NOT_YET_RECRUITING | PHASE1
30 Participants

Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Osteosarcoma, FIERCe Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-05-01
Completion: 2044-01-31
Conditions
Advanced Osteosarcoma
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT07227545 | NOT_YET_RECRUITING | NA
18 Participants

High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2026-11-30
Conditions
Alcohol Use Disorder (AUD)
Interventions
DEVICE
No Results Yet
NCT07227532 | RECRUITING | NA
276 Participants

A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-21
Completion: 2030-12-31
Conditions
Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT07227493 | RECRUITING
45 Participants

Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-24
Completion: 2027-01-31
Conditions
Open Pilon Fractures
Interventions
DEVICE
No Results Yet
NCT07227480 | NOT_YET_RECRUITING | NA
40 Participants

Advancing Lung Cancer Screening One Text at a Time

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2026-07-31
Conditions
Lung Cancer Screening
Interventions
BEHAVIORAL
No Results Yet
NCT07227467 | RECRUITING
100 Participants

Prospective Assessments Following Immediate Lymphatic Reconstruction

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2030-12-31
Conditions
Lymphatic Reconstruction
Interventions
OTHER
No Results Yet
NCT07227454 | NOT_YET_RECRUITING | PHASE3
258 Participants

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-20
Completion: 2031-04-09
Conditions
Depressive Disorder, Major
Interventions
DRUG OTHER
No Results Yet
NCT07227441 | RECRUITING
200 Participants

Chronic Infections and Inflammation in ME/CFS: An Observational Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2030-09-30
Conditions
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
No Results Yet
NCT07227428 | NOT_YET_RECRUITING | PHASE4
206 Participants

Comparison of Glucocorticoid Tapering Schedules in Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2027-12-31
Conditions
Rheumatoid Arthritis (RA)
Interventions
DRUG
No Results Yet
NCT07227415 | NOT_YET_RECRUITING | PHASE1/PHASE2
224 Participants

A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-04
Completion: 2027-11-02
Conditions
Carcinoma, Renal Cell Advanced Renal Cell Carcinoma Renal Cancer Renal Neoplasm Clear Cell Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Clear-cell Metastatic Renal Cell Carcinoma Carcinoma, Renal Cell Metastasis Advanced or Metastatic Renal Cell Carcinoma Carcinoma, Renal Cell, Advanced Metastatic Renal Cell Cancer Metastatic Renal Cell Carcinoma ( mRCC) Metastatic/Advanced Renal Cell Carcinoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT07227402 | NOT_YET_RECRUITING | PHASE3
904 Participants

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-29
Completion: 2032-02-27
Conditions
Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07227389 | NOT_YET_RECRUITING
52 Participants

Timing of Opioid Administration and Postoperative Respiratory Depression.

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2028-12-01
Conditions
Opiod-Related Disorders Respiration Rate Detection Post-operative Respiratory Depression
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07227376 | RECRUITING
250 Participants

Data Collection Using Eko Digital Devices in a Clinical Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-14
Completion: 2026-04-01
Conditions
Lung Diseases
Interventions
DEVICE
No Results Yet
NCT07227363 | RECRUITING | NA
40 Participants

Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-01
Completion: 2025-12-31
Conditions
PCOS (Polycystic Ovary Syndrome)
Interventions
OTHER DIETARY_SUPPLEMENT
No Results Yet
NCT07227350 | NOT_YET_RECRUITING | PHASE2
180 Participants

L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2030-12-31
Conditions
Locally Advanced Basal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07227324 | RECRUITING
1000 Participants

Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-26
Completion: 2027-04-30
Conditions
Cannabis Use Cancer
No Results Yet
NCT07227311 | NOT_YET_RECRUITING | PHASE2
200 Participants

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-14
Completion: 2030-07-10
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT07227298 | NOT_YET_RECRUITING | PHASE1/PHASE2
162 Participants

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2029-03-08
Conditions
Advanced/Metastatic Non-Small Cell Lung Cancer Carcinoma, Non-Small Cell Lung Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT07227285 | NOT_YET_RECRUITING | PHASE1/PHASE2
16 Participants

Long-term Follow-up Study of Patients Who Received EG110A, a Non-replicative Herpes Simplex Virus 1-derived Gene Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-04-30
Completion: 2031-04-30
Conditions
Urinary Bladder, Overactive Spinal Cord Injury
Interventions
OTHER DRUG
No Results Yet
NCT07227272 | RECRUITING | NA
40 Participants

Early Childhood Dietary Assessment Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-15
Completion: 2026-04-30
Conditions
Dietary Assessment
Interventions
OTHER
No Results Yet
NCT07227259 | RECRUITING | NA
40 Participants

Health Properties of Pecan Nut Consumption

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-15
Completion: 2027-12-31
Conditions
Healthy Adults
Interventions
OTHER
No Results Yet
NCT07227246 | RECRUITING | PHASE3
350 Participants

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-06
Completion: 2029-01-31
Conditions
Intracerebral Hemorrhage
Interventions
BIOLOGICAL
No Results Yet
NCT07227233 | NOT_YET_RECRUITING | PHASE2
105 Participants

Artificial Intelligence and Machine Learning to Guide CDK4/6 Inhibitor Rechallenge in Breast Cancer.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-12-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT07227220 | COMPLETED | EARLY_PHASE1
15 Participants

Summer Youth Employment Programs for Health Promotion

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-31
Completion: 2025-07-07
Conditions
Obesity, Childhood Behavior, Health Healthy Lifestyle
Interventions
BEHAVIORAL
No Results Yet
NCT07227207 | NOT_YET_RECRUITING | PHASE1/PHASE2
72 Participants

A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2029-03-31
Conditions
Alpha-1 Antitrypsin Deficiency (AATD)
Interventions
DRUG
No Results Yet
NCT07227194 | COMPLETED
53065 Participants

Machine Learning Assessment of Next-Day Migraine Likelihood

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-07
Completion: 2025-08-01
Conditions
Migraine
No Results Yet
NCT07227181 | COMPLETED | NA
64 Participants

2025 Animal Assisted Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-23
Completion: 2025-08-13
Conditions
Anxiety Trauma Hospitalized Adult Patients Rehabilitation Physical Mobility Impairment Therapy Dog
Interventions
OTHER
No Results Yet
NCT07227168 | RECRUITING | PHASE1
200 Participants

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2027-12-31
Conditions
Head and Neck Squamous Cell Carcinoma HNSCC Non-Small Cell Lung Cancer NSCLC Esophageal Cancer Gastric Cancer Colorectal Cancer Pancreatic Ductal Adenocarcinoma (PDAC) Cervical Cancer Endometrial Cancer Urothelial Cancer
Interventions
DRUG
No Results Yet
NCT07227155 | NOT_YET_RECRUITING
375 Participants

The HOPE Biobank Resource

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-27
Completion: 2031-03-30
Conditions
Aplastic Anemias Hemoglobinopathies Bone Marrow Failure
No Results Yet
NCT07227142 | NOT_YET_RECRUITING | NA
100 Participants

IceBath: NOICE vs Nothing

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-02-01
Completion: 2027-01-31
Conditions
Pain
Interventions
BEHAVIORAL
No Results Yet
NCT07227129 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-12
No Results Yet
NCT07227116 | RECRUITING
280 Participants

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-01
Completion: 2026-04-30
Conditions
Complex Aneuploidy Chaotic Aneuploidy
No Results Yet
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